C4B63_42g180

nitrate reductase
Trypanosoma cruzi Dm28c 2018 OG6: OG6_133565 OG7: OG7_0002230 149 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 149 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_4g245 ⚠
Multisite-specific tRNA:(cytosine-C(5))-methy
— OG7
C4B63_46g91 ⚠
leucyl-tRNA synthetase
— Both
C4B63_127g50 ⚠
Protein PPP4R3C
— Both
C4B63_142g3 ⚠
conserved hypothetical protein
— Both
C4B63_238g14 ⚠
conserved hypothetical protein
— Both
C4B63_114g43 ⚠
conserved hypothetical protein
— Both
C4B63_8g464 ⚠
protein kinase C substrate protein, heavy cha
— Both
C4B63_62g82 ⚠
thimet oligopeptidase
— Both
C4B63_37g366 ⚠
thimet oligopeptidase
— Both
C4B63_70g117 ⚠
Putative tRNA pseudouridine synthase Pus10
— Both
C4B63_104g78 ⚠
calreticulin
— Both
C4B63_255g21 ⚠
calreticulin
— Both
C4B63_51g192 ⚠
protein kinase A regulatory subunit
— Both
C4B63_30g247 ⚠
glucosamine-fructose-6-phosphate aminotransfe
— Both
C4B63_114g25 ⚠
conserved hypothetical protein
— Both
C4B63_34g120 ⚠
kinetoplast polyadenylation/uridylation facto
— Both
C4B63_109g39 ⚠
kinetoplast polyadenylation/uridylation facto
— Both
C4B63_30g290 ⚠
mercaptopyruvate sulfurtransferase
— Both
C4B63_49g81 ⚠
translation initiation factor IF-2
— Both
C4B63_9g293 ⚠
Mitochondrial-processing peptidase subunit al
— Both
C4B63_49g164 ⚠
alanyl-tRNA synthetase
— Both
C4B63_49g165 ⚠
alanyl-tRNA synthetase
— Both
C4B63_49g166 ⚠
alanyl-tRNA synthetase
— Both
C4B63_6g521 ⚠
DIS3-like exonuclease
— Both
C4B63_109g37 ⚠
Gar1/Naf1 RNA binding region containing prote
— Both
C4B63_34g118 ⚠
conserved hypothetical protein
— Both
C4B63_56g84 ⚠
conserved hypothetical protein
— Both
C4B63_56g85 ⚠
conserved hypothetical protein
— Both
C4B63_23g248 ⚠
inorganic pyrophosphatase
— Both
C4B63_70g77 ⚠
acidocalcisomal pyrophosphatase
— Both
C4B63_30g129 ⚠
rrp44p homologue
— OG7
C4B63_276g11 ⚠
DIS3-like exonuclease(fragment)
— OG7
C4B63_72g106 ⚠
DIS3-like exonuclease(fragment)
— OG7
C4B63_102g61 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_206g11 ⚠
ABC transporter
— OG7
C4B63_25g214 ⚠
conserved hypothetical protein
— OG7
C4B63_113g34 ⚠
ABC transporter
— OG7
C4B63_294g17 ⚠
dihydrouridine synthase (Dus)
— OG7
C4B63_133g172c ⚠
conserved hypothetical protein
— OG7
C4B63_58g38 ⚠
conserved hypothetical protein
— OG7
C4B63_7g306 ⚠
cleavage and polyadenylation specificity fact
— OG7
C4B63_42g172 ⚠
nuclear movement protein
— OG7
C4B63_294g18 ⚠
dihydrouridine synthase (Dus)
— OG7
C4B63_80g15 ⚠
cAMP response protein 1
— OG7
C4B63_7g236 ⚠
regulatory subunit of protein kinase a-like p
— OG7
C4B63_58g112 ⚠
mitochondrial processing peptidase alpha subu
— OG7
C4B63_95g34 ⚠
mitochondrial processing peptidase alpha subu
— OG7
C4B63_3g864 ⚠
Mucin-associated surface protein (MASP)
— OG7
C4B63_28g210 ⚠
translation initiation factor IF-2
— OG7
C4B63_49g80 ⚠
translation initiation factor IF-2
— OG7
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.