C4B63_23g234

inosine-adenosine-guanosine-nucleosidehydrolase
Trypanosoma cruzi Dm28c 2018 OG6: OG6_124384 OG7: OG7_0003875 36 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
Applies on "Apply filters".
Reset
⬇ CSV
Network view all shared interactors, plus up to 150 more
Show:

Selection: Shift+drag also box-selects. Drag any selected node to move the whole selection.
Interactions 36 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_4g486 ⚠
glycosomal malate dehydrogenase
— OG7
C4B63_133g46
cytosolic malate dehydrogenase
— Both
C4B63_47g34 ⚠
mitochondrial malate dehydrogenase
— Both
C4B63_11g262 ⚠
gamma-glutamylcysteine synthetase
— Both
C4B63_116g18 ⚠
gamma-glutamylcysteine synthetase
— Both
C4B63_27g3 ⚠
ribonucleoside-diphosphate reductase small ch
— Both
C4B63_122g20 ⚠
ribonucleoside-diphosphate reductase small ch
— Both
C4B63_49g79
WD domain, G-beta repeat
— Both
C4B63_63g46
2,3-bisphosphoglycerate-independent phosphogl
— Both
C4B63_221g23 ⚠
SET domain containing protein
— OG6
C4B63_47g33 ⚠
malate dehydrogenase
— OG7
C4B63_9g333 ⚠
cysteine peptidase, Clan CA, family C51
— OG7
C4B63_106g2 ⚠
cysteine peptidase, Clan CA, family C51
— OG7
C4B63_314g6 ⚠
trypanothione synthetase
— OG7
C4B63_106g1 ⚠
cysteine peptidase, Clan CA, family C51
— OG7
C4B63_9g335 ⚠
cysteine peptidase, Clan CA, family C51
— OG7
C4B63_16g7 ⚠
trypanothione synthetase
— OG7
C4B63_11g491 ⚠
trypanothione synthetase
— OG7
C4B63_42g103
pyridoxal kinase
— Both
C4B63_38g167 ⚠
spermidine synthase
— Both
C4B63_38g147 ⚠
spermidine synthase
— Both
C4B63_31g265 ⚠
dihydroorotate dehydrogenase
— Both
C4B63_85g53 ⚠
fatty acyl CoA synthetase 2
— Both
C4B63_35g156 ⚠
dihydroorotate dehydrogenase
— Both
C4B63_47g115 ⚠
fatty acyl CoA synthetase
— Both
C4B63_183g15 ⚠
spermidine synthase
— Both
C4B63_134g61 ⚠
dihydroorotate dehydrogenase
— Both
C4B63_9g263 ⚠
trypanothione synthetase
— Both
C4B63_60g117 ⚠
dihydroorotate dehydrogenase
— Both
C4B63_85g54 ⚠
fatty acyl CoA synthetase 2
— Both
C4B63_8g483
asparagine synthetase a
— Both
C4B63_206g21 ⚠
fatty acyl CoA synthetase
— Both
C4B63_25g317
threonine synthase
— Both
C4B63_85g55 ⚠
fatty acyl CoA syntetase 1
— Both
C4B63_85g51 ⚠
fatty acyl CoA syntetase 1
— Both
C4B63_16g282 ⚠
SET domain containing protein
— OG6
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.