C4B63_72g86

EEF1A lysine methyltransferase 4
Trypanosoma cruzi Dm28c 2018 OG6: OG6_137290 OG7: OG7_0003453 47 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 47 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_22g69 ⚠
serine/threonine protein phosphatase 2A regul
— OG7
C4B63_2g83 ⚠
ubiquitin hydrolase
— OG7
C4B63_112g33 ⚠
haloacid dehalogenase hydrolase
— OG7
C4B63_30g112 ⚠
haloacid dehalogenase hydrolase
— OG7
C4B63_144g24 ⚠
monothiol glutaredoxin
— OG7
C4B63_42g242 ⚠
2-hydroxy-3-oxopropionate reductase
— OG7
C4B63_17g119 ⚠
Phosphatidylinositol/phosphatidylcholine tran
— OG7
C4B63_13g193 ⚠
cytosolic factor SEC14
— OG7
C4B63_12g21 ⚠
Uncharacterized oxidoreductase YkwC
— OG7
C4B63_90g55 ⚠
TPR-repeat protein(fragment)
— OG7
C4B63_18g39 ⚠
CRAL/TRIO, N-terminal domain/CRAL/TRIO domain
— OG7
C4B63_79g87 ⚠
phosphoglucomutase
— OG7
C4B63_80g25 ⚠
ubiquitin hydrolase
— OG7
C4B63_2g726 ⚠
CRAL/TRIO domain containing protein
— OG7
C4B63_7g332 ⚠
adenosine kinase
— OG7
C4B63_42g62 ⚠
dTDP-glucose 4,6-dehydratase
— OG7
C4B63_24g191 ⚠
deoxyhypusine hydroxylase
— OG7
C4B63_27g229 ⚠
cyclin 1
— OG7
C4B63_6g510 ⚠
Zinc finger MYND domain-containing protein 10
— OG7
C4B63_40g22 ⚠
CRAL/TRIO domain containing protein
— OG7
C4B63_17g118 ⚠
SEC14-like protein 5
— OG7
C4B63_63g33 ⚠
ATP synthase OSCP delta subunit-like protein
— OG7
C4B63_23g240 ⚠
Eukaryotic translation initiation factor 2 su
— OG7
C4B63_42g63 ⚠
adenosine kinase
— OG7
C4B63_55g27 ⚠
conserved hypothetical protein
— Both
C4B63_3g1086 ⚠
monothiol glutaredoxin
— Both
C4B63_14g782c ⚠
monothiol glutaredoxin
— Both
C4B63_99g106 ⚠
monothiol glutaredoxin
— Both
C4B63_33g10 ⚠
EEF1A lysine methyltransferase 4
— Both
C4B63_29g6 ⚠
EEF1A lysine methyltransferase 4
— Both
C4B63_59g203 ⚠
Mucin-associated surface protein (MASP)
— OG6
C4B63_139g39 ⚠
Mucin-associated surface protein (MASP)
— OG6
C4B63_28g118 ⚠
DNA polymerase theta
— Both
C4B63_36g194 ⚠
Mucin-associated surface protein (MASP)
— OG6
C4B63_32g13 ⚠
Putative calmodulin-like protein 2
— OG6
C4B63_253g15 ⚠
haloacid dehalogenase-like hydrolase
— Both
C4B63_7g133 ⚠
pyroglutamyl-peptidase I
— Both
C4B63_89g43 ⚠
PITH domain-containing protein
— Both
C4B63_59g225 ⚠
Mucin-associated surface protein (MASP)
— OG6
C4B63_38g153 ⚠
EF hand
— OG6
C4B63_6g146 ⚠
haloacid dehalogenase-like hydrolase
— Both
C4B63_2g502 ⚠
ubiquitin carboxyl-terminal hydrolase
— Both
C4B63_252g9 ⚠
ubiquitin carboxyl-terminal hydrolase
— Both
C4B63_6g148 ⚠
haloacid dehalogenase-like hydrolase
— Both
C4B63_55g26 ⚠
conserved hypothetical protein
— Both
C4B63_69g55 ⚠
monothiol glutaredoxin
— OG7
C4B63_20g33 ⚠
mitochondrial DNA polymerase I protein A
— OG7
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.