C4B63_81g44

tRNA (cytosine(34)-C(5))-methyltransferase
Trypanosoma cruzi Dm28c 2018 OG6: OG6_101428 OG7: OG7_0004943 183 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 183 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_93g69 ⚠
tRNA (Uracil-5-)-methyltransferase
— Both
C4B63_21g255 ⚠
Nucleolar protein 56
— OG7
C4B63_40g52 ⚠
conserved hypothetical protein
— Both
C4B63_10g517 ⚠
tryptophanyl-tRNA synthetase
— OG6
C4B63_4g214 ⚠
cyclophilin type peptidyl-prolyl cis-trans is
— OG6
C4B63_4g213 ⚠
cyclophilin type peptidyl-prolyl cis-trans is
— OG6
C4B63_54g22 ⚠
conserved hypothetical protein
— Both
C4B63_184g38 ⚠
TPR-repeat protein
— OG6
C4B63_13g167 ⚠
stress-inducible protein STI1-like
— OG6
C4B63_175g8 ⚠
TPR-repeat protein
— OG6
C4B63_23g110 ⚠
UDP-glucose:glycoprotein glucosyltransferase
— Both
C4B63_23g109 ⚠
UDP-glucose:glycoprotein glucosyltransferase
— Both
C4B63_49g164 ⚠
alanyl-tRNA synthetase
— Both
C4B63_49g165 ⚠
alanyl-tRNA synthetase
— Both
C4B63_49g166 ⚠
alanyl-tRNA synthetase
— Both
C4B63_6g521 ⚠
DIS3-like exonuclease
— Both
C4B63_19g26 ⚠
guide RNA-binding protein of 21 kDa
— Both
C4B63_109g37 ⚠
Gar1/Naf1 RNA binding region containing prote
— Both
C4B63_34g118 ⚠
conserved hypothetical protein
— Both
C4B63_56g84 ⚠
conserved hypothetical protein
— Both
C4B63_56g85 ⚠
conserved hypothetical protein
— Both
C4B63_14g97 ⚠
isoleucyl-tRNA synthetase
— Both
C4B63_14g96 ⚠
isoleucil-tRNA synthetase
— Both
C4B63_102g61 ⚠
aspartyl-tRNA synthetase
— Both
C4B63_42g202 ⚠
aspartyl-tRNA synthetase
— Both
C4B63_42g203 ⚠
aspartyl-tRNA synthetase
— Both
C4B63_168g16 ⚠
aspartyl-tRNA synthetase
— Both
C4B63_23g248 ⚠
inorganic pyrophosphatase
— Both
C4B63_70g77 ⚠
acidocalcisomal pyrophosphatase
— Both
C4B63_42g42 ⚠
co-chaperone GrpE
— Both
C4B63_30g129 ⚠
rrp44p homologue
— OG7
C4B63_276g11 ⚠
DIS3-like exonuclease(fragment)
— OG7
C4B63_72g106 ⚠
DIS3-like exonuclease(fragment)
— OG7
C4B63_4g72 ⚠
fibrillarin
— OG7
C4B63_207g2 ⚠
fibrillarin
— OG7
C4B63_30g232 ⚠
protein arginine n-methyltransferase 7
— OG7
C4B63_6g440 ⚠
tRNA pseudouridine synthase
— OG7
C4B63_57g88 ⚠
fibrillarin
— OG7
C4B63_73g1 ⚠
arginine N-methyltransferase
— OG7
C4B63_23g39 ⚠
arginine N-methyltransferase
— OG7
C4B63_45g133 ⚠
splicing factor TSR1
— OG7
C4B63_58g56 ⚠
conserved hypothetical protein
— OG7
C4B63_26g214 ⚠
nucleolar RNA binding protein
— OG7
C4B63_60g173 ⚠
arginine N-methyltransferase, type I
— OG7
C4B63_20g184 ⚠
Pseudouridylate synthase 7 homolog-like prote
— OG7
C4B63_6g439 ⚠
tRNA pseudouridine synthase
— OG7
C4B63_41g251 ⚠
arginine N-methyltransferase
— OG7
C4B63_13g118 ⚠
tRNA-dihydrouridine synthase 2
— OG7
C4B63_336g10 ⚠
dihydrouridine synthase (Dus)
— OG7
C4B63_20g51 ⚠
tRNA-dihydrouridine synthase 4
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.