C4B63_42g242

2-hydroxy-3-oxopropionate reductase
Trypanosoma cruzi Dm28c 2018 OG6: OG6_101839 OG7: OG7_0002731 260 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 260 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_13g189 ⚠
ubiquitin-like protein
— OG7
C4B63_19g259 ⚠
conserved hypothetical protein
— Both
C4B63_44g252 ⚠
ubiquitin carboxyl-terminal hydrolase
— Both
C4B63_171g22 ⚠
eukaryotic translation initiation factor 4E (
— OG7
C4B63_157g19 ⚠
eukaryotic translation initiation factor 4E (
— OG7
C4B63_40g36 ⚠
Enoyl-CoA hydratase/isomerase family
— OG7
C4B63_43g147 ⚠
mitochondrial RNA binding complex 1 subunit
— OG7
C4B63_13g154 ⚠
elongation factor 2
— OG7
C4B63_13g155 ⚠
elongation factor 2
— OG7
C4B63_9g523 ⚠
U5 small nuclear ribonucleoprotein component
— OG7
C4B63_13g156 ⚠
elongation factor 2
— OG7
C4B63_13g153 ⚠
elongation factor 2
— OG7
C4B63_13g157 ⚠
elongation factor 2
— OG7
C4B63_13g152 ⚠
elongation factor 2
— OG7
C4B63_175g10 ⚠
aldo/keto reductase
— OG7
C4B63_9g259 ⚠
conserved hypothetical protein
— OG7
C4B63_206g20 ⚠
conserved hypothetical protein
— OG7
C4B63_47g114 ⚠
conserved hypothetical protein
— OG7
C4B63_72g81 ⚠
conserved hypothetical protein
— OG7
C4B63_83g74 ⚠
conserved hypothetical protein
— OG7
C4B63_18g273 ⚠
conserved hypothetical protein
— OG7
C4B63_2g732 ⚠
conserved hypothetical protein
— OG7
C4B63_59g114 ⚠
conserved hypothetical protein
— OG7
C4B63_35g186 ⚠
50S ribosomal protein L17
— OG7
C4B63_51g197 ⚠
conserved hypothetical protein
— OG7
C4B63_51g196 ⚠
conserved hypothetical protein
— OG7
C4B63_46g15 ⚠
Kinesin-13 5
— OG7
C4B63_325g1 ⚠
Kinesin-13 1
— OG7
C4B63_69g61 ⚠
Kinesin-13 1
— OG7
C4B63_40g27 ⚠
conserved hypothetical protein
— OG7
C4B63_44g235 ⚠
Kinesin-13 4
— OG7
C4B63_144g30 ⚠
Kinesin-13 1
— OG7
C4B63_9g331 ⚠
transcription elongation factor s-II
— Both
C4B63_279g8 ⚠
ubiquitin carboxyl-terminal hydrolase
— Both
C4B63_113g52 ⚠
conserved hypothetical protein
— Both
C4B63_11g18 ⚠
translation elongation factor EF-2
— Both
C4B63_52g42 ⚠
glutathione synthetase
— Both
C4B63_160g33 ⚠
ubiquitin-activating enzyme E1
— Both
C4B63_2g786 ⚠
ubiquitin-activating enzyme E1
— Both
C4B63_16g331 ⚠
ubiquitin-activating enzyme E1
— Both
C4B63_54g62 ⚠
proteasome activator protein pa26
— Both
C4B63_2g70 ⚠
conserved hypothetical protein
— Both
C4B63_101g21 ⚠
conserved hypothetical protein
— Both
C4B63_17g179 ⚠
Importin subunit beta-3
— Both
C4B63_40g50 ⚠
metallo-peptidase, Clan MC, Family M14
— Both
C4B63_57g94 ⚠
ATP-dependent RNA helicase
— Both
C4B63_14g68 ⚠
paraflagellar rod component
— Both
C4B63_113g34 ⚠
ABC transporter
— Both
C4B63_11g17 ⚠
translation elongation factor EF-2
— Both
C4B63_2g823 ⚠
acyl-CoA dehydrogenase
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.