C4B63_246g7

Gastrulation defective protein 1 homolog
Trypanosoma cruzi Dm28c 2018 OG6: OG6_144639 OG7: OG7_0007242 185 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 185 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_44g235 ⚠
Kinesin-13 4
— OG7
C4B63_42g174 ⚠
conserved hypothetical protein
— Both
C4B63_14g25 ⚠
small G-protein
— OG6
C4B63_14g17 ⚠
small G-protein
— OG6
C4B63_63g46 ⚠
2,3-bisphosphoglycerate-independent phosphogl
— Both
C4B63_23g34 ⚠
quinone oxidoreductase
— Both
C4B63_35g125 ⚠
transaldolase
— Both
C4B63_6g572 ⚠
5'-3' exoribonuclease A
— Both
C4B63_3g494 ⚠
Mucin-associated surface protein (MASP)
— OG6
C4B63_3g241 ⚠
mucin TcMUC
— OG6
C4B63_48g116 ⚠
5'-3' exoribonuclease D
— Both
C4B63_3g686 ⚠
Mucin-associated surface protein (MASP)
— OG6
C4B63_125g66 ⚠
Mucin-associated surface protein (MASP)
— OG6
C4B63_42g62 ⚠
dTDP-glucose 4,6-dehydratase
— Both
C4B63_9g488 ⚠
conserved hypothetical protein
— Both
C4B63_2g94 ⚠
conserved hypothetical protein
— Both
C4B63_12g20 ⚠
2-oxoglutarate-dependent dioxygenase tropC
— Both
C4B63_18g278 ⚠
RNA-binding protein
— OG6
C4B63_253g15 ⚠
haloacid dehalogenase-like hydrolase
— Both
C4B63_54g69 ⚠
aspartate aminotransferase
— Both
C4B63_6g146 ⚠
haloacid dehalogenase-like hydrolase
— Both
C4B63_28g64 ⚠
aspartate aminotransferase
— Both
C4B63_6g148 ⚠
haloacid dehalogenase-like hydrolase
— Both
C4B63_10g148 ⚠
carnitine/choline acetyltransferase
— OG6
C4B63_10g147 ⚠
carnitine O-acetyltransferase(fragment)
— OG6
C4B63_17g73 ⚠
Probable protein phosphatase methylesterase 1
— Both
C4B63_18g30 ⚠
epsilon-adaptin
— Both
C4B63_297g19 ⚠
Protein phosphatase methylesterase 1
— Both
C4B63_7g59 ⚠
protein phosphatase 2C
— OG6
C4B63_7g58 ⚠
protein phosphatase 2C
— OG6
C4B63_7g361 ⚠
phosphomannomutase-like protein
— Both
C4B63_17g188 ⚠
Phosphopantetheine adenylyltransferase
— Both
C4B63_30g144 ⚠
Cilia- and flagella-associated protein 52
— Both
C4B63_30g145 ⚠
electron-transfer-flavoprotein, alpha polypep
— Both
C4B63_16g163 ⚠
Pyridoxal phosphate homeostasis protein
— Both
C4B63_114g23 ⚠
UBX domain-containing protein 3
— Both
C4B63_23g200 ⚠
Flagellum attachment zone protein 19
— Both
C4B63_6g385 ⚠
tRNA threonylcarbamoyl adenosine modification
— Both
C4B63_230g26 ⚠
tRNA threonylcarbamoyl adenosine modification
— Both
C4B63_69g27 ⚠
35 kDa cyclophilin
— OG6
C4B63_14g183 ⚠
mitochondrial intermediate peptidase
— Both
C4B63_44g252 ⚠
ubiquitin carboxyl-terminal hydrolase
— Both
C4B63_279g8 ⚠
ubiquitin carboxyl-terminal hydrolase
— Both
C4B63_9g331 ⚠
transcription elongation factor s-II
— Both
C4B63_23g248 ⚠
inorganic pyrophosphatase
— Both
C4B63_70g77 ⚠
acidocalcisomal pyrophosphatase
— Both
C4B63_144g30 ⚠
Kinesin-13 1
— OG7
C4B63_7g383 ⚠
epsilon-adaptin
— OG7
C4B63_9g482 ⚠
Cid1 family poly A polymerase
— OG7
C4B63_87g11 ⚠
epsilon-adaptin(fragment)
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.