C4B63_46g91

leucyl-tRNA synthetase
Trypanosoma cruzi Dm28c 2018 OG6: OG6_101014 OG7: OG7_0005523 150 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 150 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_14g97 ⚠
isoleucyl-tRNA synthetase
— Both
C4B63_14g96 ⚠
isoleucil-tRNA synthetase
— Both
C4B63_79g37
methionyl-tRNA synthetase
— Both
C4B63_10g517 ⚠
tryptophanyl-tRNA synthetase
— OG6
C4B63_39g329
glycyl-tRNA synthetase
— Both
C4B63_82g71 ⚠
tryptophanyl-tRNA synthetase
— OG6
C4B63_425g4 ⚠
tyrosyl or methionyl-tRNA synthetase
— OG7
C4B63_76g56 ⚠
Aminoacyl tRNA synthase complex-interacting m
— OG7
C4B63_55g95 ⚠
tyrosyl or methionyl-tRNA synthetase
— OG7
C4B63_18g212
valyl-tRNA synthetase
— Both
C4B63_52g161 ⚠
tyrosyl-tRNA synthetase
— Both
C4B63_25g214 ⚠
conserved hypothetical protein
— OG7
C4B63_104g78 ⚠
calreticulin
— Both
C4B63_255g21 ⚠
calreticulin
— Both
C4B63_4g258
prolyl-tRNA synthetase
— Both
C4B63_30g247
glucosamine-fructose-6-phosphate aminotransfe
— Both
C4B63_114g25
conserved hypothetical protein
— Both
C4B63_34g120 ⚠
kinetoplast polyadenylation/uridylation facto
— Both
C4B63_109g39 ⚠
kinetoplast polyadenylation/uridylation facto
— Both
C4B63_76g41
Probable S-adenosyl-L-methionine-binding prot
— Both
C4B63_49g81 ⚠
translation initiation factor IF-2
— Both
C4B63_49g164 ⚠
alanyl-tRNA synthetase
— Both
C4B63_49g165 ⚠
alanyl-tRNA synthetase
— Both
C4B63_49g166 ⚠
alanyl-tRNA synthetase
— Both
C4B63_6g521 ⚠
DIS3-like exonuclease
— Both
C4B63_109g37 ⚠
Gar1/Naf1 RNA binding region containing prote
— Both
C4B63_34g118 ⚠
conserved hypothetical protein
— Both
C4B63_56g84 ⚠
conserved hypothetical protein
— Both
C4B63_56g85 ⚠
conserved hypothetical protein
— Both
C4B63_23g248 ⚠
inorganic pyrophosphatase
— Both
C4B63_70g77 ⚠
acidocalcisomal pyrophosphatase
— Both
C4B63_30g129 ⚠
rrp44p homologue
— OG7
C4B63_276g11 ⚠
DIS3-like exonuclease(fragment)
— OG7
C4B63_72g106 ⚠
DIS3-like exonuclease(fragment)
— OG7
C4B63_3g864 ⚠
Mucin-associated surface protein (MASP)
— OG7
C4B63_2g798 ⚠
Putative pentatricopeptide repeat-containing
— OG7
C4B63_28g212 ⚠
translation initiation factor IF-2
— OG7
C4B63_32g9 ⚠
translation initiation factor IF-2
— OG7
C4B63_49g80 ⚠
translation initiation factor IF-2
— OG7
C4B63_216g37 ⚠
translation initiation factor IF-2
— OG7
C4B63_28g210 ⚠
translation initiation factor IF-2
— OG7
C4B63_28g211 ⚠
translation initiation factor IF-2
— OG7
C4B63_1g121c ⚠
cytochrome b5-like protein
— OG7
C4B63_313g3 ⚠
dihydrouridine synthase (Dus)(fragment)
— OG7
C4B63_20g51 ⚠
tRNA-dihydrouridine synthase 4
— OG7
C4B63_336g10 ⚠
dihydrouridine synthase (Dus)
— OG7
C4B63_63g36 ⚠
prolyl endopeptidase
— OG7
C4B63_25g216 ⚠
conserved hypothetical protein
— OG7
C4B63_14g48 ⚠
rab-like GTPase activating protein
— OG7
C4B63_350g11 ⚠
dihydrouridine synthase (Dus)
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.