C4B63_4g68

metallo-peptidase, Clan MG, Family M24
Trypanosoma cruzi Dm28c 2018 OG6: OG6_101895 OG7: OG7_0006554 85 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 85 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_2g345 ⚠
GTP-binding protein
— OG7
C4B63_43g142 ⚠
mitochondrial structure specific endonuclease
— OG7
C4B63_20g321 ⚠
60S ribosomal protein L13a
— OG7
C4B63_23g196 ⚠
60S ribosomal protein L13
— OG7
C4B63_7g243 ⚠
ribosomal protein L3
— OG7
C4B63_7g242 ⚠
ribosomal protein L3
— OG7
C4B63_7g245 ⚠
ribosomal protein L3
— OG7
C4B63_45g75 ⚠
60S ribosomal protein L7a
— OG7
C4B63_63g101 ⚠
Phosphatidylinositol 3-kinase tor1
— OG7
C4B63_43g4 ⚠
60S ribosomal protein L9
— OG7
C4B63_128g63 ⚠
GTP-binding protein
— OG7
C4B63_56g32 ⚠
GTPase
— OG7
C4B63_91g35 ⚠
GTPase
— OG7
C4B63_23g197 ⚠
60S ribosomal protein L13
— OG7
C4B63_8g556 ⚠
60S ribosomal protein L7
— OG7
C4B63_8g202 ⚠
GTP-binding protein
— OG7
C4B63_4g145 ⚠
nuclear segregation protein
— OG7
C4B63_8g555 ⚠
60S ribosomal protein L7
— OG7
C4B63_7g380 ⚠
phosphatidylinositol 3-kinase(fragment)
— OG7
C4B63_38g87 ⚠
60S ribosomal protein L10
— OG7
C4B63_7g424 ⚠
phosphatidylinositol 3-kinase(fragment)
— OG7
C4B63_124g3 ⚠
phosphatidylinositol 3-kinase
— OG7
C4B63_38g68 ⚠
60S ribosomal protein L10
— OG7
C4B63_102g85 ⚠
60S ribosomal protein L9
— OG7
C4B63_168g34 ⚠
60S ribosomal protein L9
— OG7
C4B63_40g94 ⚠
conserved hypothetical protein
— OG7
C4B63_124g1 ⚠
phosphatidylinositol 3-kinase
— OG7
C4B63_17g277 ⚠
phosphatidylinositol 3-related kinase
— OG7
C4B63_83g62 ⚠
60S ribosomal protein L13a
— OG7
C4B63_7g241 ⚠
ribosomal protein L3
— OG7
C4B63_2g431 ⚠
GTPase protein
— OG7
C4B63_2g768 ⚠
RNA-binding protein
— OG7
C4B63_4g355 ⚠
60S ribosomal protein L7
— OG7
C4B63_34g361 ⚠
phosphatidylinositol kinase related protein
— OG7
C4B63_45g97 ⚠
eukaryotic translation initiation factor 3 su
— OG7
C4B63_128g61 ⚠
50S ribosome-binding GTPase
— OG7
C4B63_128g62 ⚠
50S ribosome-binding GTPase
— OG7
C4B63_10g492 ⚠
conserved hypothetical protein
— OG7
C4B63_7g244 ⚠
ribosomal protein L3
— OG7
C4B63_45g76 ⚠
60S ribosomal protein L7a
— OG7
C4B63_17g278 ⚠
phosphatidylinositol 3-related kinase
— OG7
C4B63_22g113 ⚠
phosphatidylinositol 3-kinase
— OG7
C4B63_18g144 ⚠
60S ribosomal protein L9
— OG7
C4B63_2g443 ⚠
UDP-N-acetylglucosamine pyrophosphorylase
— Both
C4B63_30g168 ⚠
60S ribosomal protein L19
— OG7
C4B63_30g170 ⚠
60S ribosomal protein L19
— OG7
C4B63_30g166 ⚠
60S ribosomal protein L19
— OG7
C4B63_143g27 ⚠
60S ribosomal protein L19
— OG7
C4B63_143g25 ⚠
60S ribosomal protein L19
— OG7
C4B63_30g274 ⚠
rac serine-threonine kinase
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.