C4B63_41g148

pumilio/PUF RNA binding protein 4
Trypanosoma cruzi Dm28c 2018 OG6: OG6_223533 OG7: OG7_0001979 52 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 52 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_56g50 ⚠
Surp module,
— OG7
C4B63_2g88 ⚠
ubiquitin-protein ligase
— OG7
C4B63_16g11 ⚠
5'-AMP-activated protein kinase subunit beta
— OG7
C4B63_8g190 ⚠
conserved hypothetical protein
— OG7
C4B63_197g36 ⚠
conserved hypothetical protein
— OG7
C4B63_47g49 ⚠
tRNA pseudouridine synthase 1
— OG7
C4B63_79g39 ⚠
conserved hypothetical protein
— OG7
C4B63_18g156 ⚠
protein mkt1
— OG7
C4B63_40g155 ⚠
conserved hypothetical protein
— OG7
C4B63_14g167 ⚠
conserved hypothetical protein,predicted C2 d
— OG7
C4B63_14g166 ⚠
conserved hypothetical protein
— OG7
C4B63_27g222 ⚠
leucine-rich repeat protein(fragment)
— OG7
C4B63_27g221 ⚠
leucine-rich repeat protein
— OG7
C4B63_7g382 ⚠
ubiquitin-protein ligase
— OG7
C4B63_56g51 ⚠
RNA-binding protein
— OG7
C4B63_20g161 ⚠
Intraflagellar transport protein 22
— OG7
C4B63_21g285 ⚠
conserved hypothetical protein
— OG7
C4B63_199g2 ⚠
conserved hypothetical protein
— OG7
C4B63_199g1 ⚠
conserved hypothetical protein
— OG7
C4B63_21g284 ⚠
conserved hypothetical protein
— OG7
C4B63_69g156 ⚠
conserved hypothetical protein
— OG7
C4B63_18g184 ⚠
ribosomal P protein AGP2beta-1
— OG7
C4B63_354g9 ⚠
ribosomal P protein AGP2beta-1
— OG7
C4B63_13g194 ⚠
Eukaryotic translation initiation factor 4E t
— OG7
C4B63_4g181 ⚠
Sestrin-3
— OG7
C4B63_4g349 ⚠
conserved hypothetical protein
— OG7
C4B63_28g91 ⚠
Kinesin-13 3
— OG7
C4B63_325g1 ⚠
Kinesin-13 1
— OG7
C4B63_16g140 ⚠
Paladin
— OG7
C4B63_2g376 ⚠
ribosome assembly protein RRB1
— OG7
C4B63_271g10 ⚠
conserved hypothetical protein
— OG7
C4B63_14g171 ⚠
ubiquitin-protein ligase
— OG7
C4B63_18g1175c ⚠
conserved hypothetical protein
— OG7
C4B63_9g489 ⚠
conserved hypothetical protein
— OG7
C4B63_8g527 ⚠
pseudouridylate synthase I
— OG7
C4B63_75g61 ⚠
calmodulin
— OG7
C4B63_46g15 ⚠
Kinesin-13 5
— OG7
C4B63_17g98 ⚠
E3 ubiquitin-protein ligase UPL3
— OG7
C4B63_18g147 ⚠
calmodulin
— OG7
C4B63_11g52 ⚠
conserved hypothetical protein
— OG7
C4B63_259g15 ⚠
Paladin
— OG7
C4B63_314g10 ⚠
5'-AMP-activated protein kinase subunit beta
— OG7
C4B63_144g30 ⚠
Kinesin-13 1
— OG7
C4B63_18g50 ⚠
microtubule associated protein xmap215
— OG7
C4B63_4g246 ⚠
AN1-type zinc finger protein 2B
— OG7
C4B63_43g202 ⚠
hook complex protein, conserved
— OG7
C4B63_22g94 ⚠
cyclophilin 15
— OG7
C4B63_44g235 ⚠
Kinesin-13 4
— OG7
C4B63_18g1166c ⚠
conserved hypothetical protein
— OG7
C4B63_4g514 ⚠
tRNA pseudouridine synthase A-like protein
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.