C4B63_38g68

60S ribosomal protein L10

Trypanosoma cruzi Dm28c 2018 OG6: OG6_100701 OG7: OG7_0004941 104 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Interactions 104 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
C4B63_102g85 ⚠ 60S ribosomal protein L9	—	OG6 TCSYLVIO_003366 ↔ TCSYLVIO_007173 OG6 Tb927.10.1100 ↔ Tb927.9.8420 OG7 TCSYLVIO_003366 ↔ TCSYLVIO_007173 OG7 Tb927.10.1100 ↔ Tb927.9.8420	Both
C4B63_168g34 ⚠ 60S ribosomal protein L9	—	OG6 TCSYLVIO_003366 ↔ TCSYLVIO_007173 OG6 Tb927.10.1100 ↔ Tb927.9.8420 OG7 TCSYLVIO_003366 ↔ TCSYLVIO_007173 OG7 Tb927.10.1100 ↔ Tb927.9.8420	Both
C4B63_18g144 ⚠ 60S ribosomal protein L9	—	OG6 TCSYLVIO_003366 ↔ TCSYLVIO_007173 OG6 Tb927.10.1100 ↔ Tb927.9.8420 OG7 TCSYLVIO_003366 ↔ TCSYLVIO_007173 OG7 Tb927.10.1100 ↔ Tb927.9.8420	Both
C4B63_43g4 ⚠ 60S ribosomal protein L9	—	OG6 TCSYLVIO_003366 ↔ TCSYLVIO_007173 OG6 Tb927.10.1100 ↔ Tb927.9.8420 OG7 TCSYLVIO_003366 ↔ TCSYLVIO_007173 OG7 Tb927.10.1100 ↔ Tb927.9.8420	Both
C4B63_20g321 ⚠ 60S ribosomal protein L13a	—	OG6 TCSYLVIO_003971 ↔ TCSYLVIO_007173 OG6 Tb927.5.1610 ↔ Tb927.9.8420 OG7 Tb927.5.1610 ↔ Tb927.9.8420 OG7 TCSYLVIO_003971 ↔ TCSYLVIO_007173	Both
C4B63_83g62 ⚠ 60S ribosomal protein L13a	—	OG6 TCSYLVIO_003971 ↔ TCSYLVIO_007173 OG6 Tb927.5.1610 ↔ Tb927.9.8420 OG7 Tb927.5.1610 ↔ Tb927.9.8420 OG7 TCSYLVIO_003971 ↔ TCSYLVIO_007173	Both
C4B63_23g196 ⚠ 60S ribosomal protein L13	—	OG6 TCSYLVIO_004413 ↔ TCSYLVIO_007173 OG6 Tb927.3.3310 ↔ Tb927.9.8070 OG7 TCSYLVIO_004413 ↔ TCSYLVIO_007173 OG7 Tb927.3.3310 ↔ Tb927.9.8070	Both
C4B63_23g197 ⚠ 60S ribosomal protein L13	—	OG6 TCSYLVIO_004413 ↔ TCSYLVIO_007173 OG6 Tb927.3.3310 ↔ Tb927.9.8070 OG7 TCSYLVIO_004413 ↔ TCSYLVIO_007173 OG7 Tb927.3.3310 ↔ Tb927.9.8070	Both
C4B63_395g1 ⚠ SLACS reverse transcriptase (fragment)	—	OG6 TCSYLVIO_001814 ↔ TCSYLVIO_007173 OG6 Tb927.7.5020 ↔ Tb927.9.8420 OG6 Tb927.7.5000 ↔ Tb927.9.8070 OG6 TCSYLVIO_007173 ↔ TCSYLVIO_009094	OG6
C4B63_30g166 ⚠ 60S ribosomal protein L19	—	OG6 TCSYLVIO_001814 ↔ TCSYLVIO_007173 OG6 Tb927.7.5020 ↔ Tb927.9.8420 OG6 Tb927.7.5000 ↔ Tb927.9.8070 OG6 TCSYLVIO_007173 ↔ TCSYLVIO_009094 +4 more	Both
C4B63_143g25 ⚠ 60S ribosomal protein L19	—	OG6 TCSYLVIO_001814 ↔ TCSYLVIO_007173 OG6 Tb927.7.5020 ↔ Tb927.9.8420 OG6 Tb927.7.5000 ↔ Tb927.9.8070 OG6 TCSYLVIO_007173 ↔ TCSYLVIO_009094 +4 more	Both
