C4B63_6g391

protein kinase
Trypanosoma cruzi Dm28c 2018 OG6: OG6_146487 OG7: OG7_0000009 201 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 201 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_2g333 ⚠
conserved hypothetical protein
— OG7
C4B63_227g20 ⚠
pyruvate kinase 2
— OG7
C4B63_230g26 ⚠
tRNA threonylcarbamoyl adenosine modification
— OG7
C4B63_56g64 ⚠
Present in the outer mitochondrial membrane p
— OG7
C4B63_13g189 ⚠
ubiquitin-like protein
— OG7
C4B63_19g259 ⚠
conserved hypothetical protein
— OG7
C4B63_6g385 ⚠
tRNA threonylcarbamoyl adenosine modification
— OG7
C4B63_4g357 ⚠
Activator of 90 kDa heat shock protein ATPase
— OG7
C4B63_79g87 ⚠
phosphoglucomutase
— OG7
C4B63_142g6 ⚠
GMP synthase
— OG7
C4B63_238g18 ⚠
GMP synthase(fragment)
— OG7
C4B63_55g26 ⚠
conserved hypothetical protein
— OG7
C4B63_14g188 ⚠
UPF0769 protein C21orf59 homolog B
— OG7
C4B63_42g174 ⚠
conserved hypothetical protein
— OG7
C4B63_6g572 ⚠
5'-3' exoribonuclease A
— OG7
C4B63_25g220 ⚠
5'-3' exoribonuclease B
— OG7
C4B63_48g116 ⚠
5'-3' exoribonuclease D
— OG7
C4B63_2g177 ⚠
UPF0652 protein
— OG7
C4B63_90g47 ⚠
UPF0652 protein
— OG7
C4B63_6g148 ⚠
haloacid dehalogenase-like hydrolase
— OG7
C4B63_30g112 ⚠
haloacid dehalogenase hydrolase
— OG7
C4B63_6g146 ⚠
haloacid dehalogenase-like hydrolase
— OG7
C4B63_253g15 ⚠
haloacid dehalogenase-like hydrolase
— OG7
C4B63_112g33 ⚠
haloacid dehalogenase hydrolase
— OG7
C4B63_89g43 ⚠
PITH domain-containing protein
— OG7
C4B63_48g23 ⚠
nicotinate phosphoribosyltransferase
— OG7
C4B63_54g35 ⚠
protein kinase
— OG7
C4B63_23g248 ⚠
inorganic pyrophosphatase
— OG7
C4B63_70g77 ⚠
acidocalcisomal pyrophosphatase
— OG7
C4B63_35g191 ⚠
6-phosphogluconolactonase
— OG7
C4B63_17g263 ⚠
phosphomannose isomerase
— OG7
C4B63_17g264 ⚠
phosphomannose isomerase
— OG7
C4B63_4g180 ⚠
serine/threonine protein kinase
— OG7
C4B63_45g139 ⚠
serine/threonine protein kinase
— OG7
C4B63_23g122 ⚠
serine/threonine protein kinase
— OG7
C4B63_13g231 ⚠
serine/threonine protein kinase
— OG7
C4B63_242g2 ⚠
protein kinase
— OG7
C4B63_58g54 ⚠
serine/threonine protein kinase
— OG7
C4B63_76g131 ⚠
protein kinase
— OG7
C4B63_197g37 ⚠
JmjC domain-containing protein E
— OG7
C4B63_4g146 ⚠
pyruvate kinase 2
— OG7
C4B63_35g125 ⚠
transaldolase
— OG7
C4B63_7g361 ⚠
phosphomannomutase-like protein
— OG7
C4B63_9g488 ⚠
conserved hypothetical protein
— OG7
C4B63_8g191 ⚠
JmjC domain-containing protein E
— OG7
C4B63_13g41 ⚠
protein kinase
— OG7
C4B63_314g10 ⚠
5'-AMP-activated protein kinase subunit beta
— OG7
C4B63_16g11 ⚠
5'-AMP-activated protein kinase subunit beta
— OG7
C4B63_243g4 ⚠
Present in the outer mitochondrial membrane p
— OG7
C4B63_23g200 ⚠
Flagellum attachment zone protein 19
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.