C4B63_17g115

ADP-ribosylation factor GTPase activating protein 1
Trypanosoma cruzi Dm28c 2018 OG6: OG6_102808 OG7: OG7_0001719 50 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Network view all shared interactors, plus up to 150 more
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Interactions 50 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_230g12 ⚠
Mitochondrial import receptor subunit ATOM69
— Both
C4B63_160g33 ⚠
ubiquitin-activating enzyme E1
— Both
C4B63_18g260
small glutamine-rich tetratricopeptide repeat
— OG6
C4B63_56g67 ⚠
Sperm-tail PG-rich repeat-containing protein
— Both
C4B63_243g7 ⚠
conserved hypothetical protein
— Both
C4B63_28g28 ⚠
copper homeostasis protein
— Both
C4B63_12g179 ⚠
anion-transporting ATPase-like
— Both
C4B63_212g12 ⚠
anion-transporting ATPase-like
— Both
C4B63_7g391 ⚠
ubiquitin hydrolase
— Both
C4B63_7g392 ⚠
ubiquitin hydrolase
— Both
C4B63_20g357 ⚠
Carnosine N-methyltransferase
— Both
C4B63_29g174 ⚠
protein phosphatase 1, regulatory subunit
— Both
C4B63_33g137 ⚠
protein phosphatase 1, regulatory subunit
— Both
C4B63_2g786 ⚠
ubiquitin-activating enzyme E1
— Both
C4B63_6g205 ⚠
Mitochondrial import receptor subunit ATOM69
— Both
C4B63_42g42 ⚠
co-chaperone GrpE
— Both
C4B63_26g232 ⚠
ubiquitin hydrolase(fragment)
— OG7
C4B63_2g4 ⚠
ubiquitin hydrolase
— OG7
C4B63_26g231 ⚠
ubiquitin hydrolase(fragment)
— OG7
C4B63_233g32 ⚠
ubiquitin hydrolase
— OG7
C4B63_233g31 ⚠
ubiquitin hydrolase
— OG7
C4B63_30g144 ⚠
Cilia- and flagella-associated protein 52
— OG7
C4B63_41g194 ⚠
glucose-6-phosphate isomerase, glycosomal
— OG7
C4B63_248g14 ⚠
glucose-6-phosphate isomerase, glycosomal
— OG7
C4B63_24g203 ⚠
conserved hypothetical protein
— OG7
C4B63_2g416 ⚠
conserved hypothetical protein
— Both
C4B63_153g42 ⚠
cAMP-specific phosphodiesterase
— Both
C4B63_13g208 ⚠
conserved hypothetical protein,zinc finger pr
— Both
C4B63_23g131 ⚠
protein farnesyltransferase alpha subunit
— Both
C4B63_26g304 ⚠
conserved hypothetical protein
— Both
C4B63_2g211 ⚠
Flagellum attachment zone protein 4
— Both
C4B63_2g362 ⚠
conserved hypothetical protein
— Both
C4B63_83g72 ⚠
replication Factor A 28 kDa subunit
— Both
C4B63_72g80 ⚠
cAMP-specific phosphodiesterase
— Both
C4B63_2g415 ⚠
conserved hypothetical protein
— Both
C4B63_26g306 ⚠
conserved hypothetical protein
— Both
C4B63_23g76 ⚠
ubiquitin carboxyl-terminal hydrolase
— Both
C4B63_80g27 ⚠
SNAP protein
— Both
C4B63_6g113 ⚠
ribonucleoside-diphosphate reductase large ch
— Both
C4B63_26g305 ⚠
conserved hypothetical protein
— Both
C4B63_93g71 ⚠
soluble N-ethylmaleimide sensitive factor (NS
— Both
C4B63_25g232 ⚠
Tetratricopeptide repeat protein 27 homolog
— Both
C4B63_267g8 ⚠
Structure-specific endonuclease subunit SLX1
— Both
C4B63_267g7 ⚠
GIY-YIG catalytic domain containing protein
— Both
C4B63_2g417 ⚠
conserved hypothetical protein
— Both
C4B63_12g310 ⚠
Structure-specific endonuclease subunit SLX1
— Both
C4B63_77g29 ⚠
(H+)-ATPase G subunit
— Both
C4B63_82g96 ⚠
(H+)-ATPase G subunit
— Both
C4B63_18g153 ⚠
T-complex protein 11
— Both
C4B63_16g331 ⚠
ubiquitin-activating enzyme E1
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.