C4B63_11g9

eukaryotic translation initiation factor 3 subunit j

Trypanosoma cruzi Dm28c 2018 OG6: OG6_146907 OG7: OG7_0043230 158 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 158 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
C4B63_72g106 ⚠ DIS3-like exonuclease(fragment)	—	OG7 TCSYLVIO_002525 ↔ TCSYLVIO_006404 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_006404	OG7
C4B63_61g23 ⚠ tRNA-dihydrouridine synthase 3	—	OG6 TCSYLVIO_006404 ↔ TCSYLVIO_009102 OG7 TCSYLVIO_006404 ↔ TCSYLVIO_009102	Both
C4B63_13g161 conserved hypothetical protein	—	OG6 TCSYLVIO_006404 ↔ TCSYLVIO_009932 OG7 TCSYLVIO_006404 ↔ TCSYLVIO_009932	Both
C4B63_19g195 Nuclear pore complex protein 158	—	OG6 TCSYLVIO_006404 ↔ TCSYLVIO_007387 OG7 TCSYLVIO_006404 ↔ TCSYLVIO_007387	Both
C4B63_93g64 ⚠ amidohydrolase	—	OG6 TCSYLVIO_006404 ↔ TCSYLVIO_008414 OG7 TCSYLVIO_006404 ↔ TCSYLVIO_008414	Both
C4B63_101g15 serine peptidase, Clan SC, Family S9B	—	OG6 TCSYLVIO_006404 ↔ TCSYLVIO_007536 OG7 TCSYLVIO_006404 ↔ TCSYLVIO_007536	Both
C4B63_82g71 ⚠ tryptophanyl-tRNA synthetase	—	OG6 TCSYLVIO_006404 ↔ TCSYLVIO_010724	OG6
C4B63_244g4 ⚠ Nuclear migration protein nudC	—	OG6 TCSYLVIO_006404 ↔ TCSYLVIO_010327 OG7 TCSYLVIO_006404 ↔ TCSYLVIO_010327	Both
C4B63_40g52 conserved hypothetical protein	—	OG6 TCSYLVIO_006404 ↔ TCSYLVIO_008197 OG7 TCSYLVIO_006404 ↔ TCSYLVIO_008197	Both
C4B63_10g517 ⚠ tryptophanyl-tRNA synthetase	—	OG6 TCSYLVIO_006404 ↔ TCSYLVIO_010724	OG6
C4B63_4g375 ⚠ glucan 1,3-alpha-glucosidase	—	OG6 TCSYLVIO_006140 ↔ TCSYLVIO_006404 OG6 TCSYLVIO_006141 ↔ TCSYLVIO_006404 OG7 TCSYLVIO_006140 ↔ TCSYLVIO_006404 OG7 TCSYLVIO_006141 ↔ TCSYLVIO_006404	Both
C4B63_23g207 ⚠ tRNA (cytosine(34)-C(5))-methyltransferase	—	OG6 TCSYLVIO_004998 ↔ TCSYLVIO_006404 OG7 TCSYLVIO_004998 ↔ TCSYLVIO_006404	Both
C4B63_81g44 ⚠ tRNA (cytosine(34)-C(5))-methyltransferase	—	OG6 TCSYLVIO_004998 ↔ TCSYLVIO_006404 OG7 TCSYLVIO_004998 ↔ TCSYLVIO_006404	Both
C4B63_54g28 conserved hypothetical protein	—	OG6 TCSYLVIO_005084 ↔ TCSYLVIO_006404 OG7 TCSYLVIO_005084 ↔ TCSYLVIO_006404	Both
C4B63_184g38 ⚠ TPR-repeat protein	—	OG6 TCSYLVIO_003496 ↔ TCSYLVIO_006404	OG6
C4B63_13g167 ⚠ stress-inducible protein STI1-like	—	OG6 TCSYLVIO_003496 ↔ TCSYLVIO_006404	OG6
C4B63_175g8 ⚠ TPR-repeat protein	—	OG6 TCSYLVIO_003496 ↔ TCSYLVIO_006404	OG6
C4B63_23g110 ⚠ UDP-glucose:glycoprotein glucosyltransferase	—	OG6 TCSYLVIO_004363 ↔ TCSYLVIO_006404 OG7 TCSYLVIO_004363 ↔ TCSYLVIO_006404	Both
C4B63_23g109 ⚠ UDP-glucose:glycoprotein glucosyltransferase	—	OG6 TCSYLVIO_004363 ↔ TCSYLVIO_006404 OG7 TCSYLVIO_004363 ↔ TCSYLVIO_006404	Both
C4B63_49g164 ⚠ alanyl-tRNA synthetase	—	OG6 TCSYLVIO_001889 ↔ TCSYLVIO_006404 OG7 TCSYLVIO_001889 ↔ TCSYLVIO_006404	Both
C4B63_19g137 ⚠ cleavage and polyadenylation specificity fact	—	OG6 TCSYLVIO_005414 ↔ TCSYLVIO_006404 OG7 TCSYLVIO_005414 ↔ TCSYLVIO_006404	Both
C4B63_49g165 ⚠ alanyl-tRNA synthetase	—	OG6 TCSYLVIO_001889 ↔ TCSYLVIO_006404 OG7 TCSYLVIO_001889 ↔ TCSYLVIO_006404	Both
C4B63_49g166 ⚠ alanyl-tRNA synthetase	—	OG6 TCSYLVIO_001889 ↔ TCSYLVIO_006404 OG7 TCSYLVIO_001889 ↔ TCSYLVIO_006404	Both
C4B63_6g521 ⚠ DIS3-like exonuclease	—	OG6 TCSYLVIO_002525 ↔ TCSYLVIO_006404 OG6 TCSYLVIO_002526 ↔ TCSYLVIO_006404 OG7 TCSYLVIO_002525 ↔ TCSYLVIO_006404 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_006404	Both
