C4B63_22g174

exosome-associated protein 1
Trypanosoma cruzi Dm28c 2018 OG6: OG6_146086 OG7: OG7_0043575 42 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 42 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_72g94
ribosomal RNA processing protein 40
— Both
C4B63_304g10 ⚠
DNA-directed RNA polymerase III subunit C11
— OG7
C4B63_19g82 ⚠
RNA polymerase I second largest subunit
— Both
C4B63_45g218 ⚠
conserved hypothetical protein
— Both
C4B63_45g216 ⚠
conserved hypothetical protein
— Both
C4B63_45g217 ⚠
WD40 repeat protein
— Both
C4B63_45g105 ⚠
DNA polymerase sigma
— Both
C4B63_323g12 ⚠
protein kinase
— OG6
C4B63_23g3 ⚠
protein kinase
— OG6
C4B63_156g10 ⚠
protein kinase
— OG6
C4B63_4g2794c ⚠
DNA-directed RNA polymerase III subunit C11
— OG7
C4B63_20g197 ⚠
exosome-associated protein 2
— Both
C4B63_18g156 ⚠
protein mkt1
— OG7
C4B63_44g250 ⚠
DNA-directed RNA polymerase II subunit 2
— OG7
C4B63_279g6 ⚠
DNA-directed RNA polymerase II subunit 2
— OG7
C4B63_8g521 ⚠
GPN-loop GTPase 2
— OG7
C4B63_34g374 ⚠
ribosomal RNA processing protein 41B
— OG7
C4B63_173g5 ⚠
ribosomal RNA processing protein 41B
— OG7
C4B63_194g21 ⚠
DNA-directed RNA polymerase III
— OG7
C4B63_279g5 ⚠
DNA-directed RNA polymerase II subunit 2
— OG7
C4B63_8g520 ⚠
DNA polymerase sigma-like protein
— OG7
C4B63_38g158 ⚠
Poly(A) RNA polymerase cid14
— OG7
C4B63_49g173 ⚠
conserved hypothetical protein
— Both
C4B63_53g162
conserved hypothetical protein
— Both
C4B63_40g114
glycosyl hydrolase
— Both
C4B63_49g174 ⚠
conserved hypothetical protein
— Both
C4B63_40g80 ⚠
DNA-directed RNA polymerase I subunit
— Both
C4B63_8g513
conserved hypothetical protein
— Both
C4B63_54g15
Fatty acid oxidation complex subunit alpha
— Both
C4B63_79g39 ⚠
conserved hypothetical protein
— Both
C4B63_44g149
conserved hypothetical protein
— Both
C4B63_42g82
RNA-binding protein
— OG6
C4B63_57g92 ⚠
Ribosomal RNA processing protein 41A
— Both
C4B63_232g18
exosome complex exonuclease
— Both
C4B63_16g154
exosome component CSL4
— Both
C4B63_48g159 ⚠
25 kDa translation elongation factor 1-beta
— Both
C4B63_40g162 ⚠
exosome-associated protein 4
— Both
C4B63_267g18 ⚠
conserved hypothetical protein
— Both
C4B63_20g319 ⚠
25 kDa translation elongation factor 1-beta
— Both
C4B63_12g318 ⚠
conserved hypothetical protein
— Both
C4B63_12g298 ⚠
GPN-loop GTPase 3
— Both
C4B63_49g170 ⚠
ribosomal RNA processing protein 45
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.