C4B63_69g74

cytochrome c oxidase subunit V
Trypanosoma cruzi Dm28c 2018 OG6: OG6_147143 OG7: OG7_0043911 59 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
Applies on "Apply filters".
Reset
⬇ CSV
Network view all shared interactors, plus up to 150 more
Show:
Selection: Shift+drag also box-selects. Drag any selected node to move the whole selection.
Interactions 59 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_295g22 ⚠
tryparedoxin peroxidase
— Both
C4B63_49g115 ⚠
conserved hypothetical protein
— Both
C4B63_32g225 ⚠
3-hydroxy-3-methylglutaryl-CoA synthase
— Both
C4B63_34g297 ⚠
Mitochondrial outer membrane protein porin
— Both
C4B63_34g211 ⚠
Mitochondrial outer membrane protein porin
— Both
C4B63_47g111 ⚠
delta-1-pyrroline-5-carboxylate dehydrogenase
— Both
C4B63_34g299 ⚠
Mitochondrial outer membrane protein porin
— Both
C4B63_34g298 ⚠
Mitochondrial outer membrane protein porin
— Both
C4B63_206g14 ⚠
delta-1-pyrroline-5-carboxylate dehydrogenase
— Both
C4B63_12g225 ⚠
conserved hypothetical protein
— Both
C4B63_179g1 ⚠
2-oxoglutarate dehydrogenase E1 component(fra
— Both
C4B63_220g12 ⚠
peroxidoxin
— Both
C4B63_295g16 ⚠
tryparedoxin peroxidase
— Both
C4B63_179g2 ⚠
2-oxoglutarate dehydrogenase subunit
— Both
C4B63_295g18 ⚠
tryparedoxin peroxidase
— Both
C4B63_6g256 ⚠
2-oxoglutarate dehydrogenase, E2 component, d
— Both
C4B63_19g275 ⚠
2-oxoglutarate dehydrogenase subunit
— Both
C4B63_26g257 ⚠
tryparedoxin peroxidase
— Both
C4B63_11g281 ⚠
Mucin-associated surface protein (MASP)
— OG6
C4B63_26g255 ⚠
tryparedoxin peroxidase
— Both
C4B63_149g19 ⚠
peroxidoxin
— Both
C4B63_40g18 ⚠
2-oxoglutarate dehydrogenase E1 component
— Both
C4B63_26g253 ⚠
tryparedoxin peroxidase
— Both
C4B63_295g20 ⚠
tryparedoxin peroxidase
— Both
C4B63_8g559 ⚠
Adenine phosphoribosyltransferase
— Both
C4B63_8g560 ⚠
Adenine phosphoribosyltransferase
— Both
C4B63_4g486 ⚠
glycosomal malate dehydrogenase
— OG7
C4B63_47g34 ⚠
mitochondrial malate dehydrogenase
— OG7
C4B63_54g18 ⚠
serine palmitoyltransferase
— OG7
C4B63_7g356 ⚠
serine-palmitoyl-CoA transferase
— OG7
C4B63_56g37 ⚠
ATP synthase F1, alpha subunit
— Both
C4B63_4g379 ⚠
conserved hypothetical protein
— Both
C4B63_227g5 ⚠
conserved hypothetical protein
— Both
C4B63_32g214 ⚠
2-amino-3-ketobutyrate coenzyme A ligase
— Both
C4B63_32g217 ⚠
2-amino-3-ketobutyrate coenzyme A ligase
— Both
C4B63_36g68 ⚠
mucin TcMUCII
— OG6
C4B63_47g33 ⚠
malate dehydrogenase
— Both
C4B63_12g330 ⚠
ATP synthase subunit beta, mitochondrial
— Both
C4B63_56g34 ⚠
ATP synthase F1, alpha subunit
— Both
C4B63_91g36 ⚠
ATP synthase F1, alpha subunit
— Both
C4B63_56g33 ⚠
ATP synthase F1, alpha subunit
— Both
C4B63_56g36 ⚠
ATP synthase F1, alpha subunit
— Both
C4B63_91g37 ⚠
ATP synthase F1, alpha subunit
— Both
C4B63_56g35 ⚠
ATP synthase F1, alpha subunit
— Both
C4B63_91g38 ⚠
ATP synthase F1, alpha subunit
— Both
C4B63_51g199 ⚠
SURF1-like protein
— Both
C4B63_112g17 ⚠
conserved hypothetical protein
— Both
C4B63_32g52 ⚠
Succinate dehydrogenase [ubiquinone] flavopro
— Both
C4B63_140g32 ⚠
cytochrome c oxidase VIII (COX VIII)
— Both
C4B63_44g106 ⚠
cytochrome c oxidase VIII (COX VIII)
— Both
Page 1 of 2
Next →
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.