C4B63_4g2794c

DNA-directed RNA polymerase III subunit C11
Trypanosoma cruzi Dm28c 2018 OG6: OG6_101491 OG7: OG7_0002891 49 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
Applies on "Apply filters".
Reset
⬇ CSV
Network view all shared interactors, plus up to 150 more
Show:

Selection: Shift+drag also box-selects. Drag any selected node to move the whole selection.
Interactions 49 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_45g105 ⚠
DNA polymerase sigma
— OG7
C4B63_267g91c ⚠
DNA-directed RNA polymerase I subunit RPB10
— OG7
C4B63_279g5 ⚠
DNA-directed RNA polymerase II subunit 2
— OG7
C4B63_19g82 ⚠
RNA polymerase I second largest subunit
— OG7
C4B63_45g216 ⚠
conserved hypothetical protein
— OG7
C4B63_45g217 ⚠
WD40 repeat protein
— OG7
C4B63_45g218 ⚠
conserved hypothetical protein
— OG7
C4B63_26g318 ⚠
conserved hypothetical protein
— OG7
C4B63_136g39 ⚠
conserved hypothetical protein
— OG7
C4B63_49g174 ⚠
conserved hypothetical protein
— OG7
C4B63_49g173 ⚠
conserved hypothetical protein
— OG7
C4B63_4g197 ⚠
DNA-directed RNA polymerase I subunit RPB5z
— OG7
C4B63_8g520 ⚠
DNA polymerase sigma-like protein
— OG7
C4B63_6g1831c ⚠
DNA-dependent RNA polymerases
— OG7
C4B63_38g158 ⚠
Poly(A) RNA polymerase cid14
— OG7
C4B63_5g418 ⚠
DNA-directed RNA polymerase III subunit
— OG7
C4B63_17g120 ⚠
RNA polymerase-like protein
— OG7
C4B63_1g75 ⚠
DNA-directed RNA polymerase III subunit
— OG7
C4B63_40g114 ⚠
glycosyl hydrolase
— OG7
C4B63_72g94 ⚠
ribosomal RNA processing protein 40
— OG7
C4B63_22g262c ⚠
DNA-directed RNA polymerase 2, RPB12 subunit
— OG7
C4B63_54g15 ⚠
Fatty acid oxidation complex subunit alpha
— OG7
C4B63_79g39 ⚠
conserved hypothetical protein
— OG7
C4B63_18g156 ⚠
protein mkt1
— OG7
C4B63_8g513 ⚠
conserved hypothetical protein
— OG7
C4B63_104g76 ⚠
RNA polymerase IIA largest subunit
— OG7
C4B63_44g149 ⚠
conserved hypothetical protein
— OG7
C4B63_53g162 ⚠
conserved hypothetical protein
— OG7
C4B63_55g67 ⚠
DNA-directed rna polymerase I largest subunit
— OG7
C4B63_44g250 ⚠
DNA-directed RNA polymerase II subunit 2
— OG7
C4B63_279g6 ⚠
DNA-directed RNA polymerase II subunit 2
— OG7
C4B63_12g1641c ⚠
DNA-directed RNA polymerase I subunit RPB10
— OG7
C4B63_6g101 ⚠
RNA polymerase B subunit RPB8
— OG7
C4B63_230g118c ⚠
DNA-dependent RNA polymerases
— OG7
C4B63_61g127 ⚠
histone H2A variant Z
— OG7
C4B63_46g417c ⚠
DNA-directed RNA polymerase I subunit
— OG7
C4B63_10g482 ⚠
conserved hypothetical protein
— OG7
C4B63_22g174 ⚠
exosome-associated protein 1
— OG7
C4B63_104g75 ⚠
RNA polymerase IIA largest subunit
— OG7
C4B63_49g106 ⚠
histone H2A
— OG7
C4B63_358g16 ⚠
RNA polymerase IIA largest subunit
— OG7
C4B63_4g478 ⚠
DNA-directed RNA polymerases I and III subuni
— OG7
C4B63_2g2395c ⚠
DNA-directed RNA polymerase II
— OG7
C4B63_255g16 ⚠
RNA polymerase IIA largest subunit
— OG7
C4B63_321g29 ⚠
RNA polymerase IIA largest subunit
— OG7
C4B63_10g507 ⚠
DNA-directed RNA polymerases I and III subuni
— OG7
C4B63_47g56 ⚠
RNA polymerase IIA largest subunit
— OG7
C4B63_242g10 ⚠
histone H2A
— OG7
C4B63_194g21 ⚠
DNA-directed RNA polymerase III
— OG7
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.