C4B63_24g191

deoxyhypusine hydroxylase
Trypanosoma cruzi Dm28c 2018 OG6: OG6_101312 OG7: OG7_0007797 175 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 175 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_69g61 ⚠
Kinesin-13 1
— OG7
C4B63_42g242 ⚠
2-hydroxy-3-oxopropionate reductase
— Both
C4B63_140g30 ⚠
diphthine synthase
— Both
C4B63_129g42 ⚠
diphthine synthase
— Both
C4B63_44g104 ⚠
diphthine synthase
— Both
C4B63_21g56
nucleoside phosphorylase
— Both
C4B63_28g91 ⚠
Kinesin-13 3
— Both
C4B63_28g98 ⚠
aldo/keto reductase
— Both
C4B63_7g332 ⚠
adenosine kinase
— Both
C4B63_42g63 ⚠
adenosine kinase
— Both
C4B63_8g539 ⚠
C-1-tetrahydrofolate synthase, cytoplasmic
— Both
C4B63_18g279 ⚠
C-1-tetrahydrofolate synthase, cytoplasmic
— OG6
C4B63_55g68 ⚠
conserved hypothetical protein
— Both
C4B63_55g69 ⚠
conserved hypothetical protein
— Both
C4B63_238g18 ⚠
GMP synthase(fragment)
— Both
C4B63_142g6 ⚠
GMP synthase
— Both
C4B63_42g174
conserved hypothetical protein
— Both
C4B63_35g125
transaldolase
— Both
C4B63_6g572 ⚠
5'-3' exoribonuclease A
— Both
C4B63_3g494 ⚠
Mucin-associated surface protein (MASP)
— OG6
C4B63_3g241 ⚠
mucin TcMUC
— OG6
C4B63_48g116 ⚠
5'-3' exoribonuclease D
— Both
C4B63_3g686 ⚠
Mucin-associated surface protein (MASP)
— OG6
C4B63_125g66 ⚠
Mucin-associated surface protein (MASP)
— OG6
C4B63_18g278
RNA-binding protein
— OG6
C4B63_253g15 ⚠
haloacid dehalogenase-like hydrolase
— Both
C4B63_54g69 ⚠
aspartate aminotransferase
— Both
C4B63_6g146 ⚠
haloacid dehalogenase-like hydrolase
— Both
C4B63_28g64 ⚠
aspartate aminotransferase
— Both
C4B63_6g148 ⚠
haloacid dehalogenase-like hydrolase
— Both
C4B63_18g30 ⚠
epsilon-adaptin
— Both
C4B63_30g144
Cilia- and flagella-associated protein 52
— Both
C4B63_114g23
UBX domain-containing protein 3
— Both
C4B63_16g163
Pyridoxal phosphate homeostasis protein
— Both
C4B63_30g145
electron-transfer-flavoprotein, alpha polypep
— Both
C4B63_6g385 ⚠
tRNA threonylcarbamoyl adenosine modification
— Both
C4B63_230g26 ⚠
tRNA threonylcarbamoyl adenosine modification
— Both
C4B63_69g27
35 kDa cyclophilin
— OG6
C4B63_6g510 ⚠
Zinc finger MYND domain-containing protein 10
— Both
C4B63_44g252 ⚠
ubiquitin carboxyl-terminal hydrolase
— Both
C4B63_279g8 ⚠
ubiquitin carboxyl-terminal hydrolase
— Both
C4B63_9g331 ⚠
transcription elongation factor s-II
— Both
C4B63_144g30 ⚠
Kinesin-13 1
— OG7
C4B63_44g235 ⚠
Kinesin-13 4
— OG7
C4B63_42g204 ⚠
Eukaryotic translation initiation factor 4E-4
— OG7
C4B63_17g118 ⚠
SEC14-like protein 5
— OG7
C4B63_23g122 ⚠
serine/threonine protein kinase
— OG7
C4B63_40g22 ⚠
CRAL/TRIO domain containing protein
— OG7
C4B63_13g231 ⚠
serine/threonine protein kinase
— OG7
C4B63_6g269 ⚠
Eukaryotic translation initiation factor 4E-4
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.