C4B63_122g17

conserved hypothetical protein
Trypanosoma cruzi Dm28c 2018 OG6: OG6_389593 OG7: OG7_0009578 64 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 64 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_11g87 ⚠
conserved hypothetical protein
— OG7
C4B63_58g111
Vacuolar protein sorting-associated protein 5
— OG7
C4B63_53g152
conserved hypothetical protein
— OG7
C4B63_31g46 ⚠
structural maintenance of chromosome 3 protei
— OG7
C4B63_14g219
Pre-mRNA-splicing factor prp5
— OG7
C4B63_11g89 ⚠
TRAPPC8
— OG7
C4B63_2g411
conserved hypothetical protein
— OG7
C4B63_22g93
transmembrane protein, conserved
— OG7
C4B63_6g392 ⚠
leucine-rich repeat protein (LRRP)
— OG7
C4B63_28g59 ⚠
leucine-rich repeat protein (LRRP)
— OG7
C4B63_20g155 ⚠
conserved hypothetical protein,leucine-rich r
— OG7
C4B63_70g123
3-methylcrotonoyl-CoA carboxylase beta subuni
— OG7
C4B63_2g729 ⚠
structural maintenance of chromosome (SMC) fa
— OG7
C4B63_63g7 ⚠
eukaryotic translation initiation factor 3 su
— OG7
C4B63_63g10 ⚠
conserved hypothetical protein
— OG7
C4B63_18g22
kinesin
— OG7
C4B63_18g303 ⚠
conserved hypothetical protein
— OG7
C4B63_175g12
conserved hypothetical protein
— OG7
C4B63_7g421
coatomer alpha subunit
— OG7
C4B63_14g51
Adenylate kinase 9
— OG7
C4B63_42g183
Bardet-Biedl syndrome 2 protein
— OG7
C4B63_10g446
bardet-biedl syndrome 7 protein
— OG7
C4B63_20g156 ⚠
conserved hypothetical protein,leucine-rich r
— OG7
C4B63_7g67 ⚠
Sec7 guanine-nucleotide exchange factor
— OG7
C4B63_19g176
conserved hypothetical protein
— OG7
C4B63_7g68 ⚠
Brefeldin A-inhibited guanine nucleotide-exch
— OG7
C4B63_286g18 ⚠
eukaryotic translation initiation factor 3 su
— OG7
C4B63_18g302 ⚠
conserved hypothetical protein
— OG7
C4B63_52g168
Cilia- and flagella-associated protein 44
— OG7
C4B63_41g232
conserved hypothetical protein
— OG7
C4B63_31g98
Autophagy protein Apg6
— OG7
C4B63_23g265
conserved hypothetical protein
— OG7
C4B63_43g187 ⚠
structural maintenance of chromosome protein
— OG7
C4B63_54g50
conserved hypothetical protein
— OG7
C4B63_11g83
Eukaryotic translation initiation factor 3 su
— OG7
C4B63_11g88 ⚠
conserved hypothetical protein
— OG7
C4B63_12g195
conserved hypothetical protein
— OG7
C4B63_24g273 ⚠
Probable E3 ubiquitin-protein ligase HERC1
— OG7
C4B63_137g10 ⚠
Coatomer subunit gamma
— OG7
C4B63_81g14 ⚠
guanine-nucleotide exchange factor, Sec7
— OG7
C4B63_76g57 ⚠
Tripartite attachment complex protein 102
— OG7
C4B63_18g301 ⚠
conserved hypothetical protein
— OG7
C4B63_7g55 ⚠
conserved hypothetical protein
— OG7
C4B63_87g21 ⚠
conserved hypothetical protein
— OG7
C4B63_7g57 ⚠
Brefeldin A-inhibited guanine nucleotide-exch
— OG7
C4B63_7g312 ⚠
conserved hypothetical protein
— OG7
C4B63_263g1 ⚠
conserved hypothetical protein
— OG7
C4B63_76g58 ⚠
Tripartite attachment complex protein 102
— OG7
C4B63_24g272 ⚠
Zn-finger in Ran binding protein and others/S
— OG7
C4B63_20g319 ⚠
25 kDa translation elongation factor 1-beta
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.