C4B63_143g27 ⚠ 60S ribosomal protein L19	—	OG6 TCSYLVIO_001814 ↔ TCSYLVIO_007173 OG6 Tb927.7.5020 ↔ Tb927.9.8420 OG6 Tb927.7.5000 ↔ Tb927.9.8070 OG6 TCSYLVIO_007173 ↔ TCSYLVIO_009094 +4 more	Both
C4B63_30g170 ⚠ 60S ribosomal protein L19	—	OG6 TCSYLVIO_001814 ↔ TCSYLVIO_007173 OG6 Tb927.7.5020 ↔ Tb927.9.8420 OG6 Tb927.7.5000 ↔ Tb927.9.8070 OG6 TCSYLVIO_007173 ↔ TCSYLVIO_009094 +4 more	Both
C4B63_30g168 ⚠ 60S ribosomal protein L19	—	OG6 TCSYLVIO_001814 ↔ TCSYLVIO_007173 OG6 Tb927.7.5020 ↔ Tb927.9.8420 OG6 Tb927.7.5000 ↔ Tb927.9.8070 OG6 TCSYLVIO_007173 ↔ TCSYLVIO_009094 +4 more	Both
C4B63_13g269 ⚠ 40S ribosomal protein S9	—	OG6 Tb927.10.5610 ↔ Tb927.9.8070 OG7 Tb927.10.5610 ↔ Tb927.9.8070	Both
C4B63_12g209 ⚠ 60S ribosomal protein L24	—	OG7 Tb927.10.5460 ↔ Tb927.9.8070	OG7
C4B63_170g19 ⚠ 40S ribosomal protein S4	—	OG6 Tb927.11.3600 ↔ Tb927.9.8420 OG6 Tb927.11.3590 ↔ Tb927.9.8070 OG7 Tb927.11.3600 ↔ Tb927.9.8420 OG7 Tb927.11.3590 ↔ Tb927.9.8070	Both
C4B63_170g22 ⚠ 40S ribosomal protein S4	—	OG6 Tb927.11.3600 ↔ Tb927.9.8420 OG6 Tb927.11.3590 ↔ Tb927.9.8070 OG7 Tb927.11.3600 ↔ Tb927.9.8420 OG7 Tb927.11.3590 ↔ Tb927.9.8070	Both
C4B63_170g18 ⚠ 40S ribosomal protein S4	—	OG6 Tb927.11.3600 ↔ Tb927.9.8420 OG6 Tb927.11.3590 ↔ Tb927.9.8070 OG7 Tb927.11.3600 ↔ Tb927.9.8420 OG7 Tb927.11.3590 ↔ Tb927.9.8070	Both
C4B63_170g20 ⚠ 40S ribosomal protein S4	—	OG6 Tb927.11.3600 ↔ Tb927.9.8420 OG6 Tb927.11.3590 ↔ Tb927.9.8070 OG7 Tb927.11.3600 ↔ Tb927.9.8420 OG7 Tb927.11.3590 ↔ Tb927.9.8070	Both
C4B63_170g17 ⚠ 40S ribosomal protein S4	—	OG6 Tb927.11.3600 ↔ Tb927.9.8420 OG6 Tb927.11.3590 ↔ Tb927.9.8070 OG7 Tb927.11.3600 ↔ Tb927.9.8420 OG7 Tb927.11.3590 ↔ Tb927.9.8070	Both
C4B63_46g76 ⚠ 40S ribosomal protein S4	—	OG6 Tb927.11.3600 ↔ Tb927.9.8420 OG6 Tb927.11.3590 ↔ Tb927.9.8070 OG7 Tb927.11.3600 ↔ Tb927.9.8420 OG7 Tb927.11.3590 ↔ Tb927.9.8070	Both
C4B63_170g21 ⚠ 40S ribosomal protein S4	—	OG6 Tb927.11.3600 ↔ Tb927.9.8420 OG6 Tb927.11.3590 ↔ Tb927.9.8070 OG7 Tb927.11.3600 ↔ Tb927.9.8420 OG7 Tb927.11.3590 ↔ Tb927.9.8070	Both
C4B63_46g77 ⚠ 40S ribosomal protein S4	—	OG6 Tb927.11.3600 ↔ Tb927.9.8420 OG6 Tb927.11.3590 ↔ Tb927.9.8070 OG7 Tb927.11.3600 ↔ Tb927.9.8420 OG7 Tb927.11.3590 ↔ Tb927.9.8070	Both
C4B63_14g71 ⚠ conserved hypothetical protein	—	OG6 TCSYLVIO_004685 ↔ TCSYLVIO_007173 OG7 TCSYLVIO_004685 ↔ TCSYLVIO_007173	Both
C4B63_18g223 ⚠ eukaryotic translation initiation factor 3 su	—	OG6 TCSYLVIO_003333 ↔ TCSYLVIO_007173 OG7 TCSYLVIO_003333 ↔ TCSYLVIO_007173	Both
