C4B63_322g8

dihydrouridine synthase (Dus)
Trypanosoma cruzi Dm28c 2018 OG6: OG6_101867 OG7: OG7_0002064 248 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 248 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_18g157 ⚠
DNA ligase I
— Both
C4B63_114g25 ⚠
conserved hypothetical protein
— OG7
C4B63_168g16 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_42g203 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_42g202 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_42g89 ⚠
importin alpha
— OG7
C4B63_114g43 ⚠
conserved hypothetical protein
— OG7
C4B63_238g14 ⚠
conserved hypothetical protein
— OG7
C4B63_109g39 ⚠
kinetoplast polyadenylation/uridylation facto
— OG7
C4B63_34g120 ⚠
kinetoplast polyadenylation/uridylation facto
— OG7
C4B63_142g3 ⚠
conserved hypothetical protein
— OG7
C4B63_2g798 ⚠
Putative pentatricopeptide repeat-containing
— OG7
C4B63_8g191 ⚠
JmjC domain-containing protein E
— OG7
C4B63_18g279 ⚠
C-1-tetrahydrofolate synthase, cytoplasmic
— OG7
C4B63_197g37 ⚠
JmjC domain-containing protein E
— OG7
C4B63_14g48 ⚠
rab-like GTPase activating protein
— OG7
C4B63_14g50 ⚠
disgorgin
— OG7
C4B63_42g216 ⚠
disgorgin
— OG7
C4B63_101g15 ⚠
serine peptidase, Clan SC, Family S9B
— OG7
C4B63_4g375 ⚠
glucan 1,3-alpha-glucosidase
— OG7
C4B63_127g50 ⚠
Protein PPP4R3C
— OG7
C4B63_40g73 ⚠
glycosyl hydrolase-like protein
— OG7
C4B63_3g864 ⚠
Mucin-associated surface protein (MASP)
— OG7
C4B63_227g2 ⚠
glucan 1,3-alpha-glucosidase
— OG7
C4B63_124g7 ⚠
Pre-mRNA-splicing factor 38
— OG7
C4B63_22g116 ⚠
Pre-mRNA-splicing factor 38
— OG7
C4B63_2g431 ⚠
GTPase protein
— OG7
C4B63_70g77 ⚠
acidocalcisomal pyrophosphatase
— OG7
C4B63_23g248 ⚠
inorganic pyrophosphatase
— OG7
C4B63_2g345 ⚠
GTP-binding protein
— OG7
C4B63_91g35 ⚠
GTPase
— OG7
C4B63_8g202 ⚠
GTP-binding protein
— OG7
C4B63_35g166 ⚠
XRN 5'-3' exonuclease N-terminus
— OG7
C4B63_57g113 ⚠
Flagellar Member 2
— OG7
C4B63_11g9 ⚠
eukaryotic translation initiation factor 3 su
— OG7
C4B63_2g823 ⚠
acyl-CoA dehydrogenase
— OG7
C4B63_21g280 ⚠
ribonuclease mar1
— OG7
C4B63_255g21 ⚠
calreticulin
— OG7
C4B63_104g78 ⚠
calreticulin
— OG7
C4B63_4g182 ⚠
Serine/threonine-protein phosphatase 4 regula
— OG7
C4B63_95g26 ⚠
conserved hypothetical protein
— OG7
C4B63_47g107 ⚠
ABC transporter
— OG7
C4B63_35g181 ⚠
SMP-30/Gluconolaconase/LRE-like region
— OG7
C4B63_70g117 ⚠
Putative tRNA pseudouridine synthase Pus10
— OG7
C4B63_206g11 ⚠
ABC transporter
— OG7
C4B63_113g34 ⚠
ABC transporter
— OG7
C4B63_60g137 ⚠
SMP-30/Gluconolaconase/LRE-like region
— OG7
C4B63_4g502 ⚠
ABC transporter
— OG7
C4B63_93g69 ⚠
tRNA (Uracil-5-)-methyltransferase
— OG7
C4B63_25g260 ⚠
TBC1 domain family member 5
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.