C4B63_44g125

conserved hypothetical protein
Trypanosoma cruzi Dm28c 2018 OG6: OG6_201518 OG7: OG7_0002341 43 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 43 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_137g49 ⚠
conserved hypothetical protein
— OG7
C4B63_48g736c ⚠
universal minicircle sequence binding protein
— OG7
C4B63_28g57 ⚠
E3 ubiquitin-protein ligase listerin
— OG7
C4B63_28g171 ⚠
RNA-binding protein 38
— OG7
C4B63_17g131 ⚠
G5-interacting protein
— OG7
C4B63_186g10 ⚠
G5-interacting protein
— OG7
C4B63_13g166 ⚠
leucine carboxyl methyltransferase
— OG7
C4B63_14g93 ⚠
Cyclin 12, L-type
— OG7
C4B63_2g799 ⚠
tRNA wybutosine-synthesizing protein 4
— OG7
C4B63_2g750 ⚠
death-receptor fusion protein (DUF2428)
— OG7
C4B63_14g80 ⚠
conserved hypothetical protein
— OG7
C4B63_323g8 ⚠
conserved hypothetical protein
— OG7
C4B63_14g79 ⚠
conserved hypothetical protein
— OG7
C4B63_18g50 ⚠
microtubule associated protein xmap215
— OG7
C4B63_14g81 ⚠
conserved hypothetical protein
— OG7
C4B63_17g55 ⚠
cyclin 9
— OG7
C4B63_6g322 ⚠
conserved hypothetical protein
— OG7
C4B63_18g263 ⚠
SPA/DENN domain containing protein
— OG7
C4B63_4g477 ⚠
Probable ATP-dependent RNA helicase DHX35
— OG7
C4B63_259g15 ⚠
Paladin
— OG7
C4B63_16g140 ⚠
Paladin
— OG7
C4B63_48g132 ⚠
universal minicircle sequence binding protein
— OG7
C4B63_7g209 ⚠
Ribonuclease P protein subunit p25-like prote
— OG7
C4B63_23g33 ⚠
conserved hypothetical protein
— OG7
C4B63_23g32 ⚠
conserved hypothetical protein
— OG7
C4B63_58g121 ⚠
ubiquitin hydrolase(fragment)
— OG7
C4B63_42g96 ⚠
ubiquitin hydrolase
— OG7
C4B63_35g128 ⚠
ubiquitin hydrolase
— OG7
C4B63_134g35 ⚠
ubiquitin hydrolase
— OG7
C4B63_30g224 ⚠
conserved hypothetical protein
— OG7
C4B63_7g210 ⚠
Ribonuclease P protein subunit p25-like prote
— OG7
C4B63_21g47 ⚠
Eukaryotic translation initiation factor 4 ga
— OG7
C4B63_69g153 ⚠
poly(A) export protein
— OG7
C4B63_28g87 ⚠
ubiquitin carboxyl-terminal hydrolase
— OG7
C4B63_8g546 ⚠
Eukaryotic translation initiation factor 4E t
— OG7
C4B63_12g235 ⚠
protein transport protein Sec31
— OG7
C4B63_133g23 ⚠
conserved hypothetical protein
— OG7
C4B63_12g234 ⚠
protein transport protein Sec31
— OG7
C4B63_189g12 ⚠
Nucleoporin NUP152
— OG7
C4B63_133g25 ⚠
conserved hypothetical protein
— OG7
C4B63_23g2 ⚠
conserved hypothetical protein
— OG7
C4B63_156g8 ⚠
conserved hypothetical protein
— OG7
C4B63_23g1 ⚠
conserved hypothetical protein
— OG7
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.