C4B63_30g161

glutamine synthetase
Trypanosoma cruzi Dm28c 2018 OG6: OG6_100668 OG7: OG7_0003785 93 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 93 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_149g26 ⚠
GDP-mannose pyrophosphorylase
— Both
C4B63_42g66 ⚠
conserved hypothetical protein
— Both
C4B63_3g553 ⚠
NADH-dependent fumarate reductase
— Both
C4B63_58g52 ⚠
conserved hypothetical protein
— Both
C4B63_58g53 ⚠
conserved hypothetical protein
— Both
C4B63_184g8 ⚠
GTP-binding protein
— Both
C4B63_9g201 ⚠
GTP-binding protein
— Both
C4B63_40g52 ⚠
conserved hypothetical protein
— Both
C4B63_268g24 ⚠
HSPBP1
— Both
C4B63_20g355 ⚠
HSPBP1
— Both
C4B63_31g181 ⚠
mitochondrial DNA polymerase beta
— Both
C4B63_4g513 ⚠
Target of rapamycin complex subunit LST8
— Both
C4B63_7g79 ⚠
aspartyl-tRNA synthetase
— Both
C4B63_3g552 ⚠
NADH-dependent fumarate reductase
— Both
C4B63_39g336 ⚠
S-adenosylhomocysteine hydrolase
— Both
C4B63_306g12 ⚠
glucose-6-phosphate 1-dehydrogenase
— Both
C4B63_98g4 ⚠
glucose-6-phosphate 1-dehydrogenase
— Both
C4B63_135g22 ⚠
Glucose-6-phosphate dehydrogenase
— Both
C4B63_47g24 ⚠
Glucose-6-phosphate dehydrogenase
— Both
C4B63_355g19 ⚠
inositol-3-phosphate synthase(fragment)
— Both
C4B63_101g36 ⚠
inositol-3-phosphate synthase
— Both
C4B63_12g221 ⚠
pyruvate phosphate dikinase
— Both
C4B63_12g220 ⚠
pyruvate phosphate dikinase
— Both
C4B63_22g114 ⚠
DnaJ chaperone protein
— Both
C4B63_20g152 ⚠
Uncharacterized GTP-binding protein C428.15
— OG7
C4B63_102g61 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_168g16 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_42g203 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_42g202 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_28g59 ⚠
leucine-rich repeat protein (LRRP)
— OG7
C4B63_6g392 ⚠
leucine-rich repeat protein (LRRP)
— OG7
C4B63_128g51 ⚠
NLR family CARD domain-containing protein 3
— OG7
C4B63_13g166 ⚠
leucine carboxyl methyltransferase
— OG7
C4B63_31g180 ⚠
mitochondrial DNA polymerase beta-PAK
— OG7
C4B63_31g179 ⚠
mitochondrial DNA polymerase beta-PAK
— OG7
C4B63_9g270 ⚠
GTP-binding protein
— OG7
C4B63_15g18 ⚠
NADH-dependent fumarate reductase
— Both
C4B63_18g130 ⚠
glutamyl-tRNA synthetase
— OG7
C4B63_76g51 ⚠
Protein IWS1 homolog
— Both
C4B63_2g425 ⚠
succinyl-coA:3-ketoacid-coenzyme A transferas
— Both
C4B63_3g551 ⚠
NADH-dependent fumarate reductase
— Both
C4B63_3g554 ⚠
NADH-dependent fumarate reductase
— Both
C4B63_54g70 ⚠
NADH-dependent fumarate reductase
— Both
C4B63_15g19 ⚠
NADH-dependent fumarate reductase
— Both
C4B63_54g71 ⚠
NADH-dependent fumarate reductase
— Both
C4B63_3g550 ⚠
NADH-dependent fumarate reductase
— Both
C4B63_2g448 ⚠
Unc104-like kinesin
— OG6
C4B63_26g206 ⚠
glutaminyl-tRNA synthetase
— Both
C4B63_57g67 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— OG6
C4B63_26g353 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.