C4B63_8g191

JmjC domain-containing protein E
Trypanosoma cruzi Dm28c 2018 OG6: OG6_104630 OG7: OG7_0001931 83 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 83 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_22g77 ⚠
conserved hypothetical protein
— Both
C4B63_81g40 ⚠
ATP-dependent DEAD/H RNA helicase
— OG7
C4B63_58g54 ⚠
serine/threonine protein kinase
— OG7
C4B63_242g2 ⚠
protein kinase
— OG7
C4B63_294g17 ⚠
dihydrouridine synthase (Dus)
— OG7
C4B63_18g247 ⚠
GTPase activating protein of Rab-like GTPase(
— OG7
C4B63_63g81 ⚠
protein transport protein Sec23A
— OG7
C4B63_45g221 ⚠
ATP-dependent DEAD/H RNA helicase
— OG7
C4B63_207g22 ⚠
ATP-dependent RNA helicase HEL67
— OG7
C4B63_31g58 ⚠
ATP-dependent DEAD/H RNA helicase
— OG7
C4B63_4g90 ⚠
ATP-dependent RNA helicase HEL67
— OG7
C4B63_72g106 ⚠
DIS3-like exonuclease(fragment)
— OG7
C4B63_43g202 ⚠
hook complex protein, conserved
— OG7
C4B63_94g58 ⚠
ATP-dependent DEAD/H RNA helicase
— OG7
C4B63_2g782 ⚠
ATP-dependent RNA helicase
— OG7
C4B63_21g245 ⚠
ATP-dependent DEAD/H RNA helicase
— OG7
C4B63_271g10 ⚠
conserved hypothetical protein
— OG7
C4B63_93g64 ⚠
amidohydrolase
— Both
C4B63_93g65 ⚠
amidohydrolase
— Both
C4B63_122g20 ⚠
ribonucleoside-diphosphate reductase small ch
— Both
C4B63_27g3 ⚠
ribonucleoside-diphosphate reductase small ch
— Both
C4B63_49g166 ⚠
alanyl-tRNA synthetase
— Both
C4B63_336g10 ⚠
dihydrouridine synthase (Dus)
— OG7
C4B63_17g50 ⚠
Outer row dynein-assembly protein 7
— OG7
C4B63_40g163 ⚠
leucine-rich repeat protein (LRRP)
— OG7
C4B63_294g18 ⚠
dihydrouridine synthase (Dus)
— OG7
C4B63_13g41 ⚠
protein kinase
— OG7
C4B63_6g391 ⚠
protein kinase
— OG7
C4B63_54g35 ⚠
protein kinase
— OG7
C4B63_76g131 ⚠
protein kinase
— OG7
C4B63_13g118 ⚠
tRNA-dihydrouridine synthase 2
— OG7
C4B63_20g51 ⚠
tRNA-dihydrouridine synthase 4
— OG7
C4B63_49g164 ⚠
alanyl-tRNA synthetase
— Both
C4B63_313g3 ⚠
dihydrouridine synthase (Dus)(fragment)
— OG7
C4B63_350g11 ⚠
dihydrouridine synthase (Dus)
— OG7
C4B63_13g231 ⚠
serine/threonine protein kinase
— OG7
C4B63_276g11 ⚠
DIS3-like exonuclease(fragment)
— OG7
C4B63_322g8 ⚠
dihydrouridine synthase (Dus)
— OG7
C4B63_45g139 ⚠
serine/threonine protein kinase
— OG7
C4B63_4g180 ⚠
serine/threonine protein kinase
— OG7
C4B63_18g248 ⚠
GTPase activating protein of Rab-like GTPase
— OG7
C4B63_30g129 ⚠
rrp44p homologue
— OG7
C4B63_75g57 ⚠
U3 small nucleolar RNA-associated protein 6
— Both
C4B63_95g26 ⚠
conserved hypothetical protein
— Both
C4B63_23g122 ⚠
serine/threonine protein kinase
— Both
C4B63_339g3 ⚠
tRNA-dihydrouridine synthase 3
— Both
C4B63_4g182 ⚠
Serine/threonine-protein phosphatase 4 regula
— Both
C4B63_25g260 ⚠
TBC1 domain family member 5
— Both
C4B63_12g208 ⚠
leucine-rich repeat protein (LRRP)
— Both
C4B63_30g247 ⚠
glucosamine-fructose-6-phosphate aminotransfe
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.