C4B63_128g63 ⚠ GTP-binding protein	—	OG6 TCSYLVIO_007173 ↔ TCSYLVIO_009877 OG7 TCSYLVIO_007173 ↔ TCSYLVIO_009877	Both
C4B63_45g75 ⚠ 60S ribosomal protein L7a	—	OG6 TCSYLVIO_007173 ↔ TCSYLVIO_009765 OG7 TCSYLVIO_007173 ↔ TCSYLVIO_009765	Both
C4B63_149g20 ⚠ cyclophilin	—	OG6 TCSYLVIO_007173 ↔ TCSYLVIO_007607	OG6
C4B63_43g142 ⚠ mitochondrial structure specific endonuclease	—	OG6 TCSYLVIO_007173 ↔ TCSYLVIO_009363 OG7 TCSYLVIO_007173 ↔ TCSYLVIO_009363	Both
C4B63_220g13 ⚠ cyclophilin	—	OG6 TCSYLVIO_007173 ↔ TCSYLVIO_007607	OG6
C4B63_20g33 ⚠ mitochondrial DNA polymerase I protein A	—	OG6 TCSYLVIO_007173 ↔ TCSYLVIO_009363	OG6
C4B63_8g555 ⚠ 60S ribosomal protein L7	—	OG6 TCSYLVIO_007173 ↔ TCSYLVIO_009166 OG7 TCSYLVIO_007173 ↔ TCSYLVIO_009166	Both
C4B63_13g34 ⚠ 21 kDa cyclophilin	—	OG6 TCSYLVIO_007173 ↔ TCSYLVIO_007607	OG6
C4B63_7g380 ⚠ phosphatidylinositol 3-kinase(fragment)	—	OG7 TCSYLVIO_004639 ↔ TCSYLVIO_007173	OG7
C4B63_2g691 ⚠ 30S Ribosomal protein S17	—	OG6 Tb927.10.560 ↔ Tb927.9.8070 OG7 Tb927.10.560 ↔ Tb927.9.8070	Both
C4B63_7g366 ⚠ ribosomal protein L14	—	OG7 Tb927.9.11410 ↔ Tb927.9.8420	OG7
C4B63_4g68 ⚠ metallo-peptidase, Clan MG, Family M24	—	OG7 TCSYLVIO_002064 ↔ TCSYLVIO_007173	OG7
C4B63_2g431 ⚠ GTPase protein	—	OG7 TCSYLVIO_007173 ↔ TCSYLVIO_009877	OG7
C4B63_4g355 ⚠ 60S ribosomal protein L7	—	OG7 TCSYLVIO_007173 ↔ TCSYLVIO_009166	OG7
C4B63_56g32 ⚠ GTPase	—	OG7 TCSYLVIO_007173 ↔ TCSYLVIO_009877	OG7
C4B63_2g345 ⚠ GTP-binding protein	—	OG7 TCSYLVIO_007173 ↔ TCSYLVIO_009877	OG7
C4B63_91g35 ⚠ GTPase	—	OG7 TCSYLVIO_007173 ↔ TCSYLVIO_009877	OG7
C4B63_8g202 ⚠ GTP-binding protein	—	OG7 TCSYLVIO_007173 ↔ TCSYLVIO_009877	OG7
C4B63_124g1 ⚠ phosphatidylinositol 3-kinase	—	OG7 TCSYLVIO_004639 ↔ TCSYLVIO_007173	OG7
C4B63_17g277 ⚠ phosphatidylinositol 3-related kinase	—	OG7 TCSYLVIO_004639 ↔ TCSYLVIO_007173	OG7
C4B63_17g278 ⚠ phosphatidylinositol 3-related kinase	—	OG7 TCSYLVIO_004639 ↔ TCSYLVIO_007173	OG7
C4B63_10g492 ⚠ conserved hypothetical protein	—	OG6 TCSYLVIO_007173 ↔ TCSYLVIO_010706 OG7 TCSYLVIO_007173 ↔ TCSYLVIO_010706	Both
C4B63_128g61 ⚠ 50S ribosome-binding GTPase	—	OG6 TCSYLVIO_007173 ↔ TCSYLVIO_009877 OG7 TCSYLVIO_007173 ↔ TCSYLVIO_009877	Both
C4B63_128g62 ⚠ 50S ribosome-binding GTPase	—	OG6 TCSYLVIO_007173 ↔ TCSYLVIO_009877 OG7 TCSYLVIO_007173 ↔ TCSYLVIO_009877	Both

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