C4B63_14g51

Adenylate kinase 9
Trypanosoma cruzi Dm28c 2018 OG6: OG6_144302 OG7: OG7_0010447 28 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Network view all shared interactors, plus up to 150 more
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Interactions 28 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_10g446
bardet-biedl syndrome 7 protein
— Both
C4B63_41g232
conserved hypothetical protein
— OG7
C4B63_28g59 ⚠
leucine-rich repeat protein (LRRP)
— OG7
C4B63_6g392 ⚠
leucine-rich repeat protein (LRRP)
— OG7
C4B63_128g51 ⚠
NLR family CARD domain-containing protein 3
— OG7
C4B63_31g98
Autophagy protein Apg6
— OG7
C4B63_122g17
conserved hypothetical protein
— OG7
C4B63_19g176
conserved hypothetical protein
— OG7
C4B63_128g49
nucleolar RNA helicase II
— Both
C4B63_53g152
conserved hypothetical protein
— Both
C4B63_2g154 ⚠
PRP8 protein homologue
— Both
C4B63_2g155 ⚠
PRP8 protein homologue
— Both
C4B63_6g223 ⚠
DNA topoisomerase II
— Both
C4B63_26g233 ⚠
mitochondrial DNA topoisomerase II
— Both
C4B63_8g519
NLR family CARD domain-containing protein 3
— OG6
C4B63_12g195
conserved hypothetical protein
— Both
C4B63_42g183
Bardet-Biedl syndrome 2 protein
— Both
C4B63_4g534
conserved hypothetical protein
— Both
C4B63_9g259
conserved hypothetical protein
— Both
C4B63_22g93
transmembrane protein, conserved
— Both
C4B63_95g39
conserved hypothetical protein
— Both
C4B63_18g302 ⚠
conserved hypothetical protein
— Both
C4B63_18g303 ⚠
conserved hypothetical protein
— Both
C4B63_18g301 ⚠
conserved hypothetical protein
— Both
C4B63_70g123
3-methylcrotonoyl-CoA carboxylase beta subuni
— Both
C4B63_17g116
Bardet-Biedl syndrome 9 protein
— Both
C4B63_58g111
Vacuolar protein sorting-associated protein 5
— Both
C4B63_18g22
kinesin
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.