C4B63_14g71

conserved hypothetical protein

Trypanosoma cruzi Dm28c 2018 OG6: OG6_158318 OG7: OG7_0051921 64 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 64 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
C4B63_40g94 conserved hypothetical protein	—	OG6 TCSYLVIO_004685 ↔ TCSYLVIO_008227 OG7 TCSYLVIO_004685 ↔ TCSYLVIO_008227	Both
C4B63_20g33 ⚠ mitochondrial DNA polymerase I protein A	—	OG6 TCSYLVIO_004685 ↔ TCSYLVIO_009363	OG6
C4B63_38g87 ⚠ 60S ribosomal protein L10	—	OG6 TCSYLVIO_004685 ↔ TCSYLVIO_007173 OG7 TCSYLVIO_004685 ↔ TCSYLVIO_007173	Both
C4B63_8g555 ⚠ 60S ribosomal protein L7	—	OG6 TCSYLVIO_004685 ↔ TCSYLVIO_009166 OG7 TCSYLVIO_004685 ↔ TCSYLVIO_009166	Both
C4B63_13g34 ⚠ 21 kDa cyclophilin	—	OG6 TCSYLVIO_004685 ↔ TCSYLVIO_007607	OG6
C4B63_4g145 nuclear segregation protein	—	OG6 TCSYLVIO_004685 ↔ TCSYLVIO_006132 OG7 TCSYLVIO_004685 ↔ TCSYLVIO_006132	Both
C4B63_8g556 ⚠ 60S ribosomal protein L7	—	OG6 TCSYLVIO_004685 ↔ TCSYLVIO_009166 OG7 TCSYLVIO_004685 ↔ TCSYLVIO_009166	Both
C4B63_45g76 ⚠ 60S ribosomal protein L7a	—	OG6 TCSYLVIO_004685 ↔ TCSYLVIO_009765 OG7 TCSYLVIO_004685 ↔ TCSYLVIO_009765	Both
C4B63_19g183 ⚠ cyclophilin a	—	OG6 TCSYLVIO_004685 ↔ TCSYLVIO_007607	OG6
C4B63_10g492 conserved hypothetical protein	—	OG6 TCSYLVIO_004685 ↔ TCSYLVIO_010706 OG7 TCSYLVIO_004685 ↔ TCSYLVIO_010706	Both
C4B63_128g62 ⚠ 50S ribosome-binding GTPase	—	OG6 TCSYLVIO_004685 ↔ TCSYLVIO_009877 OG7 TCSYLVIO_004685 ↔ TCSYLVIO_009877	Both
C4B63_128g61 ⚠ 50S ribosome-binding GTPase	—	OG6 TCSYLVIO_004685 ↔ TCSYLVIO_009877 OG7 TCSYLVIO_004685 ↔ TCSYLVIO_009877	Both
C4B63_45g97 eukaryotic translation initiation factor 3 su	—	OG6 TCSYLVIO_004685 ↔ TCSYLVIO_009752 OG7 TCSYLVIO_004685 ↔ TCSYLVIO_009752	Both
C4B63_38g68 ⚠ 60S ribosomal protein L10	—	OG6 TCSYLVIO_004685 ↔ TCSYLVIO_007173 OG7 TCSYLVIO_004685 ↔ TCSYLVIO_007173	Both
C4B63_14g192 ⚠ PSP1 C-terminal conserved region	—	OG6 TCSYLVIO_004685 ↔ TCSYLVIO_004769	OG6
C4B63_2g768 RNA-binding protein	—	OG6 TCSYLVIO_004685 ↔ TCSYLVIO_005823 OG7 TCSYLVIO_004685 ↔ TCSYLVIO_005823	Both
C4B63_220g13 ⚠ cyclophilin	—	OG6 TCSYLVIO_004685 ↔ TCSYLVIO_007607	OG6
C4B63_22g113 ⚠ phosphatidylinositol 3-kinase	—	OG7 TCSYLVIO_004639 ↔ TCSYLVIO_004685	OG7
C4B63_124g2 ⚠ phosphatidylinositol 3-kinase	—	OG7 TCSYLVIO_004639 ↔ TCSYLVIO_004685	OG7
C4B63_34g361 ⚠ phosphatidylinositol kinase related protein	—	OG7 TCSYLVIO_004639 ↔ TCSYLVIO_004685	OG7
C4B63_124g3 ⚠ phosphatidylinositol 3-kinase	—	OG7 TCSYLVIO_004639 ↔ TCSYLVIO_004685	OG7
C4B63_7g380 ⚠ phosphatidylinositol 3-kinase(fragment)	—	OG7 TCSYLVIO_004639 ↔ TCSYLVIO_004685	OG7
C4B63_17g278 ⚠ phosphatidylinositol 3-related kinase	—	OG7 TCSYLVIO_004639 ↔ TCSYLVIO_004685	OG7
C4B63_17g277 ⚠ phosphatidylinositol 3-related kinase	—	OG7 TCSYLVIO_004639 ↔ TCSYLVIO_004685	OG7
C4B63_124g1 ⚠ phosphatidylinositol 3-kinase	—	OG7 TCSYLVIO_004639 ↔ TCSYLVIO_004685	OG7
C4B63_8g202 ⚠ GTP-binding protein	—	OG7 TCSYLVIO_004685 ↔ TCSYLVIO_009877	OG7
C4B63_91g35 ⚠ GTPase	—	OG7 TCSYLVIO_004685 ↔ TCSYLVIO_009877	OG7
