C4B63_17g188

Phosphopantetheine adenylyltransferase
Trypanosoma cruzi Dm28c 2018 OG6: OG6_101466 OG7: OG7_0003431 205 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 205 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_325g1 ⚠
Kinesin-13 1
— OG7
C4B63_3g1086 ⚠
monothiol glutaredoxin
— OG7
C4B63_42g205 ⚠
Eukaryotic translation initiation factor 4E-4
— OG7
C4B63_110g27 ⚠
Leucine-rich repeat-containing protein 34
— OG7
C4B63_225g44 ⚠
conserved hypothetical protein
— OG7
C4B63_4g577 ⚠
eukaryotic translation initiation factor 4E (
— OG7
C4B63_69g55 ⚠
monothiol glutaredoxin
— OG7
C4B63_43g124 ⚠
RNA polymerase II
— OG7
C4B63_282g13 ⚠
Elongation factor G 2, mitochondrial
— OG7
C4B63_9g448 ⚠
superoxide dismutase
— OG7
C4B63_6g234 ⚠
Elongation factor G 2, mitochondrial
— OG7
C4B63_219g40 ⚠
Leucine-rich repeat-containing protein
— OG7
C4B63_219g55 ⚠
Leucine-rich repeat-containing protein 34
— OG7
C4B63_236g16 ⚠
Leucine-rich repeat-containing protein 34
— OG7
C4B63_58g54 ⚠
serine/threonine protein kinase
— OG7
C4B63_6g395 ⚠
Elongation factor G 2, mitochondrial
— OG7
C4B63_242g2 ⚠
protein kinase
— OG7
C4B63_144g24 ⚠
monothiol glutaredoxin
— OG7
C4B63_392g17 ⚠
iron superoxide dismutase
— OG7
C4B63_80g53 ⚠
iron superoxide dismutase
— OG7
C4B63_171g22 ⚠
eukaryotic translation initiation factor 4E (
— OG7
C4B63_31g85 ⚠
iron superoxide dismutase A, mitochondrial
— OG7
C4B63_157g19 ⚠
eukaryotic translation initiation factor 4E (
— OG7
C4B63_13g189 ⚠
ubiquitin-like protein
— OG7
C4B63_112g17 ⚠
conserved hypothetical protein
— OG7
C4B63_46g15 ⚠
Kinesin-13 5
— OG7
C4B63_30g144 ⚠
Cilia- and flagella-associated protein 52
— Both
C4B63_4g383 ⚠
mevalonate-diphosphate decarboxylase
— Both
C4B63_175g8 ⚠
TPR-repeat protein
— OG6
C4B63_184g9 ⚠
protein phosphatase 2C
— OG6
C4B63_188g43 ⚠
conserved hypothetical protein
— Both
C4B63_11g25 ⚠
conserved hypothetical protein
— Both
C4B63_20g213 ⚠
enoyl-CoA hydratase/isomerase family protein
— Both
C4B63_246g7 ⚠
Gastrulation defective protein 1 homolog
— Both
C4B63_14g17 ⚠
small G-protein
— OG6
C4B63_10g147 ⚠
carnitine O-acetyltransferase(fragment)
— OG6
C4B63_4g357 ⚠
Activator of 90 kDa heat shock protein ATPase
— Both
C4B63_35g191 ⚠
6-phosphogluconolactonase
— Both
C4B63_4g136 ⚠
N-myristoyl transferase
— Both
C4B63_69g27
35 kDa cyclophilin
— OG6
C4B63_69g61 ⚠
Kinesin-13 1
— OG7
C4B63_44g235 ⚠
Kinesin-13 4
— OG7
C4B63_144g30 ⚠
Kinesin-13 1
— OG7
C4B63_9g331 ⚠
transcription elongation factor s-II
— Both
C4B63_279g8 ⚠
ubiquitin carboxyl-terminal hydrolase
— Both
C4B63_44g252 ⚠
ubiquitin carboxyl-terminal hydrolase
— Both
C4B63_114g23 ⚠
UBX domain-containing protein 3
— Both
C4B63_30g145 ⚠
electron-transfer-flavoprotein, alpha polypep
— Both
C4B63_16g163 ⚠
Pyridoxal phosphate homeostasis protein
— Both
C4B63_58g37 ⚠
conserved hypothetical protein
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.