C4B63_19g259

conserved hypothetical protein
Trypanosoma cruzi Dm28c 2018 OG6: OG6_129093 OG7: OG7_0004831 191 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 191 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_42g242 ⚠
2-hydroxy-3-oxopropionate reductase
— Both
C4B63_12g21 ⚠
Uncharacterized oxidoreductase YkwC
— OG7
C4B63_12g221 ⚠
pyruvate phosphate dikinase
— OG7
C4B63_17g249 ⚠
protein phosphatase 2C
— OG6
C4B63_10g437 ⚠
U-box domain protein
— Both
C4B63_22g64 ⚠
Poly(A) RNA polymerase GLD2-A
— Both
C4B63_12g300 ⚠
TAP42-like family
— Both
C4B63_4g137 ⚠
N-myristoyl transferase
— Both
C4B63_13g192 ⚠
Elongation factor G1, mitochondrial
— Both
C4B63_60g80 ⚠
dihydroorotase
— Both
C4B63_4g146 ⚠
pyruvate kinase 2
— Both
C4B63_227g20 ⚠
pyruvate kinase 2
— Both
C4B63_93g62 ⚠
Pentatricopeptide repeat-containing protein
— Both
C4B63_47g40 ⚠
CS domain containing protein
— Both
C4B63_4g226 ⚠
UTP-glucose-1-phosphate uridylyltransferase 2
— Both
C4B63_89g43 ⚠
PITH domain-containing protein
— Both
C4B63_79g87 ⚠
phosphoglucomutase
— Both
C4B63_2g235 ⚠
Co-chaperone protein P23
— Both
C4B63_13g230 ⚠
Eukaryotic translation initiation factor 6
— Both
C4B63_7g133 ⚠
pyroglutamyl-peptidase I
— Both
C4B63_10g488 ⚠
UBX domain-containing protein
— Both
C4B63_90g47 ⚠
UPF0652 protein
— Both
C4B63_2g177 ⚠
UPF0652 protein
— Both
C4B63_227g9 ⚠
mevalonate-diphosphate decarboxylase
— Both
C4B63_31g106 ⚠
conserved hypothetical protein
— Both
C4B63_132g69 ⚠
conserved hypothetical protein
— Both
C4B63_31g228 ⚠
dihydroorotase
— Both
C4B63_58g38 ⚠
conserved hypothetical protein
— Both
C4B63_4g383 ⚠
mevalonate-diphosphate decarboxylase
— Both
C4B63_175g8 ⚠
TPR-repeat protein
— OG6
C4B63_184g9 ⚠
protein phosphatase 2C
— OG6
C4B63_188g43 ⚠
conserved hypothetical protein
— Both
C4B63_11g25 ⚠
conserved hypothetical protein
— Both
C4B63_4g357 ⚠
Activator of 90 kDa heat shock protein ATPase
— Both
C4B63_35g191 ⚠
6-phosphogluconolactonase
— Both
C4B63_4g136 ⚠
N-myristoyl transferase
— Both
C4B63_48g23 ⚠
nicotinate phosphoribosyltransferase
— Both
C4B63_9g331 ⚠
transcription elongation factor s-II
— Both
C4B63_23g248 ⚠
inorganic pyrophosphatase
— Both
C4B63_70g77 ⚠
acidocalcisomal pyrophosphatase
— Both
C4B63_144g30 ⚠
Kinesin-13 1
— OG7
C4B63_44g235 ⚠
Kinesin-13 4
— OG7
C4B63_69g61 ⚠
Kinesin-13 1
— OG7
C4B63_325g1 ⚠
Kinesin-13 1
— OG7
C4B63_46g15 ⚠
Kinesin-13 5
— OG7
C4B63_2g432 ⚠
2-(3-amino-3-carboxypropyl)histidine synthase
— OG7
C4B63_4g348 ⚠
Bifunctional coenzyme A synthase
— OG7
C4B63_175g10 ⚠
aldo/keto reductase
— OG7
C4B63_87g11 ⚠
epsilon-adaptin(fragment)
— OG7
C4B63_23g122 ⚠
serine/threonine protein kinase
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.