C4B63_39g336

S-adenosylhomocysteine hydrolase
Trypanosoma cruzi Dm28c 2018 OG6: OG6_100715 OG7: OG7_0003269 66 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 66 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_295g26 ⚠
glutamate dehydrogenase
— Both
C4B63_19g169
protein phosphatase
— OG6
C4B63_9g293 ⚠
Mitochondrial-processing peptidase subunit al
— Both
C4B63_206g14 ⚠
delta-1-pyrroline-5-carboxylate dehydrogenase
— Both
C4B63_47g111 ⚠
delta-1-pyrroline-5-carboxylate dehydrogenase
— Both
C4B63_18g286
conserved hypothetical protein
— Both
C4B63_30g290
mercaptopyruvate sulfurtransferase
— Both
C4B63_2g419
UDP-galactose 4-epimerase
— Both
C4B63_2g765
cystathione gamma lyase
— Both
C4B63_34g372 ⚠
cytochrome b-domain protein
— OG7
C4B63_295g20 ⚠
tryparedoxin peroxidase
— Both
C4B63_26g206 ⚠
glutaminyl-tRNA synthetase
— Both
C4B63_7g347
V-type ATPase, A subunit
— Both
C4B63_295g18 ⚠
tryparedoxin peroxidase
— Both
C4B63_77g29 ⚠
(H+)-ATPase G subunit
— Both
C4B63_30g161 ⚠
glutamine synthetase
— Both
C4B63_295g16 ⚠
tryparedoxin peroxidase
— Both
C4B63_220g12 ⚠
peroxidoxin
— Both
C4B63_70g572c ⚠
cytochrome b5
— OG7
C4B63_1g121c ⚠
cytochrome b5-like protein
— OG7
C4B63_8g211 ⚠
cytochrome b
— OG7
C4B63_10g403 ⚠
cytochrome b5
— OG7
C4B63_25g1526c ⚠
Acyl-lipid (8-3)-desaturase
— OG7
C4B63_348g23 ⚠
cytochrome b5
— OG7
C4B63_80g15 ⚠
cAMP response protein 1
— OG7
C4B63_7g236 ⚠
regulatory subunit of protein kinase a-like p
— OG7
C4B63_58g112 ⚠
mitochondrial processing peptidase alpha subu
— OG7
C4B63_95g34 ⚠
mitochondrial processing peptidase alpha subu
— OG7
C4B63_14g147 ⚠
phosphoribosylpyrophosphate synthetase
— OG7
C4B63_31g109 ⚠
ribose-phosphate pyrophosphokinase
— OG7
C4B63_2g380 ⚠
phosphoribosylpyrophosphate synthetase
— OG7
C4B63_18g130 ⚠
glutamyl-tRNA synthetase
— OG7
C4B63_14g183 ⚠
mitochondrial intermediate peptidase
— OG7
C4B63_37g366 ⚠
thimet oligopeptidase
— Both
C4B63_12g221 ⚠
pyruvate phosphate dikinase
— Both
C4B63_12g220 ⚠
pyruvate phosphate dikinase
— Both
C4B63_51g192 ⚠
protein kinase A regulatory subunit
— Both
C4B63_6g257 ⚠
Vacuolar proton pump subunit B
— Both
C4B63_6g258 ⚠
Vacuolar proton pump subunit B
— Both
C4B63_39g357
ATP synthase
— Both
C4B63_11g40
urocanate hydratase
— Both
C4B63_11g26
Xaa-Pro aminopeptidase
— Both
C4B63_101g36 ⚠
inositol-3-phosphate synthase
— Both
C4B63_62g82 ⚠
thimet oligopeptidase
— Both
C4B63_48g118
aldehyde dehydrogenase
— Both
C4B63_13g323 ⚠
mitogen activated protein kinase
— OG6
C4B63_171g19 ⚠
mitogen activated protein kinase 4
— OG6
C4B63_4g574 ⚠
mitogen activated protein kinase 4
— OG6
C4B63_45g127
phosphoacetylglucosamine mutase
— Both
C4B63_42g180 ⚠
nitrate reductase
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.