C4B63_45g139

serine/threonine protein kinase
Trypanosoma cruzi Dm28c 2018 OG6: OG6_105113 OG7: OG7_0000009 219 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 219 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_2g333 ⚠
conserved hypothetical protein
— OG7
C4B63_25g235 ⚠
Protein OSCP1
— OG7
C4B63_49g165 ⚠
alanyl-tRNA synthetase
— OG7
C4B63_12g208 ⚠
leucine-rich repeat protein (LRRP)
— OG7
C4B63_6g521 ⚠
DIS3-like exonuclease
— OG7
C4B63_72g106 ⚠
DIS3-like exonuclease(fragment)
— OG7
C4B63_46g15 ⚠
Kinesin-13 5
— OG7
C4B63_325g1 ⚠
Kinesin-13 1
— OG7
C4B63_69g61 ⚠
Kinesin-13 1
— OG7
C4B63_276g11 ⚠
DIS3-like exonuclease(fragment)
— OG7
C4B63_17g127 ⚠
Desumoylating isopeptidase 1
— OG7
C4B63_1g43 ⚠
DeSI-like protein At4g17486
— OG7
C4B63_1g48 ⚠
Deubiquitinase DESI2
— OG7
C4B63_235g21 ⚠
DeSI-like protein At4g17486
— OG7
C4B63_186g6 ⚠
Desumoylating isopeptidase 1
— OG7
C4B63_28g93 ⚠
DeSI-like protein At4g17486
— OG7
C4B63_44g235 ⚠
Kinesin-13 4
— OG7
C4B63_144g30 ⚠
Kinesin-13 1
— OG7
C4B63_30g129 ⚠
rrp44p homologue
— OG7
C4B63_294g18 ⚠
dihydrouridine synthase (Dus)
— OG7
C4B63_13g118 ⚠
tRNA-dihydrouridine synthase 2
— OG7
C4B63_20g51 ⚠
tRNA-dihydrouridine synthase 4
— OG7
C4B63_336g10 ⚠
dihydrouridine synthase (Dus)
— OG7
C4B63_26g265 ⚠
DNA repair protein Rad9
— OG7
C4B63_313g3 ⚠
dihydrouridine synthase (Dus)(fragment)
— OG7
C4B63_350g11 ⚠
dihydrouridine synthase (Dus)
— OG7
C4B63_22g292 ⚠
deoxyhypusine synthase
— OG7
C4B63_322g8 ⚠
dihydrouridine synthase (Dus)
— OG7
C4B63_26g317 ⚠
Alanyl-tRNA editing protein Aarsd1-B
— OG7
C4B63_35g129 ⚠
dihydroorotase
— Both
C4B63_31g228 ⚠
dihydroorotase
— Both
C4B63_279g8 ⚠
ubiquitin carboxyl-terminal hydrolase
— Both
C4B63_19g259 ⚠
conserved hypothetical protein
— Both
C4B63_48g23 ⚠
nicotinate phosphoribosyltransferase
— Both
C4B63_9g331 ⚠
transcription elongation factor s-II
— Both
C4B63_23g248 ⚠
inorganic pyrophosphatase
— Both
C4B63_70g77 ⚠
acidocalcisomal pyrophosphatase
— Both
C4B63_4g226 ⚠
UTP-glucose-1-phosphate uridylyltransferase 2
— Both
C4B63_89g43 ⚠
PITH domain-containing protein
— Both
C4B63_232g3 ⚠
TBC1 domain family member 5
— OG7
C4B63_18g247 ⚠
GTPase activating protein of Rab-like GTPase(
— OG7
C4B63_21g251 ⚠
conserved hypothetical protein
— OG7
C4B63_61g23 ⚠
tRNA-dihydrouridine synthase 3
— OG7
C4B63_339g3 ⚠
tRNA-dihydrouridine synthase 3
— OG7
C4B63_4g182 ⚠
Serine/threonine-protein phosphatase 4 regula
— OG7
C4B63_22g77 ⚠
conserved hypothetical protein
— OG7
C4B63_25g260 ⚠
TBC1 domain family member 5
— OG7
C4B63_18g248 ⚠
GTPase activating protein of Rab-like GTPase
— OG7
C4B63_136g37 ⚠
tRNA synthetases class II (A)/Threonyl and Al
— OG7
C4B63_57g113 ⚠
Flagellar Member 2
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.