C4B63_7g332

adenosine kinase
Trypanosoma cruzi Dm28c 2018 OG6: OG6_100649 OG7: OG7_0004747 60 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 60 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_2g810 ⚠
aminotransferase
— OG7
C4B63_19g185 ⚠
isocitrate dehydrogenase
— OG7
C4B63_54g23 ⚠
enoyl-CoA hydratase/isomerase family protein
— OG7
C4B63_14g183 ⚠
mitochondrial intermediate peptidase
— OG7
C4B63_282g13 ⚠
Elongation factor G 2, mitochondrial
— OG7
C4B63_39g304 ⚠
NUDIX hydrolase 3
— OG7
C4B63_2g443 ⚠
UDP-N-acetylglucosamine pyrophosphorylase
— OG7
C4B63_2g522 ⚠
choline kinase
— OG7
C4B63_63g81 ⚠
protein transport protein Sec23A
— OG7
C4B63_10g494 ⚠
thymine-7-hydroxylase
— OG7
C4B63_84g37 ⚠
Gastrulation defective protein 1 homolog
— OG7
C4B63_17g263 ⚠
phosphomannose isomerase
— OG7
C4B63_40g22 ⚠
CRAL/TRIO domain containing protein
— OG7
C4B63_17g118 ⚠
SEC14-like protein 5
— OG7
C4B63_26g204 ⚠
phosphomevalonate kinase protein
— OG7
C4B63_6g234 ⚠
Elongation factor G 2, mitochondrial
— OG7
C4B63_37g366 ⚠
thimet oligopeptidase
— OG7
C4B63_12g20 ⚠
2-oxoglutarate-dependent dioxygenase tropC
— OG7
C4B63_3g1118 ⚠
choline/ethanolamine kinase
— OG7
C4B63_17g264 ⚠
phosphomannose isomerase
— OG7
C4B63_246g7 ⚠
Gastrulation defective protein 1 homolog
— OG7
C4B63_11g76 ⚠
molecular chaperone HscB
— OG7
C4B63_4g357 ⚠
Activator of 90 kDa heat shock protein ATPase
— OG7
C4B63_4g189 ⚠
alcohol dehydrogenase
— OG7
C4B63_25g252 ⚠
myo-inositol-1(or 4)-monophosphatase 1
— OG7
C4B63_27g180 ⚠
ATP-dependent protease ATPase subunit HslU2
— OG7
C4B63_83g29 ⚠
ATP-dependent protease ATPase subunit HslU1
— OG7
C4B63_80g17 ⚠
ATP binding protein-like protein
— OG7
C4B63_9g220 ⚠
Thioredoxin domain-containing protein PLP3A
— OG7
C4B63_72g86 ⚠
EEF1A lysine methyltransferase 4
— OG7
C4B63_49g136 ⚠
Putative glutathione-specific gamma-glutamylc
— OG7
C4B63_29g6 ⚠
EEF1A lysine methyltransferase 4
— Both
C4B63_42g242 ⚠
2-hydroxy-3-oxopropionate reductase
— Both
C4B63_24g191 ⚠
deoxyhypusine hydroxylase
— Both
C4B63_27g229 ⚠
cyclin 1
— Both
C4B63_13g193 ⚠
cytosolic factor SEC14
— Both
C4B63_90g55 ⚠
TPR-repeat protein(fragment)
— Both
C4B63_79g87 ⚠
phosphoglucomutase
— Both
C4B63_22g69 ⚠
serine/threonine protein phosphatase 2A regul
— Both
C4B63_23g240 ⚠
Eukaryotic translation initiation factor 2 su
— Both
C4B63_20g212 ⚠
enoyl-CoA hydratase/isomerase family protein
— Both
C4B63_20g213 ⚠
enoyl-CoA hydratase/isomerase family protein
— Both
C4B63_35g125 ⚠
transaldolase
— Both
C4B63_6g510 ⚠
Zinc finger MYND domain-containing protein 10
— Both
C4B63_114g23 ⚠
UBX domain-containing protein 3
— OG7
C4B63_33g10 ⚠
EEF1A lysine methyltransferase 4
— Both
C4B63_12g21 ⚠
Uncharacterized oxidoreductase YkwC
— OG7
C4B63_2g94 ⚠
conserved hypothetical protein
— OG7
C4B63_21g261 ⚠
isocitrate dehydrogenase [NADP], mitochondria
— OG7
C4B63_132g66 ⚠
NUDIX hydrolase 3
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.