C4B63_41g194

glucose-6-phosphate isomerase, glycosomal
Trypanosoma cruzi Dm28c 2018 OG6: OG6_100716 OG7: OG7_0004783 50 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 50 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_2g752 ⚠
6-phosphogluconate dehydrogenase, decarboxyla
— Both
C4B63_81g63 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— OG6
C4B63_50g7 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— OG6
C4B63_85g54 ⚠
fatty acyl CoA synthetase 2
— Both
C4B63_8g221 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— OG6
C4B63_25g288 ⚠
inosine-guanine nucleoside hydrolase
— Both
C4B63_32g236 ⚠
transketolase
— Both
C4B63_7g302 ⚠
aldose 1-epimerase-like protein
— Both
C4B63_18g164 ⚠
S-adenosylmethionine synthetase
— Both
C4B63_26g206 ⚠
glutaminyl-tRNA synthetase
— Both
C4B63_206g21 ⚠
fatty acyl CoA synthetase
— Both
C4B63_10g404 ⚠
guanine deaminase
— Both
C4B63_26g353 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— OG6
C4B63_2g292 ⚠
glyceraldehyde-3-phosphate dehydrogenase
— OG6
C4B63_57g67 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— OG6
C4B63_150g38 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— OG6
C4B63_85g55 ⚠
fatty acyl CoA syntetase 1
— Both
C4B63_85g51 ⚠
fatty acyl CoA syntetase 1
— Both
C4B63_18g232 ⚠
glyceraldehyde 3-phosphate dehydrogenase
— OG6
C4B63_87g24 ⚠
nonspecific lipid-transfer protein
— OG7
C4B63_18g130 ⚠
glutamyl-tRNA synthetase
— OG7
C4B63_17g115 ⚠
ADP-ribosylation factor GTPase activating pro
— OG7
C4B63_17g265 ⚠
Probable ADP-ribosylation factor GTPase-activ
— OG7
C4B63_6g417 ⚠
ADP-ribosylation factor GTPase activating pro
— OG7
C4B63_10g489 ⚠
ADP-ribosylation factor GTPase activating pro
— OG7
C4B63_348g24 ⚠
guanine deaminase
— Both
C4B63_75g70 ⚠
ADP-ribosylation factor GTPase activating pro
— Both
C4B63_8g559 ⚠
Adenine phosphoribosyltransferase
— Both
C4B63_8g560 ⚠
Adenine phosphoribosyltransferase
— Both
C4B63_7g72 ⚠
conserved hypothetical protein
— Both
C4B63_4g69 ⚠
mitogen-activated protein kinase kinase kinas
— OG6
C4B63_16g302 ⚠
3-ketoacyl-CoA thiolase
— Both
C4B63_54g69 ⚠
aspartate aminotransferase
— Both
C4B63_28g64 ⚠
aspartate aminotransferase
— Both
C4B63_30g144 ⚠
Cilia- and flagella-associated protein 52
— Both
C4B63_4g324 ⚠
aconitase
— Both
C4B63_170g28 ⚠
adenylosuccinate synthetase
— Both
C4B63_85g53 ⚠
fatty acyl CoA synthetase 2
— Both
C4B63_10g437 ⚠
U-box domain protein
— Both
C4B63_47g115 ⚠
fatty acyl CoA synthetase
— Both
C4B63_20g170 ⚠
glucosamine-6-phosphate isomerase
— Both
C4B63_19g45 ⚠
isovaleryl-coA dehydrogenase
— Both
C4B63_37g364 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— OG6
C4B63_18g233 ⚠
glyceraldehyde 3-phosphate dehydrogenase
— OG6
C4B63_4g146 ⚠
pyruvate kinase 2
— Both
C4B63_227g20 ⚠
pyruvate kinase 2
— Both
C4B63_46g82 ⚠
adenylosuccinate synthetase
— Both
C4B63_4g184 ⚠
citrate synthase
— Both
C4B63_8g249 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— OG6
C4B63_86g56 ⚠
glyceraldehyde-3-phosphate dehydrogenase
— OG6
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.