C4B63_186g10

G5-interacting protein
Trypanosoma cruzi Dm28c 2018 OG6: OG6_147185 OG7: OG7_0043783 85 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 85 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_21g47 ⚠
Eukaryotic translation initiation factor 4 ga
— Both
C4B63_23g264 ⚠
6-phosphofructo-2-kinase 1
— Both
C4B63_80g49 ⚠
conserved hypothetical protein
— Both
C4B63_45g121 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— Both
C4B63_46g38 ⚠
conserved hypothetical protein
— Both
C4B63_46g40 ⚠
conserved hypothetical protein
— Both
C4B63_46g35 ⚠
conserved hypothetical protein
— Both
C4B63_46g42 ⚠
conserved hypothetical protein
— Both
C4B63_4g145 ⚠
nuclear segregation protein
— Both
C4B63_102g62 ⚠
conserved hypothetical protein
— Both
C4B63_168g17 ⚠
conserved hypothetical protein
— Both
C4B63_6g119 ⚠
oxidoreductase-like protein
— Both
C4B63_9g382 ⚠
conserved hypothetical protein
— Both
C4B63_9g378 ⚠
conserved hypothetical protein
— Both
C4B63_392g12 ⚠
conserved hypothetical protein
— Both
C4B63_391g15 ⚠
conserved hypothetical protein
— Both
C4B63_84g63 ⚠
conserved hypothetical protein
— Both
C4B63_80g48 ⚠
conserved hypothetical protein
— Both
C4B63_13g161 ⚠
conserved hypothetical protein
— Both
C4B63_392g13 ⚠
conserved hypothetical protein
— Both
C4B63_2g368 ⚠
conserved hypothetical protein
— Both
C4B63_6g582 ⚠
conserved hypothetical protein
— OG7
C4B63_7g392 ⚠
ubiquitin hydrolase
— OG7
C4B63_4g118 ⚠
conserved hypothetical protein
— Both
C4B63_44g125 ⚠
conserved hypothetical protein
— OG7
C4B63_61g127 ⚠
histone H2A variant Z
— OG7
C4B63_24g228 ⚠
conserved hypothetical protein
— OG7
C4B63_24g227 ⚠
conserved hypothetical protein
— OG7
C4B63_61g104 ⚠
conserved hypothetical protein
— OG7
C4B63_13g160 ⚠
6-phosphofructo-2-kinase/fructose-2,6-bisphos
— OG7
C4B63_8g540 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— OG7
C4B63_233g31 ⚠
ubiquitin hydrolase
— OG7
C4B63_233g32 ⚠
ubiquitin hydrolase
— OG7
C4B63_26g232 ⚠
ubiquitin hydrolase(fragment)
— Both
C4B63_7g391 ⚠
ubiquitin hydrolase
— OG7
C4B63_2g4 ⚠
ubiquitin hydrolase
— OG7
C4B63_28g59 ⚠
leucine-rich repeat protein (LRRP)
— OG7
C4B63_6g392 ⚠
leucine-rich repeat protein (LRRP)
— OG7
C4B63_128g51 ⚠
NLR family CARD domain-containing protein 3
— OG7
C4B63_9g383 ⚠
conserved hypothetical protein
— OG7
C4B63_13g166 ⚠
leucine carboxyl methyltransferase
— OG7
C4B63_9g251 ⚠
cdc2-related kinase 9
— OG6
C4B63_26g231 ⚠
ubiquitin hydrolase(fragment)
— Both
C4B63_18g233 ⚠
glyceraldehyde 3-phosphate dehydrogenase
— OG6
C4B63_242g10 ⚠
histone H2A
— Both
C4B63_34g298 ⚠
Mitochondrial outer membrane protein porin
— Both
C4B63_26g353 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— OG6
C4B63_19g183 ⚠
cyclophilin a
— OG6
C4B63_6g104 ⚠
mitochondrial RNA binding protein
— Both
C4B63_8g221 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.