TCSYLVIO_010946

isocitrate dehydrogenase [NADP], mitochondrial precursor, putative
Trypanosoma cruzi Sylvio X10/1-2012 OG6: OG6_100639 OG7: OG7_0004251 Source organism 102 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
Cross-organism orthology
Defaulting to same-organism data. Applies on "Apply filters".
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Interactions 102 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TCSYLVIO_010701
hypothetical protein
T.cruzi_2025_Azimi — n/a
TCSYLVIO_006512
cyclin 1, putative,serine peptidase family S5
T.cruzi_2025_Azimi — n/a
TCSYLVIO_009212
phosphoenolpyruvate mutase, putative
T.cruzi_2025_Azimi — n/a
TCSYLVIO_008471
dihydroorotase, putative
T.cruzi_2025_Azimi — n/a
TCSYLVIO_000216
alanine racemase, putative
T.cruzi_2025_Azimi — n/a
TCSYLVIO_004608
2,3-bisphosphoglycerate-independent phosphogl
T.cruzi_2025_Azimi — n/a
TCSYLVIO_003852
protein phosphatase 2C, putative
T.cruzi_2025_Azimi — n/a
TCSYLVIO_005459
hypothetical protein
T.cruzi_2025_Azimi — n/a
TCSYLVIO_007000
hypothetical protein
T.cruzi_2025_Azimi — n/a
TCSYLVIO_004300
carnitine/choline acetyltransferase, putative
T.cruzi_2025_Azimi — n/a
TCSYLVIO_003734
phosphomannomutase-like protein, putative
T.cruzi_2025_Azimi — n/a
TCSYLVIO_001393
hypothetical protein
T.cruzi_2025_Azimi — n/a
TCSYLVIO_001163
hypothetical protein
T.cruzi_2025_Azimi — n/a
TCSYLVIO_003462
cyclophilin, putative
T.cruzi_2025_Azimi — n/a
TCSYLVIO_005535
eukaryotic translation initiation factor eIF-
T.cruzi_2025_Azimi — n/a
TCSYLVIO_010948
protein transport protein Sec23A, putative
T.cruzi_2025_Azimi — n/a
TCSYLVIO_010957
pyroglutamyl-peptidase I (PGP), putative,cyst
T.cruzi_2025_Azimi — n/a
TCSYLVIO_004559
hypothetical protein
T.cruzi_2025_Azimi — n/a
TCSYLVIO_002576
haloacid dehalogenase-like hydrolase, putativ
T.cruzi_2025_Azimi — n/a
TCSYLVIO_006133
pyruvate kinase 2, putative
T.cruzi_2025_Azimi — n/a
TCSYLVIO_009243
NUDIX hydrolase, putative
T.cruzi_2025_Azimi — n/a
TCSYLVIO_006201
alcohol dehydrogenase, putative
T.cruzi_2025_Azimi — n/a
TCSYLVIO_006126
N-myristoyl transferase, putative
T.cruzi_2025_Azimi — n/a
TCSYLVIO_005860
cysteine desulfurase, putative
T.cruzi_2025_Azimi — n/a
TCSYLVIO_002410
heat shock protein HslVU, ATPase subunit HslU
T.cruzi_2025_Azimi — n/a
TCSYLVIO_009926
stress-inducible protein STI1-like, putative
T.cruzi_2025_Azimi — n/a
TCSYLVIO_005923
hypothetical protein
T.cruzi_2025_Azimi — n/a
TCSYLVIO_000361
nucleoside phosphorylase, putative
T.cruzi_2025_Azimi — n/a
TCSYLVIO_004898
nicotinate phosphoribosyltransferase, putativ
T.cruzi_2025_Azimi — n/a
TCSYLVIO_004210
hypothetical protein
T.cruzi_2025_Azimi — n/a
TCSYLVIO_001112
transaldolase, putative
T.cruzi_2025_Azimi — n/a
TCSYLVIO_001538
aspartate aminotransferase, mitochondrial, pu
T.cruzi_2025_Azimi — n/a
TCSYLVIO_004145
phosphomannose isomerase, putative
T.cruzi_2025_Azimi — n/a
TCSYLVIO_003543
hypothetical protein
T.cruzi_2025_Azimi — n/a
TCSYLVIO_001147
GMP synthase, putative,glutamine amidotransfe
T.cruzi_2025_Azimi — n/a
TCSYLVIO_007482
protein phosphatase 2C, putative
T.cruzi_2025_Azimi — n/a
TCSYLVIO_000382
transcription elongation factor-like protein,
T.cruzi_2025_Azimi — n/a
TCSYLVIO_005564
UDP-sugar pyrophosphorylase
T.cruzi_2025_Azimi — n/a
TCSYLVIO_008398
retrotransposon hot spot (RHS) protein, putat
T.cruzi_2025_Azimi — n/a
TCSYLVIO_004489
quinone oxidoreductase, putative
T.cruzi_2025_Azimi — n/a
TCSYLVIO_005081
enoyl-CoA hydratase/isomerase family protein,
T.cruzi_2025_Azimi — n/a
TCSYLVIO_003130
hypothetical protein
T.cruzi_2025_Azimi — n/a
TCSYLVIO_006390
hypothetical protein
T.cruzi_2025_Azimi — n/a
TCSYLVIO_001023
hypothetical protein
T.cruzi_2025_Azimi — n/a
TCSYLVIO_004455
inorganic pyrophosphatase, putative
T.cruzi_2025_Azimi — n/a
TCSYLVIO_009989
eukaryotic translation initiation factor 6 (e
T.cruzi_2025_Azimi — n/a
TCSYLVIO_001783
hypothetical protein
T.cruzi_2025_Azimi — n/a
TCSYLVIO_001508
aldo/keto reductase, putative
T.cruzi_2025_Azimi — n/a
TCSYLVIO_004644
small G-protein, putative
T.cruzi_2025_Azimi — n/a
TCSYLVIO_007028
phosphomevalonate kinase protein, putative
T.cruzi_2025_Azimi — n/a
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.