C4B63_14g183

mitochondrial intermediate peptidase
Trypanosoma cruzi Dm28c 2018 OG6: OG6_102110 OG7: OG7_0002961 106 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 106 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_2g443 ⚠
UDP-N-acetylglucosamine pyrophosphorylase
— Both
C4B63_6g234 ⚠
Elongation factor G 2, mitochondrial
— OG7
C4B63_51g115 ⚠
Proliferation-associated protein 2G4
— OG7
C4B63_183g15 ⚠
spermidine synthase
— OG7
C4B63_6g161 ⚠
Eukaryotic initiation factor 4A-1
— OG7
C4B63_49g176 ⚠
serine/threonine protein phosphatase
— OG7
C4B63_47g33 ⚠
malate dehydrogenase
— OG7
C4B63_4g68 ⚠
metallo-peptidase, Clan MG, Family M24
— OG7
C4B63_10g491 ⚠
conserved hypothetical protein
— OG7
C4B63_163g21 ⚠
deoxyribose-phosphate aldolase
— OG7
C4B63_2g396 ⚠
conserved hypothetical protein
— OG7
C4B63_128g65 ⚠
prolyl oligopeptidase
— OG7
C4B63_63g37 ⚠
oligopeptidase b(fragment)
— OG7
C4B63_128g64 ⚠
oligopeptidase b(fragment)
— OG7
C4B63_6g564 ⚠
oligopeptidase B-like protein
— OG7
C4B63_63g36 ⚠
prolyl endopeptidase
— OG7
C4B63_122g16 ⚠
oligopeptidase b
— OG7
C4B63_128g66 ⚠
oligopeptidase b(fragment)
— OG7
C4B63_253g15 ⚠
haloacid dehalogenase-like hydrolase
— OG7
C4B63_6g146 ⚠
haloacid dehalogenase-like hydrolase
— OG7
C4B63_6g148 ⚠
haloacid dehalogenase-like hydrolase
— OG7
C4B63_1g121c ⚠
cytochrome b5-like protein
— OG7
C4B63_45g127 ⚠
phosphoacetylglucosamine mutase
— OG7
C4B63_26g289 ⚠
myo-inositol-1 phosphatase
— OG7
C4B63_8g211 ⚠
cytochrome b
— OG7
C4B63_6g395 ⚠
Elongation factor G 2, mitochondrial
— OG7
C4B63_31g264 ⚠
aspartate carbamoyltransferase
— OG7
C4B63_39g336 ⚠
S-adenosylhomocysteine hydrolase
— OG7
C4B63_35g155 ⚠
aspartate carbamoyltransferase
— OG7
C4B63_27g180 ⚠
ATP-dependent protease ATPase subunit HslU2
— OG7
C4B63_42g63 ⚠
adenosine kinase
— OG7
C4B63_7g332 ⚠
adenosine kinase
— OG7
C4B63_348g23 ⚠
cytochrome b5
— OG7
C4B63_18g286 ⚠
conserved hypothetical protein
— OG7
C4B63_25g1526c ⚠
Acyl-lipid (8-3)-desaturase
— OG7
C4B63_30g290 ⚠
mercaptopyruvate sulfurtransferase
— OG7
C4B63_2g419 ⚠
UDP-galactose 4-epimerase
— OG7
C4B63_10g403 ⚠
cytochrome b5
— OG7
C4B63_134g60 ⚠
aspartate carbamoyltransferase
— OG7
C4B63_7g236 ⚠
regulatory subunit of protein kinase a-like p
— OG7
C4B63_32g236 ⚠
transketolase
— OG7
C4B63_80g15 ⚠
cAMP response protein 1
— OG7
C4B63_34g372 ⚠
cytochrome b-domain protein
— OG7
C4B63_11g26 ⚠
Xaa-Pro aminopeptidase
— OG7
C4B63_11g40 ⚠
urocanate hydratase
— OG7
C4B63_282g13 ⚠
Elongation factor G 2, mitochondrial
— OG7
C4B63_60g116 ⚠
aspartate carbamoyltransferase
— OG7
C4B63_51g192 ⚠
protein kinase A regulatory subunit
— OG7
C4B63_63g81 ⚠
protein transport protein Sec23A
— OG7
C4B63_42g180 ⚠
nitrate reductase
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.