C4B63_22g69

serine/threonine protein phosphatase 2A regulatory subunit
Trypanosoma cruzi Dm28c 2018 OG6: OG6_101100 OG7: OG7_0004752 53 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 53 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_2g833 ⚠
Probable C-terminal domain small phosphatase
— OG7
C4B63_18g286
conserved hypothetical protein
— Both
C4B63_227g2 ⚠
glucan 1,3-alpha-glucosidase
— Both
C4B63_4g375 ⚠
glucan 1,3-alpha-glucosidase
— Both
C4B63_18g214
S-adenosylmethionine decarboxylase proenzyme
— Both
C4B63_6g444
phosphonopyruvate decarboxylase
— Both
C4B63_2g747 ⚠
MTR3
— Both
C4B63_18g153
T-complex protein 11
— Both
C4B63_113g64
conserved hypothetical protein
— Both
C4B63_6g510 ⚠
Zinc finger MYND domain-containing protein 10
— Both
C4B63_16g162
conserved hypothetical protein
— Both
C4B63_17g119 ⚠
Phosphatidylinositol/phosphatidylcholine tran
— OG7
C4B63_18g39 ⚠
CRAL/TRIO, N-terminal domain/CRAL/TRIO domain
— OG7
C4B63_2g726 ⚠
CRAL/TRIO domain containing protein
— OG7
C4B63_18g157
DNA ligase I
— Both
C4B63_11g24 ⚠
TFIIF-stimulated CTD phosphatase
— OG7
C4B63_40g22 ⚠
CRAL/TRIO domain containing protein
— OG7
C4B63_17g118 ⚠
SEC14-like protein 5
— OG7
C4B63_48g7 ⚠
NLI interacting factor-like phosphatase
— OG7
C4B63_23g189 ⚠
Uncharacterized protein C2F7.02c
— OG7
C4B63_63g31 ⚠
Carboxy-terminal domain RNA polymerase II pol
— OG7
C4B63_301g7 ⚠
conserved hypothetical protein
— OG7
C4B63_12g21 ⚠
Uncharacterized oxidoreductase YkwC
— OG7
C4B63_40g73 ⚠
glycosyl hydrolase-like protein
— OG7
C4B63_28g37 ⚠
Cap-specific mRNA (nucleoside-2'-O-)-methyltr
— OG7
C4B63_42g62 ⚠
dTDP-glucose 4,6-dehydratase
— OG7
C4B63_72g86 ⚠
EEF1A lysine methyltransferase 4
— OG7
C4B63_7g332 ⚠
adenosine kinase
— Both
C4B63_27g229
cyclin 1
— Both
C4B63_33g10 ⚠
EEF1A lysine methyltransferase 4
— Both
C4B63_29g6 ⚠
EEF1A lysine methyltransferase 4
— Both
C4B63_20g29
conserved hypothetical protein
— Both
C4B63_24g191
deoxyhypusine hydroxylase
— Both
C4B63_84g34 ⚠
Tetratricopeptide repeat protein 4
— Both
C4B63_246g3 ⚠
Tetratricopeptide repeat protein 4
— Both
C4B63_12g290 ⚠
Peptide chain release factor 1, mitochondrial
— Both
C4B63_120g70 ⚠
Peptide chain release factor 1, mitochondrial
— Both
C4B63_30g214
conserved hypothetical protein
— Both
C4B63_23g240
Eukaryotic translation initiation factor 2 su
— Both
C4B63_42g242 ⚠
2-hydroxy-3-oxopropionate reductase
— Both
C4B63_27g188
conserved hypothetical protein
— Both
C4B63_42g63 ⚠
adenosine kinase
— Both
C4B63_23g268
Tubulin-specific chaperone E
— Both
C4B63_23g190
conserved hypothetical protein
— Both
C4B63_8g37
conserved hypothetical protein
— Both
C4B63_113g46
conserved hypothetical protein
— Both
C4B63_54g5 ⚠
TFIIF-stimulated CTD phosphatase
— Both
C4B63_6g214
2,3-bisphosphoglycerate-independent phosphogl
— Both
C4B63_13g193 ⚠
cytosolic factor SEC14
— Both
C4B63_90g55 ⚠
TPR-repeat protein(fragment)
— Both
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.