C4B63_28g212

translation initiation factor IF-2
Trypanosoma cruzi Dm28c 2018 OG6: OG6_147564 OG7: OG7_0005015 132 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 132 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_55g95 ⚠
tyrosyl or methionyl-tRNA synthetase
— OG7
C4B63_18g138 ⚠
UV excision repair RAD23-like protein
— OG7
C4B63_34g372 ⚠
cytochrome b-domain protein
— OG7
C4B63_3g864 ⚠
Mucin-associated surface protein (MASP)
— OG7
C4B63_49g165 ⚠
alanyl-tRNA synthetase
— OG7
C4B63_425g4 ⚠
tyrosyl or methionyl-tRNA synthetase
— OG7
C4B63_79g37 ⚠
methionyl-tRNA synthetase
— OG7
C4B63_56g84 ⚠
conserved hypothetical protein
— OG7
C4B63_84g58 ⚠
conserved hypothetical protein
— OG7
C4B63_149g26 ⚠
GDP-mannose pyrophosphorylase
— OG7
C4B63_339g3 ⚠
tRNA-dihydrouridine synthase 3
— OG7
C4B63_54g28 ⚠
conserved hypothetical protein
— OG7
C4B63_93g69 ⚠
tRNA (Uracil-5-)-methyltransferase
— OG7
C4B63_42g203 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_58g37 ⚠
conserved hypothetical protein
— OG7
C4B63_43g202 ⚠
hook complex protein, conserved
— OG7
C4B63_22g116 ⚠
Pre-mRNA-splicing factor 38
— OG7
C4B63_42g178 ⚠
histidyl-tRNA synthetase
— OG7
C4B63_4g140 ⚠
conserved hypothetical protein
— OG7
C4B63_2g382 ⚠
Proteinaceous RNase P 2
— OG7
C4B63_168g16 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_14g96 ⚠
isoleucil-tRNA synthetase
— OG7
C4B63_322g8 ⚠
dihydrouridine synthase (Dus)
— OG7
C4B63_355g19 ⚠
inositol-3-phosphate synthase(fragment)
— OG7
C4B63_19g179 ⚠
protein kinase
— OG7
C4B63_6g322 ⚠
conserved hypothetical protein
— OG7
C4B63_276g11 ⚠
DIS3-like exonuclease(fragment)
— OG7
C4B63_70g572c ⚠
cytochrome b5
— OG7
C4B63_42g180 ⚠
nitrate reductase
— OG7
C4B63_255g21 ⚠
calreticulin
— OG7
C4B63_7g79 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_22g292 ⚠
deoxyhypusine synthase
— OG7
C4B63_76g56 ⚠
Aminoacyl tRNA synthase complex-interacting m
— OG7
C4B63_4g375 ⚠
glucan 1,3-alpha-glucosidase
— OG7
C4B63_49g166 ⚠
alanyl-tRNA synthetase
— OG7
C4B63_30g247 ⚠
glucosamine-fructose-6-phosphate aminotransfe
— OG7
C4B63_58g38 ⚠
conserved hypothetical protein
— OG7
C4B63_4g502 ⚠
ABC transporter
— OG7
C4B63_7g306 ⚠
cleavage and polyadenylation specificity fact
— OG7
C4B63_7g358 ⚠
conserved hypothetical protein
— OG7
C4B63_244g4 ⚠
Nuclear migration protein nudC
— OG7
C4B63_25g1526c ⚠
Acyl-lipid (8-3)-desaturase
— OG7
C4B63_23g109 ⚠
UDP-glucose:glycoprotein glucosyltransferase
— OG7
C4B63_391g10 ⚠
conserved hypothetical protein
— OG7
C4B63_46g91 ⚠
leucyl-tRNA synthetase
— OG7
C4B63_348g23 ⚠
cytochrome b5
— OG7
C4B63_294g18 ⚠
dihydrouridine synthase (Dus)
— OG7
C4B63_42g172 ⚠
nuclear movement protein
— OG7
C4B63_10g403 ⚠
cytochrome b5
— OG7
C4B63_54g22 ⚠
conserved hypothetical protein
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.