C4B63_20g319

25 kDa translation elongation factor 1-beta
Trypanosoma cruzi Dm28c 2018 OG6: OG6_101695 OG7: OG7_0003992 74 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 74 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_48g159 ⚠
25 kDa translation elongation factor 1-beta
— Both
C4B63_24g272 ⚠
Zn-finger in Ran binding protein and others/S
— Both
C4B63_34g374 ⚠
ribosomal RNA processing protein 41B
— OG7
C4B63_42g202 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_8g521 ⚠
GPN-loop GTPase 2
— OG7
C4B63_279g6 ⚠
DNA-directed RNA polymerase II subunit 2
— OG7
C4B63_44g250 ⚠
DNA-directed RNA polymerase II subunit 2
— OG7
C4B63_102g61 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_11g83 ⚠
Eukaryotic translation initiation factor 3 su
— Both
C4B63_24g273 ⚠
Probable E3 ubiquitin-protein ligase HERC1
— Both
C4B63_173g5 ⚠
ribosomal RNA processing protein 41B
— OG7
C4B63_19g82 ⚠
RNA polymerase I second largest subunit
— Both
C4B63_20g197 ⚠
exosome-associated protein 2
— Both
C4B63_57g92 ⚠
Ribosomal RNA processing protein 41A
— Both
C4B63_49g170 ⚠
ribosomal RNA processing protein 45
— Both
C4B63_12g298 ⚠
GPN-loop GTPase 3
— Both
C4B63_12g318 ⚠
conserved hypothetical protein
— Both
C4B63_20g211 ⚠
Telomerase Cajal body protein 1
— Both
C4B63_267g18 ⚠
conserved hypothetical protein
— Both
C4B63_72g94 ⚠
ribosomal RNA processing protein 40
— Both
C4B63_7g55 ⚠
conserved hypothetical protein
— OG7
C4B63_95g43 ⚠
conserved hypothetical protein
— OG7
C4B63_26g206 ⚠
glutaminyl-tRNA synthetase
— OG7
C4B63_54g50 ⚠
conserved hypothetical protein
— OG7
C4B63_11g90 ⚠
conserved hypothetical protein
— OG7
C4B63_122g17 ⚠
conserved hypothetical protein
— OG7
C4B63_87g20 ⚠
Brefeldin A-inhibited guanine nucleotide-exch
— OG7
C4B63_7g57 ⚠
Brefeldin A-inhibited guanine nucleotide-exch
— OG7
C4B63_87g21 ⚠
conserved hypothetical protein
— OG7
C4B63_16g154 ⚠
exosome component CSL4
— Both
C4B63_81g14 ⚠
guanine-nucleotide exchange factor, Sec7
— OG7
C4B63_7g56 ⚠
Protein transport protein sec71
— OG7
C4B63_81g15 ⚠
guanine-nucleotide exchange factor, Sec7
— OG7
C4B63_279g5 ⚠
DNA-directed RNA polymerase II subunit 2
— OG7
C4B63_194g21 ⚠
DNA-directed RNA polymerase III
— OG7
C4B63_168g16 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_42g203 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_40g162 ⚠
exosome-associated protein 4
— OG7
C4B63_18g223 ⚠
eukaryotic translation initiation factor 3 su
— Both
C4B63_263g3 ⚠
conserved hypothetical protein
— Both
C4B63_286g21 ⚠
conserved hypothetical protein
— Both
C4B63_63g45 ⚠
methyltransferase
— Both
C4B63_22g93 ⚠
transmembrane protein, conserved
— Both
C4B63_2g411 ⚠
conserved hypothetical protein
— Both
C4B63_7g68 ⚠
Brefeldin A-inhibited guanine nucleotide-exch
— Both
C4B63_7g67 ⚠
Sec7 guanine-nucleotide exchange factor
— Both
C4B63_22g174 ⚠
exosome-associated protein 1
— Both
C4B63_7g312 ⚠
conserved hypothetical protein
— Both
C4B63_11g87 ⚠
conserved hypothetical protein
— Both
C4B63_11g89 ⚠
TRAPPC8
— Both
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.