C4B63_8g559

Adenine phosphoribosyltransferase
Trypanosoma cruzi Dm28c 2018 OG6: OG6_101012 OG7: OG7_0003957 73 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 73 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_19g43 ⚠
1,2-Dihydroxy-3-keto-5-methylthiopentene diox
— Both
C4B63_7g430 ⚠
1,2-Dihydroxy-3-keto-5-methylthiopentene diox
— Both
C4B63_1g68 ⚠
Intraflagellar transport protein 25
— Both
C4B63_286g15 ⚠
PSP1 C-terminal conserved region
— OG6
C4B63_63g4 ⚠
PSP1 C-terminal conserved region
— OG6
C4B63_111g26 ⚠
cell cycle sequence binding phosphoprotein (R
— OG6
C4B63_70g68 ⚠
cell cycle sequence binding phosphoprotein (R
— OG6
C4B63_338g16 ⚠
cell cycle sequence binding phosphoprotein (R
— OG6
C4B63_6g394 ⚠
ribose 5-phosphate isomerase type B
— Both
C4B63_282g12 ⚠
ribose 5-phosphate isomerase type B
— Both
C4B63_42g56 ⚠
Alpha N-terminal protein methyltransferase 1
— Both
C4B63_69g74 ⚠
cytochrome c oxidase subunit V
— Both
C4B63_9g382 ⚠
conserved hypothetical protein
— Both
C4B63_40g21 ⚠
Charged multivesicular body protein 3
— Both
C4B63_14g37 ⚠
conserved hypothetical protein
— Both
C4B63_18g208 ⚠
conserved hypothetical protein
— Both
C4B63_18g278 ⚠
RNA-binding protein
— OG6
C4B63_17g73 ⚠
Probable protein phosphatase methylesterase 1
— Both
C4B63_132g66 ⚠
NUDIX hydrolase 3
— Both
C4B63_14g50 ⚠
disgorgin
— Both
C4B63_83g24 ⚠
zinc-finger (CCCH type) protein
— OG7
C4B63_22g311 ⚠
3-phosphoglycerate kinase, glycosomal
— OG7
C4B63_87g24 ⚠
nonspecific lipid-transfer protein
— OG7
C4B63_15g5 ⚠
zinc-finger CCCH domain containing protein 11
— OG7
C4B63_12g2035c ⚠
zinc-finger protein 2
— OG7
C4B63_18g169 ⚠
Zinc finger CCCH domain-containing protein 47
— OG7
C4B63_397g11 ⚠
zinc-finger CCCH domain containing protein 11
— OG7
C4B63_14g48 ⚠
rab-like GTPase activating protein
— OG7
C4B63_24g178 ⚠
conserved hypothetical protein
— OG7
C4B63_8g463 ⚠
conserved hypothetical protein
— Both
C4B63_42g216 ⚠
disgorgin
— OG7
C4B63_2g524 ⚠
Charged multivesicular body protein 3
— OG7
C4B63_9g383 ⚠
conserved hypothetical protein
— OG7
C4B63_47g33 ⚠
malate dehydrogenase
— OG7
C4B63_4g486 ⚠
glycosomal malate dehydrogenase
— OG7
C4B63_28g77 ⚠
conserved hypothetical protein
— Both
C4B63_16g91 ⚠
Bis(5'-adenosyl)-triphosphatase
— Both
C4B63_123g23 ⚠
cytochrome c oxidase subunit V
— Both
C4B63_20g361 ⚠
uracil phosphoribosyltransferase
— Both
C4B63_69g60 ⚠
conserved hypothetical protein
— Both
C4B63_144g29 ⚠
conserved hypothetical protein
— Both
C4B63_85g48 ⚠
nicotinamidase
— Both
C4B63_4g69 ⚠
mitogen-activated protein kinase kinase kinas
— OG6
C4B63_41g194 ⚠
glucose-6-phosphate isomerase, glycosomal
— Both
C4B63_10g437 ⚠
U-box domain protein
— Both
C4B63_7g72 ⚠
conserved hypothetical protein
— Both
C4B63_248g14 ⚠
glucose-6-phosphate isomerase, glycosomal
— Both
C4B63_31g85 ⚠
iron superoxide dismutase A, mitochondrial
— Both
C4B63_275g16 ⚠
ras-related GTP-binding protein
— OG6
C4B63_122g3 ⚠
ras-related GTP-binding protein
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.