C4B63_9g382

conserved hypothetical protein
Trypanosoma cruzi Dm28c 2018 OG6: OG6_158163 OG7: OG7_0029290 55 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Network view all shared interactors, plus up to 150 more
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Interactions 55 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_8g481 ⚠
conserved hypothetical protein
— Both
C4B63_84g63 ⚠
conserved hypothetical protein
— Both
C4B63_391g15 ⚠
conserved hypothetical protein
— Both
C4B63_168g17 ⚠
conserved hypothetical protein
— Both
C4B63_102g62 ⚠
conserved hypothetical protein
— Both
C4B63_4g145 ⚠
nuclear segregation protein
— Both
C4B63_45g121 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— Both
C4B63_23g264 ⚠
6-phosphofructo-2-kinase 1
— Both
C4B63_8g559 ⚠
Adenine phosphoribosyltransferase
— Both
C4B63_8g560 ⚠
Adenine phosphoribosyltransferase
— Both
C4B63_26g232 ⚠
ubiquitin hydrolase(fragment)
— Both
C4B63_26g231 ⚠
ubiquitin hydrolase(fragment)
— Both
C4B63_2g368 ⚠
conserved hypothetical protein
— Both
C4B63_8g482 ⚠
conserved hypothetical protein
— Both
C4B63_14g37 ⚠
conserved hypothetical protein
— Both
C4B63_42g216 ⚠
disgorgin
— OG7
C4B63_14g48 ⚠
rab-like GTPase activating protein
— OG7
C4B63_19g43 ⚠
1,2-Dihydroxy-3-keto-5-methylthiopentene diox
— OG7
C4B63_2g4 ⚠
ubiquitin hydrolase
— OG7
C4B63_7g391 ⚠
ubiquitin hydrolase
— OG7
C4B63_7g392 ⚠
ubiquitin hydrolase
— OG7
C4B63_233g32 ⚠
ubiquitin hydrolase
— OG7
C4B63_233g31 ⚠
ubiquitin hydrolase
— OG7
C4B63_8g540 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— OG7
C4B63_13g160 ⚠
6-phosphofructo-2-kinase/fructose-2,6-bisphos
— OG7
C4B63_61g104 ⚠
conserved hypothetical protein
— OG7
C4B63_24g227 ⚠
conserved hypothetical protein
— OG7
C4B63_24g228 ⚠
conserved hypothetical protein
— OG7
C4B63_117g55 ⚠
inosine-5'-monophosphate dehydrogenase
— Both
C4B63_361g14 ⚠
nucleoside 2-deoxyribosyltransferase
— Both
C4B63_51g209 ⚠
nucleoside 2-deoxyribosyltransferase
— Both
C4B63_21g47 ⚠
Eukaryotic translation initiation factor 4 ga
— Both
C4B63_26g261 ⚠
glutamate dehydrogenase
— Both
C4B63_295g26 ⚠
glutamate dehydrogenase
— Both
C4B63_8g463 ⚠
conserved hypothetical protein
— Both
C4B63_122g3 ⚠
ras-related GTP-binding protein
— OG6
C4B63_275g16 ⚠
ras-related GTP-binding protein
— OG6
C4B63_38g299 ⚠
inosine-5'-monophosphate dehydrogenase
— Both
C4B63_157g32 ⚠
inosine-5'-monophosphate dehydrogenase
— Both
C4B63_25g113 ⚠
GMP reductase
— OG6
C4B63_260g14 ⚠
inosine-5'-monophosphate dehydrogenase
— Both
C4B63_260g15 ⚠
inosine-5'-monophosphate dehydrogenase
— Both
C4B63_95g67 ⚠
nucleoside 2-deoxyribosyltransferase
— Both
C4B63_4g72 ⚠
fibrillarin
— Both
C4B63_207g2 ⚠
fibrillarin
— Both
C4B63_57g88 ⚠
fibrillarin
— Both
C4B63_7g430 ⚠
1,2-Dihydroxy-3-keto-5-methylthiopentene diox
— Both
C4B63_18g278
RNA-binding protein
— OG6
C4B63_9g378 ⚠
conserved hypothetical protein
— Both
C4B63_153g42 ⚠
cAMP-specific phosphodiesterase
— Both
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.