C4B63_16g11

5'-AMP-activated protein kinase subunit beta
Trypanosoma cruzi Dm28c 2018 OG6: OG6_101253 OG7: OG7_0004018 120 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 120 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_42g203 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_23g240 ⚠
Eukaryotic translation initiation factor 2 su
— Both
C4B63_4g235 ⚠
5-oxoprolinase
— Both
C4B63_4g234 ⚠
5-oxoprolinase
— Both
C4B63_2g450 ⚠
metallo-peptidase, Clan MF, Family M17
— OG7
C4B63_413g14 ⚠
pumilio/PUF RNA binding protein 4
— OG7
C4B63_22g175 ⚠
pumilio/PUF RNA binding protein 9
— OG7
C4B63_6g592 ⚠
pumilio/PUF RNA binding protein 5
— OG7
C4B63_41g148 ⚠
pumilio/PUF RNA binding protein 4
— OG7
C4B63_439g12 ⚠
pumilio/PUF RNA binding protein 4
— OG7
C4B63_13g170 ⚠
pumilio/PUF RNA binding protein 1
— OG7
C4B63_43g137 ⚠
pumilio/PUF RNA binding protein 3
— OG7
C4B63_359g9 ⚠
conserved hypothetical protein
— OG7
C4B63_325g1 ⚠
Kinesin-13 1
— OG7
C4B63_271g10 ⚠
conserved hypothetical protein
— OG7
C4B63_102g61 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_14g171 ⚠
ubiquitin-protein ligase
— OG7
C4B63_9g489 ⚠
conserved hypothetical protein
— OG7
C4B63_8g527 ⚠
pseudouridylate synthase I
— OG7
C4B63_2g815 ⚠
conserved hypothetical protein
— OG7
C4B63_488g7 ⚠
conserved hypothetical protein
— OG7
C4B63_75g61 ⚠
calmodulin
— OG7
C4B63_92g124 ⚠
conserved hypothetical protein
— OG7
C4B63_46g15 ⚠
Kinesin-13 5
— OG7
C4B63_92g114 ⚠
conserved hypothetical protein
— OG7
C4B63_42g202 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_2g817 ⚠
conserved hypothetical protein
— OG7
C4B63_7g388 ⚠
geranylgeranyl transferase type II beta subun
— OG7
C4B63_144g30 ⚠
Kinesin-13 1
— OG7
C4B63_43g202 ⚠
hook complex protein, conserved
— OG7
C4B63_359g23 ⚠
CRAL/TRIO domain containing protein
— OG7
C4B63_10g524 ⚠
nuclear transcription factor
— OG7
C4B63_57g94 ⚠
ATP-dependent RNA helicase
— OG7
C4B63_13g41 ⚠
protein kinase
— OG7
C4B63_6g391 ⚠
protein kinase
— OG7
C4B63_54g35 ⚠
protein kinase
— OG7
C4B63_76g131 ⚠
protein kinase
— OG7
C4B63_58g54 ⚠
serine/threonine protein kinase
— OG7
C4B63_242g2 ⚠
protein kinase
— OG7
C4B63_45g139 ⚠
serine/threonine protein kinase
— OG7
C4B63_4g180 ⚠
serine/threonine protein kinase
— OG7
C4B63_56g51 ⚠
RNA-binding protein
— OG7
C4B63_56g50 ⚠
Surp module,
— OG7
C4B63_44g232 ⚠
CRAL/TRIO domain containing protein
— OG7
C4B63_6g517 ⚠
geranylgeranyl transferase type II beta subun
— OG7
C4B63_4g514 ⚠
tRNA pseudouridine synthase A-like protein
— OG7
C4B63_7g382 ⚠
ubiquitin-protein ligase
— OG7
C4B63_69g61 ⚠
Kinesin-13 1
— OG7
C4B63_249g12 ⚠
conserved hypothetical protein
— OG7
C4B63_44g235 ⚠
Kinesin-13 4
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.