C4B63_109g37 ⚠ Gar1/Naf1 RNA binding region containing prote	—	OG6 TCSYLVIO_000836 ↔ TCSYLVIO_006404 OG7 TCSYLVIO_000836 ↔ TCSYLVIO_006404	Both
C4B63_34g118 ⚠ conserved hypothetical protein	—	OG6 TCSYLVIO_000836 ↔ TCSYLVIO_006404 OG7 TCSYLVIO_000836 ↔ TCSYLVIO_006404	Both
C4B63_56g84 ⚠ conserved hypothetical protein	—	OG6 TCSYLVIO_001973 ↔ TCSYLVIO_006404 OG7 TCSYLVIO_001973 ↔ TCSYLVIO_006404	Both
C4B63_56g85 ⚠ conserved hypothetical protein	—	OG6 TCSYLVIO_001973 ↔ TCSYLVIO_006404 OG7 TCSYLVIO_001973 ↔ TCSYLVIO_006404	Both
C4B63_14g97 ⚠ isoleucyl-tRNA synthetase	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_006404 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_006404	Both
C4B63_14g96 ⚠ isoleucil-tRNA synthetase	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_006404 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_006404	Both
C4B63_102g61 ⚠ aspartyl-tRNA synthetase	—	OG6 TCSYLVIO_003107 ↔ TCSYLVIO_006404 OG7 TCSYLVIO_003107 ↔ TCSYLVIO_006404 OG7 TCSYLVIO_003867 ↔ TCSYLVIO_006404	Both
C4B63_42g202 ⚠ aspartyl-tRNA synthetase	—	OG6 TCSYLVIO_003107 ↔ TCSYLVIO_006404 OG7 TCSYLVIO_003107 ↔ TCSYLVIO_006404 OG7 TCSYLVIO_003867 ↔ TCSYLVIO_006404	Both
C4B63_42g203 ⚠ aspartyl-tRNA synthetase	—	OG6 TCSYLVIO_003107 ↔ TCSYLVIO_006404 OG7 TCSYLVIO_003107 ↔ TCSYLVIO_006404 OG7 TCSYLVIO_003867 ↔ TCSYLVIO_006404	Both
C4B63_168g16 ⚠ aspartyl-tRNA synthetase	—	OG6 TCSYLVIO_003107 ↔ TCSYLVIO_006404 OG7 TCSYLVIO_003107 ↔ TCSYLVIO_006404 OG7 TCSYLVIO_003867 ↔ TCSYLVIO_006404	Both
C4B63_23g248 ⚠ inorganic pyrophosphatase	—	OG6 TCSYLVIO_001709 ↔ TCSYLVIO_006404 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_006404	Both
C4B63_70g77 ⚠ acidocalcisomal pyrophosphatase	—	OG6 TCSYLVIO_001709 ↔ TCSYLVIO_006404 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_006404	Both
C4B63_42g42 co-chaperone GrpE	—	OG6 TCSYLVIO_003139 ↔ TCSYLVIO_006404 OG7 TCSYLVIO_003139 ↔ TCSYLVIO_006404	Both
C4B63_30g129 ⚠ rrp44p homologue	—	OG7 TCSYLVIO_002525 ↔ TCSYLVIO_006404 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_006404	OG7
C4B63_193g9 ⚠ metallo-peptidase, Clan MF, Family M17	—	OG7 TCSYLVIO_005560 ↔ TCSYLVIO_006404	OG7
C4B63_276g11 ⚠ DIS3-like exonuclease(fragment)	—	OG7 TCSYLVIO_002525 ↔ TCSYLVIO_006404 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_006404	OG7
C4B63_3g864 ⚠ Mucin-associated surface protein (MASP)	—	OG7 TCSYLVIO_002771 ↔ TCSYLVIO_006404	OG7
C4B63_2g798 ⚠ Putative pentatricopeptide repeat-containing	—	OG7 TCSYLVIO_000834 ↔ TCSYLVIO_006404	OG7
C4B63_14g48 ⚠ rab-like GTPase activating protein	—	OG7 TCSYLVIO_004663 ↔ TCSYLVIO_006404	OG7
C4B63_42g216 ⚠ disgorgin	—	OG7 TCSYLVIO_004663 ↔ TCSYLVIO_006404	OG7
C4B63_40g73 ⚠ glycosyl hydrolase-like protein	—	OG7 TCSYLVIO_006140 ↔ TCSYLVIO_006404 OG7 TCSYLVIO_006141 ↔ TCSYLVIO_006404	OG7
C4B63_206g11 ⚠ ABC transporter	—	OG7 TCSYLVIO_006012 ↔ TCSYLVIO_006404	OG7
C4B63_294g18 ⚠ dihydrouridine synthase (Dus)	—	OG7 TCSYLVIO_006404 ↔ TCSYLVIO_009102	OG7
C4B63_47g107 ⚠ ABC transporter	—	OG7 TCSYLVIO_006012 ↔ TCSYLVIO_006404	OG7
C4B63_25g214 ⚠ conserved hypothetical protein	—	OG7 TCSYLVIO_004998 ↔ TCSYLVIO_006404	OG7
C4B63_113g34 ⚠ ABC transporter	—	OG7 TCSYLVIO_006012 ↔ TCSYLVIO_006404	OG7

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