C4B63_51g115

Proliferation-associated protein 2G4
Trypanosoma cruzi Dm28c 2018 OG6: OG6_146697 OG7: OG7_0006554 90 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 90 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_183g15 ⚠
spermidine synthase
— OG7
C4B63_6g161 ⚠
Eukaryotic initiation factor 4A-1
— OG7
C4B63_85g83 ⚠
Eukaryotic initiation factor 4A-1
— OG7
C4B63_63g53 ⚠
conserved hypothetical protein
— OG7
C4B63_54g24 ⚠
ATP-dependent DEAD/H RNA helicase
— OG7
C4B63_2g443 ⚠
UDP-N-acetylglucosamine pyrophosphorylase
— OG7
C4B63_43g161 ⚠
ATP-dependent RNA helicase SUB2
— OG7
C4B63_19g259 ⚠
conserved hypothetical protein
— OG7
C4B63_4g486 ⚠
glycosomal malate dehydrogenase
— OG7
C4B63_13g189 ⚠
ubiquitin-like protein
— OG7
C4B63_47g34 ⚠
mitochondrial malate dehydrogenase
— OG7
C4B63_87g38 ⚠
protein phosphatase 2A, regulatory subunit B
— OG7
C4B63_47g33 ⚠
malate dehydrogenase
— OG7
C4B63_38g147 ⚠
spermidine synthase
— OG7
C4B63_38g167 ⚠
spermidine synthase
— OG7
C4B63_163g21 ⚠
deoxyribose-phosphate aldolase
— OG7
C4B63_30g261 ⚠
deoxyribose-phosphate aldolase
— OG7
C4B63_95g55
ubiquitin-like protein
— OG6
C4B63_233g19 ⚠
ribosomal protein L15
— Both
C4B63_75g49 ⚠
ribosomal protein L15
— Both
C4B63_18g176 ⚠
ribosomal protein L15
— Both
C4B63_30g190 ⚠
60S ribosomal protein L23a
— Both
C4B63_102g85 ⚠
60S ribosomal protein L9
— Both
C4B63_8g202 ⚠
GTP-binding protein
— OG7
C4B63_2g527 ⚠
proteasome regulatory non-ATPase subunit 3
— OG7
C4B63_124g1 ⚠
phosphatidylinositol 3-kinase
— OG7
C4B63_17g277 ⚠
phosphatidylinositol 3-related kinase
— OG7
C4B63_2g431 ⚠
GTPase protein
— OG7
C4B63_4g355 ⚠
60S ribosomal protein L7
— OG7
C4B63_17g278 ⚠
phosphatidylinositol 3-related kinase
— OG7
C4B63_22g113 ⚠
phosphatidylinositol 3-kinase
— OG7
C4B63_56g32 ⚠
GTPase
— OG7
C4B63_2g345 ⚠
GTP-binding protein
— OG7
C4B63_91g35 ⚠
GTPase
— OG7
C4B63_168g34 ⚠
60S ribosomal protein L9
— Both
C4B63_7g380 ⚠
phosphatidylinositol 3-kinase(fragment)
— OG7
C4B63_124g3 ⚠
phosphatidylinositol 3-kinase
— OG7
C4B63_34g361 ⚠
phosphatidylinositol kinase related protein
— OG7
C4B63_124g2 ⚠
phosphatidylinositol 3-kinase
— OG7
C4B63_49g176 ⚠
serine/threonine protein phosphatase
— OG7
C4B63_44g171 ⚠
serine/threonine protein kinase
— OG7
C4B63_62g82 ⚠
thimet oligopeptidase
— OG7
C4B63_37g366 ⚠
thimet oligopeptidase
— OG7
C4B63_14g183 ⚠
mitochondrial intermediate peptidase
— OG7
C4B63_10g491 ⚠
conserved hypothetical protein
— OG7
C4B63_7g243 ⚠
ribosomal protein L3
— Both
C4B63_7g424 ⚠
phosphatidylinositol 3-kinase(fragment)
— Both
C4B63_20g33 ⚠
mitochondrial DNA polymerase I protein A
— OG6
C4B63_14g71 ⚠
conserved hypothetical protein
— Both
C4B63_395g1 ⚠
SLACS reverse transcriptase (fragment)
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.