C4B63_2g768

RNA-binding protein
Trypanosoma cruzi Dm28c 2018 OG6: OG6_146722 OG7: OG7_0043663 183 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 183 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_8g202 ⚠
GTP-binding protein
— OG7
C4B63_7g79 ⚠
aspartyl-tRNA synthetase
— Both
C4B63_2g5
casein kinase II
— OG6
C4B63_14g71
conserved hypothetical protein
— Both
C4B63_319g2 ⚠
conserved hypothetical protein
— Both
C4B63_2g297
conserved hypothetical protein
— Both
C4B63_48g166 ⚠
serine/cysteine trypsin-like peptidase
— Both
C4B63_192g1 ⚠
serine/cysteine trypsin-like peptidase
— Both
C4B63_40g132 ⚠
conserved hypothetical protein
— Both
C4B63_319g1 ⚠
conserved hypothetical protein
— Both
C4B63_4g258
prolyl-tRNA synthetase
— Both
C4B63_69g26
endo-beta-N-acetylglucosaminidase
— Both
C4B63_2g376 ⚠
ribosome assembly protein RRB1
— Both
C4B63_12g211 ⚠
conserved hypothetical protein
— Both
C4B63_12g212 ⚠
conserved hypothetical protein
— Both
C4B63_31g99
WD repeat-containing protein 17
— Both
C4B63_142g11 ⚠
Protein shuttle craft
— Both
C4B63_12g208
leucine-rich repeat protein (LRRP)
— Both
C4B63_10g293
Phosphatidylinositol 4-phosphate 5-kinase 6
— OG6
C4B63_6g400 ⚠
conserved hypothetical protein
— Both
C4B63_282g21 ⚠
conserved hypothetical protein
— Both
C4B63_173g6 ⚠
Soluble NSF attachment protein, SNAP (parafla
— Both
C4B63_34g375 ⚠
Soluble NSF attachment protein, SNAP (parafla
— Both
C4B63_4g235 ⚠
5-oxoprolinase
— Both
C4B63_4g234 ⚠
5-oxoprolinase
— Both
C4B63_9g322
translation initiation factor IF-2
— Both
C4B63_38g40
Reticulocyte-binding protein 2 homolog a
— Both
C4B63_2g450 ⚠
metallo-peptidase, Clan MF, Family M17
— OG7
C4B63_7g388 ⚠
geranylgeranyl transferase type II beta subun
— OG7
C4B63_6g517 ⚠
geranylgeranyl transferase type II beta subun
— OG7
C4B63_24g301
phosphatidylinositol-4-phosphate 5-kinase
— OG7
C4B63_22g113 ⚠
phosphatidylinositol 3-kinase
— OG7
C4B63_124g2 ⚠
phosphatidylinositol 3-kinase
— OG7
C4B63_22g108 ⚠
Replication Factor C Subunit 1-related protei
— OG7
C4B63_2g762 ⚠
replication factor C, subunit 3
— OG7
C4B63_34g361 ⚠
phosphatidylinositol kinase related protein
— OG7
C4B63_124g3 ⚠
phosphatidylinositol 3-kinase
— OG7
C4B63_7g380 ⚠
phosphatidylinositol 3-kinase(fragment)
— OG7
C4B63_17g278 ⚠
phosphatidylinositol 3-related kinase
— OG7
C4B63_17g277 ⚠
phosphatidylinositol 3-related kinase
— OG7
C4B63_124g1 ⚠
phosphatidylinositol 3-kinase
— OG7
C4B63_61g82 ⚠
Chromosome transmission fidelity protein 18 h
— OG7
C4B63_18g277 ⚠
replication factor C, subunit 2
— OG7
C4B63_61g81 ⚠
conserved hypothetical protein
— OG7
C4B63_63g41 ⚠
replication factor C, subunit 3
— OG7
C4B63_39g340 ⚠
replication factor C, subunit 4
— OG7
C4B63_57g94 ⚠
ATP-dependent RNA helicase
— OG7
C4B63_44g232 ⚠
CRAL/TRIO domain containing protein
— OG7
C4B63_54g82
conserved hypothetical protein
— OG7
C4B63_359g23 ⚠
CRAL/TRIO domain containing protein
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.