C4B63_13g161

conserved hypothetical protein
Trypanosoma cruzi Dm28c 2018 OG6: OG6_138753 OG7: OG7_0034063 171 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 171 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_348g23 ⚠
cytochrome b5
— OG7
C4B63_109g39 ⚠
kinetoplast polyadenylation/uridylation facto
— Both
C4B63_49g81 ⚠
translation initiation factor IF-2
— Both
C4B63_2g799 ⚠
tRNA wybutosine-synthesizing protein 4
— Both
C4B63_11g9
eukaryotic translation initiation factor 3 su
— Both
C4B63_227g2 ⚠
glucan 1,3-alpha-glucosidase
— Both
C4B63_4g375 ⚠
glucan 1,3-alpha-glucosidase
— Both
C4B63_23g207 ⚠
tRNA (cytosine(34)-C(5))-methyltransferase
— Both
C4B63_81g44 ⚠
tRNA (cytosine(34)-C(5))-methyltransferase
— Both
C4B63_54g28
conserved hypothetical protein
— Both
C4B63_184g38 ⚠
TPR-repeat protein
— OG6
C4B63_13g167 ⚠
stress-inducible protein STI1-like
— OG6
C4B63_175g8 ⚠
TPR-repeat protein
— OG6
C4B63_23g110 ⚠
UDP-glucose:glycoprotein glucosyltransferase
— Both
C4B63_23g109 ⚠
UDP-glucose:glycoprotein glucosyltransferase
— Both
C4B63_93g69
tRNA (Uracil-5-)-methyltransferase
— Both
C4B63_19g137 ⚠
cleavage and polyadenylation specificity fact
— Both
C4B63_49g164 ⚠
alanyl-tRNA synthetase
— Both
C4B63_49g165 ⚠
alanyl-tRNA synthetase
— Both
C4B63_49g166 ⚠
alanyl-tRNA synthetase
— Both
C4B63_9g251
cdc2-related kinase 9
— OG6
C4B63_6g521 ⚠
DIS3-like exonuclease
— Both
C4B63_109g37 ⚠
Gar1/Naf1 RNA binding region containing prote
— Both
C4B63_34g118 ⚠
conserved hypothetical protein
— Both
C4B63_56g84 ⚠
conserved hypothetical protein
— Both
C4B63_56g85 ⚠
conserved hypothetical protein
— Both
C4B63_14g97 ⚠
isoleucyl-tRNA synthetase
— Both
C4B63_14g96 ⚠
isoleucil-tRNA synthetase
— Both
C4B63_23g248 ⚠
inorganic pyrophosphatase
— Both
C4B63_70g77 ⚠
acidocalcisomal pyrophosphatase
— Both
C4B63_149g26
GDP-mannose pyrophosphorylase
— Both
C4B63_61g23 ⚠
tRNA-dihydrouridine synthase 3
— Both
C4B63_339g3 ⚠
tRNA-dihydrouridine synthase 3
— Both
C4B63_30g129 ⚠
rrp44p homologue
— OG7
C4B63_276g11 ⚠
DIS3-like exonuclease(fragment)
— OG7
C4B63_72g106 ⚠
DIS3-like exonuclease(fragment)
— OG7
C4B63_34g372 ⚠
cytochrome b-domain protein
— OG7
C4B63_7g306 ⚠
cleavage and polyadenylation specificity fact
— OG7
C4B63_70g572c ⚠
cytochrome b5
— OG7
C4B63_1g121c ⚠
cytochrome b5-like protein
— OG7
C4B63_8g211 ⚠
cytochrome b
— OG7
C4B63_10g403 ⚠
cytochrome b5
— OG7
C4B63_25g1526c ⚠
Acyl-lipid (8-3)-desaturase
— OG7
C4B63_313g3 ⚠
dihydrouridine synthase (Dus)(fragment)
— OG7
C4B63_425g4 ⚠
tyrosyl or methionyl-tRNA synthetase
— OG7
C4B63_294g18 ⚠
dihydrouridine synthase (Dus)
— OG7
C4B63_13g118 ⚠
tRNA-dihydrouridine synthase 2
— OG7
C4B63_20g51 ⚠
tRNA-dihydrouridine synthase 4
— OG7
C4B63_336g10 ⚠
dihydrouridine synthase (Dus)
— OG7
C4B63_294g17 ⚠
dihydrouridine synthase (Dus)
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.