C4B63_9g335

cysteine peptidase, Clan CA, family C51
Trypanosoma cruzi Dm28c 2018 OG6: OG6_115782 OG7: OG7_0010828 66 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 66 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_8g483 ⚠
asparagine synthetase a
— OG7
C4B63_10g288 ⚠
Paraflagellar rod protein 2
— OG7
C4B63_183g15 ⚠
spermidine synthase
— OG7
C4B63_47g115 ⚠
fatty acyl CoA synthetase
— OG7
C4B63_85g53 ⚠
fatty acyl CoA synthetase 2
— OG7
C4B63_38g147 ⚠
spermidine synthase
— OG7
C4B63_38g167 ⚠
spermidine synthase
— OG7
C4B63_85g54 ⚠
fatty acyl CoA synthetase 2
— OG7
C4B63_42g103 ⚠
pyridoxal kinase
— OG7
C4B63_23g234 ⚠
inosine-adenosine-guanosine-nucleosidehydrola
— OG7
C4B63_30g187 ⚠
deoxyuridine triphosphatase
— OG7
C4B63_10g287 ⚠
Paraflagellar rod protein 2
— OG7
C4B63_70g95 ⚠
14-3-3 protein 2
— OG7
C4B63_39g344 ⚠
14-3-3 protein 1
— OG7
C4B63_94g47 ⚠
thymidylate kinase
— OG7
C4B63_21g234 ⚠
thymidylate kinase
— OG7
C4B63_122g4 ⚠
UPF0160 protein C27H6.8
— OG7
C4B63_9g266 ⚠
paraflagellar rod protein 5
— OG7
C4B63_16g17 ⚠
acetyl-CoA synthetase
— OG7
C4B63_11g10 ⚠
KIF1-binding protein
— OG7
C4B63_122g20 ⚠
ribonucleoside-diphosphate reductase small ch
— OG7
C4B63_27g3 ⚠
ribonucleoside-diphosphate reductase small ch
— OG7
C4B63_69g26 ⚠
endo-beta-N-acetylglucosaminidase
— OG7
C4B63_63g46 ⚠
2,3-bisphosphoglycerate-independent phosphogl
— OG7
C4B63_30g193 ⚠
Phosphoethanolamine/phosphocholine phosphatas
— OG7
C4B63_10g291 ⚠
Paraflagellar rod protein 2
— OG7
C4B63_2g208c ⚠
aminopeptidase P
— OG7
C4B63_10g289 ⚠
Paraflagellar rod protein 2
— OG7
C4B63_9g267 ⚠
paraflagellar rod protein 5
— OG7
C4B63_10g290 ⚠
Paraflagellar rod protein 2
— OG7
C4B63_85g51 ⚠
fatty acyl CoA syntetase 1
— OG7
C4B63_85g55 ⚠
fatty acyl CoA syntetase 1
— OG7
C4B63_25g317 ⚠
threonine synthase
— OG7
C4B63_206g21 ⚠
fatty acyl CoA synthetase
— OG7
C4B63_28g106 ⚠
malic enzyme
— OG7
C4B63_47g34 ⚠
mitochondrial malate dehydrogenase
— OG7
C4B63_47g33 ⚠
malate dehydrogenase
— OG7
C4B63_133g46 ⚠
cytosolic malate dehydrogenase
— OG7
C4B63_38g165 ⚠
conserved hypothetical protein
— OG7
C4B63_60g174 ⚠
adenylate kinase
— OG7
C4B63_35g190 ⚠
histone chaperone ASF1B
— OG7
C4B63_90g46 ⚠
cysteine synthase
— OG7
C4B63_40g159 ⚠
translation initiation factor 2 subunit
— OG7
C4B63_28g107 ⚠
malic enzyme
— OG7
C4B63_128g65 ⚠
prolyl oligopeptidase
— OG7
C4B63_2g77 ⚠
aminopeptidase P
— OG7
C4B63_63g37 ⚠
oligopeptidase b(fragment)
— OG7
C4B63_4g331 ⚠
tubulin-specific chaperone
— OG7
C4B63_43g196 ⚠
adenylate kinase 1
— OG7
C4B63_275g17 ⚠
UPF0160 protein C27H6.8
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.