C4B63_38g167

spermidine synthase
Trypanosoma cruzi Dm28c 2018 OG6: OG6_100634 OG7: OG7_0003460 62 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
Applies on "Apply filters".
Reset
⬇ CSV
Network view all shared interactors, plus up to 150 more
Show:

Selection: Shift+drag also box-selects. Drag any selected node to move the whole selection.
Interactions 62 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_47g33 ⚠
malate dehydrogenase
— OG7
C4B63_4g486 ⚠
glycosomal malate dehydrogenase
— OG7
C4B63_47g34 ⚠
mitochondrial malate dehydrogenase
— Both
C4B63_44g171 ⚠
serine/threonine protein kinase
— OG7
C4B63_54g24 ⚠
ATP-dependent DEAD/H RNA helicase
— OG7
C4B63_63g46 ⚠
2,3-bisphosphoglycerate-independent phosphogl
— Both
C4B63_6g394 ⚠
ribose 5-phosphate isomerase type B
— Both
C4B63_282g12 ⚠
ribose 5-phosphate isomerase type B
— Both
C4B63_20g6 ⚠
D-isomer specific 2-hydroxyacid dehydrogenase
— Both
C4B63_7g161 ⚠
D-isomer specific 2-hydroxyacid dehydrogenase
— Both
C4B63_7g169 ⚠
D-isomer specific 2-hydroxyacid dehydrogenase
— Both
C4B63_7g173 ⚠
D-isomer specific 2-hydroxyacid dehydrogenase
— Both
C4B63_7g157 ⚠
D-isomer specific 2-hydroxyacid dehydrogenase
— Both
C4B63_20g1 ⚠
D-isomer specific 2-hydroxyacid dehydrogenase
— Both
C4B63_20g3 ⚠
D-isomer specific 2-hydroxyacid dehydrogenase
— Both
C4B63_7g165 ⚠
D-isomer specific 2-hydroxyacid dehydrogenase
— Both
C4B63_20g10 ⚠
D-isomer specific 2-hydroxyacid dehydrogenase
— Both
C4B63_20g11 ⚠
D-isomer specific 2-hydroxyacid dehydrogenase
— Both
C4B63_63g53 ⚠
conserved hypothetical protein
— OG7
C4B63_85g83 ⚠
Eukaryotic initiation factor 4A-1
— OG7
C4B63_51g115 ⚠
Proliferation-associated protein 2G4
— OG7
C4B63_6g161 ⚠
Eukaryotic initiation factor 4A-1
— OG7
C4B63_49g176 ⚠
serine/threonine protein phosphatase
— OG7
C4B63_10g491 ⚠
conserved hypothetical protein
— OG7
C4B63_9g333 ⚠
cysteine peptidase, Clan CA, family C51
— OG7
C4B63_106g2 ⚠
cysteine peptidase, Clan CA, family C51
— OG7
C4B63_314g6 ⚠
trypanothione synthetase
— OG7
C4B63_106g1 ⚠
cysteine peptidase, Clan CA, family C51
— OG7
C4B63_9g335 ⚠
cysteine peptidase, Clan CA, family C51
— OG7
C4B63_16g7 ⚠
trypanothione synthetase
— OG7
C4B63_11g491 ⚠
trypanothione synthetase
— OG7
C4B63_14g183 ⚠
mitochondrial intermediate peptidase
— OG7
C4B63_4g68 ⚠
metallo-peptidase, Clan MG, Family M24
— Both
C4B63_9g263 ⚠
trypanothione synthetase
— Both
C4B63_8g510 ⚠
conserved hypothetical protein
— Both
C4B63_23g234 ⚠
inosine-adenosine-guanosine-nucleosidehydrola
— Both
C4B63_20g361 ⚠
uracil phosphoribosyltransferase
— Both
C4B63_17g82 ⚠
ubiquitin-conjugating enzyme E2
— Both
C4B63_30g187 ⚠
deoxyuridine triphosphatase
— Both
C4B63_133g46 ⚠
cytosolic malate dehydrogenase
— Both
C4B63_43g161 ⚠
ATP-dependent RNA helicase SUB2
— Both
C4B63_2g443 ⚠
UDP-N-acetylglucosamine pyrophosphorylase
— Both
C4B63_87g38 ⚠
protein phosphatase 2A, regulatory subunit B
— Both
C4B63_163g32 ⚠
rac serine-threonine kinase
— OG6
C4B63_30g261 ⚠
deoxyribose-phosphate aldolase
— Both
C4B63_11g488 ⚠
rac serine-threonine kinase(fragment)
— OG6
C4B63_76g48 ⚠
peptidyl-prolyl cis-trans isomerase
— OG6
C4B63_42g103 ⚠
pyridoxal kinase
— Both
C4B63_163g21 ⚠
deoxyribose-phosphate aldolase
— Both
C4B63_30g274 ⚠
rac serine-threonine kinase
— OG6
Page 1 of 2
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.