C4B63_220g12

peroxidoxin
Trypanosoma cruzi Dm28c 2018 OG6: OG6_100111 OG7: OG7_0001516 47 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 47 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_77g29 ⚠
(H+)-ATPase G subunit
— Both
C4B63_26g257 ⚠
tryparedoxin peroxidase
— +2 more Both
C4B63_26g255 ⚠
tryparedoxin peroxidase
— +2 more Both
C4B63_149g19 ⚠
peroxidoxin
— +2 more Both
C4B63_26g253 ⚠
tryparedoxin peroxidase
— +2 more Both
C4B63_295g16 ⚠
tryparedoxin peroxidase
— +2 more Both
C4B63_295g18 ⚠
tryparedoxin peroxidase
— +2 more Both
C4B63_295g20 ⚠
tryparedoxin peroxidase
— +2 more Both
C4B63_4g331 ⚠
tubulin-specific chaperone
— Both
C4B63_26g261 ⚠
glutamate dehydrogenase
— Both
C4B63_82g96 ⚠
(H+)-ATPase G subunit
— Both
C4B63_69g74 ⚠
cytochrome c oxidase subunit V
— Both
C4B63_295g22 ⚠
tryparedoxin peroxidase
— +2 more Both
C4B63_32g225 ⚠
3-hydroxy-3-methylglutaryl-CoA synthase
— Both
C4B63_32g236 ⚠
transketolase
— Both
C4B63_123g23 ⚠
cytochrome c oxidase subunit V
— Both
C4B63_26g206 ⚠
glutaminyl-tRNA synthetase
— Both
C4B63_295g26 ⚠
glutamate dehydrogenase
— Both
C4B63_58g70 ⚠
hexokinase
— Both
C4B63_4g506 ⚠
Microtubule Associated kinase (CAP-Gly domain
— OG7
C4B63_43g161 ⚠
ATP-dependent RNA helicase SUB2
— OG7
C4B63_54g24 ⚠
ATP-dependent DEAD/H RNA helicase
— OG7
C4B63_85g83 ⚠
Eukaryotic initiation factor 4A-1
— OG7
C4B63_18g130 ⚠
glutamyl-tRNA synthetase
— OG7
C4B63_19g45 ⚠
isovaleryl-coA dehydrogenase
— Both
C4B63_143g20 ⚠
glutamine synthetase
— Both
C4B63_37g364 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— OG6
C4B63_18g233 ⚠
glyceraldehyde 3-phosphate dehydrogenase
— OG6
C4B63_8g249 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— OG6
C4B63_81g63 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— OG6
C4B63_50g7 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— OG6
C4B63_8g221 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— OG6
C4B63_26g353 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— OG6
C4B63_57g67 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— OG6
C4B63_150g38 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— OG6
C4B63_18g232 ⚠
glyceraldehyde 3-phosphate dehydrogenase
— OG6
C4B63_30g161 ⚠
glutamine synthetase
— Both
C4B63_35g189 ⚠
eukaryotic translation initiation factor 1A
— Both
C4B63_20g170 ⚠
glucosamine-6-phosphate isomerase
— Both
C4B63_12g220 ⚠
pyruvate phosphate dikinase
— Both
C4B63_12g221 ⚠
pyruvate phosphate dikinase
— Both
C4B63_101g36 ⚠
inositol-3-phosphate synthase
— Both
C4B63_355g19 ⚠
inositol-3-phosphate synthase(fragment)
— Both
C4B63_39g336 ⚠
S-adenosylhomocysteine hydrolase
— Both
C4B63_6g161 ⚠
Eukaryotic initiation factor 4A-1
— Both
C4B63_47g111 ⚠
delta-1-pyrroline-5-carboxylate dehydrogenase
— Both
C4B63_206g14 ⚠
delta-1-pyrroline-5-carboxylate dehydrogenase
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.