C4B63_48g116

5'-3' exoribonuclease D
Trypanosoma cruzi Dm28c 2018 OG6: OG6_100417 OG7: OG7_0003221 255 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 255 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_10g147 ⚠
carnitine O-acetyltransferase(fragment)
— OG6
C4B63_17g277 ⚠
phosphatidylinositol 3-related kinase
— OG7
C4B63_17g278 ⚠
phosphatidylinositol 3-related kinase
— OG7
C4B63_7g380 ⚠
phosphatidylinositol 3-kinase(fragment)
— OG7
C4B63_124g3 ⚠
phosphatidylinositol 3-kinase
— OG7
C4B63_124g2 ⚠
phosphatidylinositol 3-kinase
— OG7
C4B63_22g113 ⚠
phosphatidylinositol 3-kinase
— OG7
C4B63_175g10 ⚠
aldo/keto reductase
— OG7
C4B63_46g15 ⚠
Kinesin-13 5
— OG7
C4B63_325g1 ⚠
Kinesin-13 1
— OG7
C4B63_69g61 ⚠
Kinesin-13 1
— OG7
C4B63_44g235 ⚠
Kinesin-13 4
— OG7
C4B63_144g30 ⚠
Kinesin-13 1
— OG7
C4B63_9g331 ⚠
transcription elongation factor s-II
— Both
C4B63_114g23 ⚠
UBX domain-containing protein 3
— Both
C4B63_30g145 ⚠
electron-transfer-flavoprotein, alpha polypep
— Both
C4B63_16g163 ⚠
Pyridoxal phosphate homeostasis protein
— Both
C4B63_30g144 ⚠
Cilia- and flagella-associated protein 52
— Both
C4B63_28g64 ⚠
aspartate aminotransferase
— Both
C4B63_54g69 ⚠
aspartate aminotransferase
— Both
C4B63_34g361 ⚠
phosphatidylinositol kinase related protein
— Both
C4B63_279g8 ⚠
ubiquitin carboxyl-terminal hydrolase
— Both
C4B63_42g174 ⚠
conserved hypothetical protein
— Both
C4B63_243g4 ⚠
Present in the outer mitochondrial membrane p
— Both
C4B63_17g188 ⚠
Phosphopantetheine adenylyltransferase
— Both
C4B63_4g136 ⚠
N-myristoyl transferase
— Both
C4B63_35g191 ⚠
6-phosphogluconolactonase
— Both
C4B63_4g357 ⚠
Activator of 90 kDa heat shock protein ATPase
— Both
C4B63_6g148 ⚠
haloacid dehalogenase-like hydrolase
— Both
C4B63_69g27 ⚠
35 kDa cyclophilin
— OG6
C4B63_92g63 ⚠
KH domain/Domain of unknown function (DUF1771
— Both
C4B63_14g17 ⚠
small G-protein
— OG6
C4B63_31g106 ⚠
conserved hypothetical protein
— Both
C4B63_79g87 ⚠
phosphoglucomutase
— Both
C4B63_89g43 ⚠
PITH domain-containing protein
— Both
C4B63_2g235 ⚠
Co-chaperone protein P23
— Both
C4B63_253g15 ⚠
haloacid dehalogenase-like hydrolase
— Both
C4B63_13g230 ⚠
Eukaryotic translation initiation factor 6
— Both
C4B63_7g133 ⚠
pyroglutamyl-peptidase I
— Both
C4B63_70g77 ⚠
acidocalcisomal pyrophosphatase
— Both
C4B63_10g488 ⚠
UBX domain-containing protein
— Both
C4B63_48g23 ⚠
nicotinate phosphoribosyltransferase
— Both
C4B63_227g9 ⚠
mevalonate-diphosphate decarboxylase
— Both
C4B63_90g47 ⚠
UPF0652 protein
— Both
C4B63_2g177 ⚠
UPF0652 protein
— Both
C4B63_23g269 ⚠
conserved hypothetical protein
— Both
C4B63_17g264 ⚠
phosphomannose isomerase
— Both
C4B63_44g252 ⚠
ubiquitin carboxyl-terminal hydrolase
— Both
C4B63_175g8 ⚠
TPR-repeat protein
— OG6
C4B63_184g9 ⚠
protein phosphatase 2C
— OG6
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.