C4B63_2g345 ⚠ GTP-binding protein	—	OG7 TCSYLVIO_004685 ↔ TCSYLVIO_009877	OG7
C4B63_56g32 ⚠ GTPase	—	OG7 TCSYLVIO_004685 ↔ TCSYLVIO_009877	OG7
C4B63_4g355 ⚠ 60S ribosomal protein L7	—	OG7 TCSYLVIO_004685 ↔ TCSYLVIO_009166	OG7
C4B63_2g431 ⚠ GTPase protein	—	OG7 TCSYLVIO_004685 ↔ TCSYLVIO_009877	OG7
C4B63_4g68 ⚠ metallo-peptidase, Clan MG, Family M24	—	OG7 TCSYLVIO_002064 ↔ TCSYLVIO_004685	OG7
C4B63_233g19 ⚠ ribosomal protein L15	—	OG6 TCSYLVIO_001077 ↔ TCSYLVIO_004685 OG7 TCSYLVIO_001077 ↔ TCSYLVIO_004685	Both
C4B63_63g101 ⚠ Phosphatidylinositol 3-kinase tor1	—	OG6 TCSYLVIO_004639 ↔ TCSYLVIO_004685 OG7 TCSYLVIO_004639 ↔ TCSYLVIO_004685	Both
C4B63_51g115 ⚠ Proliferation-associated protein 2G4	—	OG6 TCSYLVIO_002064 ↔ TCSYLVIO_004685 OG7 TCSYLVIO_002064 ↔ TCSYLVIO_004685	Both
C4B63_20g321 ⚠ 60S ribosomal protein L13a	—	OG6 TCSYLVIO_003971 ↔ TCSYLVIO_004685 OG7 TCSYLVIO_003971 ↔ TCSYLVIO_004685	Both
C4B63_83g62 ⚠ 60S ribosomal protein L13a	—	OG6 TCSYLVIO_003971 ↔ TCSYLVIO_004685 OG7 TCSYLVIO_003971 ↔ TCSYLVIO_004685	Both
C4B63_395g1 ⚠ SLACS reverse transcriptase (fragment)	—	OG6 TCSYLVIO_001814 ↔ TCSYLVIO_004685 OG6 TCSYLVIO_004685 ↔ TCSYLVIO_009094	OG6
C4B63_30g166 ⚠ 60S ribosomal protein L19	—	OG6 TCSYLVIO_001814 ↔ TCSYLVIO_004685 OG6 TCSYLVIO_004685 ↔ TCSYLVIO_009094 OG7 TCSYLVIO_001814 ↔ TCSYLVIO_004685 OG7 TCSYLVIO_004685 ↔ TCSYLVIO_009094	Both
C4B63_143g25 ⚠ 60S ribosomal protein L19	—	OG6 TCSYLVIO_001814 ↔ TCSYLVIO_004685 OG6 TCSYLVIO_004685 ↔ TCSYLVIO_009094 OG7 TCSYLVIO_001814 ↔ TCSYLVIO_004685 OG7 TCSYLVIO_004685 ↔ TCSYLVIO_009094	Both
C4B63_143g27 ⚠ 60S ribosomal protein L19	—	OG6 TCSYLVIO_001814 ↔ TCSYLVIO_004685 OG6 TCSYLVIO_004685 ↔ TCSYLVIO_009094 OG7 TCSYLVIO_001814 ↔ TCSYLVIO_004685 OG7 TCSYLVIO_004685 ↔ TCSYLVIO_009094	Both
C4B63_30g170 ⚠ 60S ribosomal protein L19	—	OG6 TCSYLVIO_001814 ↔ TCSYLVIO_004685 OG6 TCSYLVIO_004685 ↔ TCSYLVIO_009094 OG7 TCSYLVIO_001814 ↔ TCSYLVIO_004685 OG7 TCSYLVIO_004685 ↔ TCSYLVIO_009094	Both
C4B63_30g168 ⚠ 60S ribosomal protein L19	—	OG6 TCSYLVIO_001814 ↔ TCSYLVIO_004685 OG6 TCSYLVIO_004685 ↔ TCSYLVIO_009094 OG7 TCSYLVIO_001814 ↔ TCSYLVIO_004685 OG7 TCSYLVIO_004685 ↔ TCSYLVIO_009094	Both
C4B63_23g197 ⚠ 60S ribosomal protein L13	—	OG6 TCSYLVIO_004413 ↔ TCSYLVIO_004685 OG7 TCSYLVIO_004413 ↔ TCSYLVIO_004685	Both
C4B63_30g190 60S ribosomal protein L23a	—	OG6 TCSYLVIO_001829 ↔ TCSYLVIO_004685 OG7 TCSYLVIO_001829 ↔ TCSYLVIO_004685	Both
C4B63_23g196 ⚠ 60S ribosomal protein L13	—	OG6 TCSYLVIO_004413 ↔ TCSYLVIO_004685 OG7 TCSYLVIO_004413 ↔ TCSYLVIO_004685	Both
C4B63_18g176 ⚠ ribosomal protein L15	—	OG6 TCSYLVIO_001077 ↔ TCSYLVIO_004685 OG7 TCSYLVIO_001077 ↔ TCSYLVIO_004685	Both
C4B63_75g49 ⚠ ribosomal protein L15	—	OG6 TCSYLVIO_001077 ↔ TCSYLVIO_004685 OG7 TCSYLVIO_001077 ↔ TCSYLVIO_004685	Both
C4B63_7g424 ⚠ phosphatidylinositol 3-kinase(fragment)	—	OG6 TCSYLVIO_004639 ↔ TCSYLVIO_004685 OG7 TCSYLVIO_004639 ↔ TCSYLVIO_004685	Both
C4B63_43g4 ⚠ 60S ribosomal protein L9	—	OG6 TCSYLVIO_003366 ↔ TCSYLVIO_004685 OG7 TCSYLVIO_003366 ↔ TCSYLVIO_004685	Both

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