C4B63_2g5

casein kinase II
Trypanosoma cruzi Dm28c 2018 OG6: OG6_100821 OG7: OG7_0000396 95 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 95 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_40g133 ⚠
Casein kinase II subunit beta
— OG6
C4B63_319g3 ⚠
Casein kinase II subunit beta
— OG6
C4B63_14g93
Cyclin 12, L-type
— OG6
C4B63_12g211 ⚠
conserved hypothetical protein
— OG6
C4B63_6g322 ⚠
conserved hypothetical protein
— OG6
C4B63_137g49 ⚠
conserved hypothetical protein
— OG6
C4B63_4g258
prolyl-tRNA synthetase
— OG6
C4B63_26g231 ⚠
ubiquitin hydrolase(fragment)
— OG6
C4B63_192g3 ⚠
AAA ATPase
— OG6
C4B63_26g232 ⚠
ubiquitin hydrolase(fragment)
— OG6
C4B63_48g168 ⚠
AAA ATPase
— OG6
C4B63_2g768
RNA-binding protein
— OG6
C4B63_101g26
conserved hypothetical protein
— OG6
C4B63_192g1 ⚠
serine/cysteine trypsin-like peptidase
— OG6
C4B63_12g212 ⚠
conserved hypothetical protein
— OG6
C4B63_14g81 ⚠
conserved hypothetical protein
— OG6
C4B63_48g166 ⚠
serine/cysteine trypsin-like peptidase
— OG6
C4B63_14g79 ⚠
conserved hypothetical protein
— OG6
C4B63_13g240
conserved hypothetical protein
— OG6
C4B63_14g80 ⚠
conserved hypothetical protein
— OG6
C4B63_2g750
death-receptor fusion protein (DUF2428)
— OG6
C4B63_7g79
aspartyl-tRNA synthetase
— OG6
C4B63_300g17 ⚠
E3 ubiquitin-protein ligase MGRN1
— OG6
C4B63_34g319 ⚠
E3 ubiquitin-protein ligase MGRN1
— OG6
C4B63_134g35 ⚠
ubiquitin hydrolase
— OG6
C4B63_18g156
protein mkt1
— OG6
C4B63_9g322
translation initiation factor IF-2
— OG6
C4B63_49g160 ⚠
ATP-dependent DEAD/H RNA helicase
— OG6
C4B63_293g23 ⚠
ATP-dependent DEAD/H RNA helicase(fragment)
— OG6
C4B63_293g24 ⚠
ATP-dependent DEAD/H RNA helicase(fragment)
— OG6
C4B63_293g21 ⚠
ATP-dependent DEAD/H RNA helicase(fragment)
— OG6
C4B63_293g22 ⚠
ATP-dependent DEAD/H RNA helicase(fragment)
— OG6
C4B63_85g46
Ring finger domain/Zn-finger in ubiquitin-hyd
— OG6
C4B63_26g275
protein phosphatase 2A regulatory subunit
— OG6
C4B63_4g234 ⚠
5-oxoprolinase
— OG6
C4B63_4g235 ⚠
5-oxoprolinase
— OG6
C4B63_102g62 ⚠
conserved hypothetical protein
— OG6
C4B63_35g128 ⚠
ubiquitin hydrolase
— OG6
C4B63_34g375 ⚠
Soluble NSF attachment protein, SNAP (parafla
— OG6
C4B63_173g6 ⚠
Soluble NSF attachment protein, SNAP (parafla
— OG6
C4B63_282g21 ⚠
conserved hypothetical protein
— OG6
C4B63_6g400 ⚠
conserved hypothetical protein
— OG6
C4B63_10g293
Phosphatidylinositol 4-phosphate 5-kinase 6
— OG6
C4B63_12g208
leucine-rich repeat protein (LRRP)
— OG6
C4B63_142g11
Protein shuttle craft
— OG6
C4B63_31g99
WD repeat-containing protein 17
— OG6
C4B63_31g177 ⚠
ribonuclease Z
— OG6
C4B63_31g178 ⚠
Zinc phosphodiesterase ELAC protein 2
— OG6
C4B63_8g219 ⚠
protein farnesyltransferase
— OG6
C4B63_292g17 ⚠
translation-associated element 2
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.