C4B63_128g51

NLR family CARD domain-containing protein 3
Trypanosoma cruzi Dm28c 2018 OG6: OG6_100018 OG7: OG7_0002649 55 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 55 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_10g446 ⚠
bardet-biedl syndrome 7 protein
— OG7
C4B63_13g166 ⚠
leucine carboxyl methyltransferase
— OG7
C4B63_2g799 ⚠
tRNA wybutosine-synthesizing protein 4
— OG7
C4B63_127g27 ⚠
Cilia- and flagella-associated protein 43
— OG7
C4B63_18g301 ⚠
conserved hypothetical protein
— OG7
C4B63_191g32 ⚠
Cilia- and flagella-associated protein 43
— OG7
C4B63_17g116 ⚠
Bardet-Biedl syndrome 9 protein
— OG7
C4B63_18g303 ⚠
conserved hypothetical protein
— OG7
C4B63_20g155 ⚠
conserved hypothetical protein,leucine-rich r
— OG7
C4B63_165g33 ⚠
Cilia- and flagella-associated protein 43
— OG7
C4B63_18g22 ⚠
kinesin
— OG7
C4B63_14g51 ⚠
Adenylate kinase 9
— OG7
C4B63_42g183 ⚠
Bardet-Biedl syndrome 2 protein
— OG7
C4B63_58g111 ⚠
Vacuolar protein sorting-associated protein 5
— OG7
C4B63_22g93 ⚠
transmembrane protein, conserved
— OG7
C4B63_20g156 ⚠
conserved hypothetical protein,leucine-rich r
— OG7
C4B63_18g302 ⚠
conserved hypothetical protein
— OG7
C4B63_164g40 ⚠
Cilia- and flagella-associated protein 43
— OG7
C4B63_41g232 ⚠
conserved hypothetical protein
— OG7
C4B63_4g118 ⚠
conserved hypothetical protein
— OG7
C4B63_79g39 ⚠
conserved hypothetical protein
— OG7
C4B63_18g156 ⚠
protein mkt1
— OG7
C4B63_2g566 ⚠
phenylalanyl-tRNA synthetase
— OG7
C4B63_46g42 ⚠
conserved hypothetical protein
— OG7
C4B63_46g35 ⚠
conserved hypothetical protein
— OG7
C4B63_46g40 ⚠
conserved hypothetical protein
— OG7
C4B63_46g38 ⚠
conserved hypothetical protein
— OG7
C4B63_6g582 ⚠
conserved hypothetical protein
— OG7
C4B63_31g98 ⚠
Autophagy protein Apg6
— OG7
C4B63_186g10 ⚠
G5-interacting protein
— OG7
C4B63_19g176 ⚠
conserved hypothetical protein
— OG7
C4B63_4g534 ⚠
conserved hypothetical protein
— OG7
C4B63_392g14 ⚠
conserved hypothetical protein
— OG7
C4B63_392g11 ⚠
conserved hypothetical protein
— OG7
C4B63_80g50 ⚠
conserved hypothetical protein
— OG7
C4B63_80g49 ⚠
conserved hypothetical protein
— OG7
C4B63_392g13 ⚠
conserved hypothetical protein
— OG7
C4B63_80g48 ⚠
conserved hypothetical protein
— OG7
C4B63_392g12 ⚠
conserved hypothetical protein
— OG7
C4B63_122g17 ⚠
conserved hypothetical protein
— OG7
C4B63_6g119 ⚠
oxidoreductase-like protein
— OG7
C4B63_18g284 ⚠
conserved hypothetical protein
— OG7
C4B63_17g131 ⚠
G5-interacting protein
— OG7
C4B63_53g152 ⚠
conserved hypothetical protein
— OG7
C4B63_13g161 ⚠
conserved hypothetical protein
— OG7
C4B63_84g63 ⚠
conserved hypothetical protein
— OG7
C4B63_391g15 ⚠
conserved hypothetical protein
— OG7
C4B63_12g195 ⚠
conserved hypothetical protein
— OG7
C4B63_70g123 ⚠
3-methylcrotonoyl-CoA carboxylase beta subuni
— OG7
C4B63_45g121 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.