C4B63_21g47

Eukaryotic translation initiation factor 4 gamma 5
Trypanosoma cruzi Dm28c 2018 OG6: OG6_139892 OG7: OG7_0037732 112 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 112 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_17g131 ⚠
G5-interacting protein
— Both
C4B63_186g10 ⚠
G5-interacting protein
— Both
C4B63_86g69 ⚠
mucin TcMUCII
— OG6
C4B63_292g17 ⚠
translation-associated element 2
— Both
C4B63_292g16 ⚠
translation-associated element 2
— Both
C4B63_138g26 ⚠
translation-associated element 2
— Both
C4B63_183g16 ⚠
conserved hypothetical protein
— Both
C4B63_38g148 ⚠
DENN (AEX-3) domain containing protein
— Both
C4B63_183g17 ⚠
conserved hypothetical protein
— Both
C4B63_153g42 ⚠
cAMP-specific phosphodiesterase
— Both
C4B63_72g80 ⚠
cAMP-specific phosphodiesterase
— Both
C4B63_49g106 ⚠
histone H2A
— Both
C4B63_242g10 ⚠
histone H2A
— Both
C4B63_6g104 ⚠
mitochondrial RNA binding protein
— Both
C4B63_8g546
Eukaryotic translation initiation factor 4E t
— Both
C4B63_34g297 ⚠
Mitochondrial outer membrane protein porin
— Both
C4B63_34g211 ⚠
Mitochondrial outer membrane protein porin
— Both
C4B63_34g299 ⚠
Mitochondrial outer membrane protein porin
— Both
C4B63_34g298 ⚠
Mitochondrial outer membrane protein porin
— Both
C4B63_13g34 ⚠
21 kDa cyclophilin
— OG6
C4B63_149g20 ⚠
cyclophilin
— OG6
C4B63_220g13 ⚠
cyclophilin
— OG6
C4B63_19g183 ⚠
cyclophilin a
— OG6
C4B63_31g178 ⚠
Zinc phosphodiesterase ELAC protein 2
— Both
C4B63_31g177 ⚠
ribonuclease Z
— Both
C4B63_85g46 ⚠
Ring finger domain/Zn-finger in ubiquitin-hyd
— Both
C4B63_63g15
ribosomal protein L1-like protein
— Both
C4B63_79g36 ⚠
CCR4-NOT transcription complex subunit 1
— Both
C4B63_439g9 ⚠
CCR4-NOT transcription complex subunit 2
— Both
C4B63_79g39 ⚠
conserved hypothetical protein
— OG7
C4B63_6g582
conserved hypothetical protein
— OG7
C4B63_1g61 ⚠
conserved hypothetical protein
— OG7
C4B63_1g62 ⚠
conserved hypothetical protein
— OG7
C4B63_1g63 ⚠
SKP1
— OG7
C4B63_7g290 ⚠
RING finger protein ETP1
— OG7
C4B63_233g31 ⚠
ubiquitin hydrolase
— OG7
C4B63_233g32 ⚠
ubiquitin hydrolase
— OG7
C4B63_7g392 ⚠
ubiquitin hydrolase
— OG7
C4B63_61g132 ⚠
WD domain, G-beta repeat
— OG7
C4B63_17g55 ⚠
cyclin 9
— OG7
C4B63_61g104
conserved hypothetical protein
— OG7
C4B63_28g87 ⚠
ubiquitin carboxyl-terminal hydrolase
— OG7
C4B63_24g227 ⚠
conserved hypothetical protein
— OG7
C4B63_413g10 ⚠
CCR4-NOT transcription complex subunit 2
— Both
C4B63_14g40
conserved hypothetical protein
— OG7
C4B63_61g127 ⚠
histone H2A variant Z
— OG7
C4B63_44g125 ⚠
conserved hypothetical protein
— OG7
C4B63_24g228 ⚠
conserved hypothetical protein
— OG7
C4B63_41g144 ⚠
CCR4-NOT transcription complex subunit 2
— Both
C4B63_48g736c ⚠
universal minicircle sequence binding protein
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.