C4B63_28g122

conserved hypothetical protein
Trypanosoma cruzi Dm28c 2018 OG6: OG6_158151 OG7: OG7_0052371 75 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 75 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_41g200 ⚠
Anaphase-promoting complex subunit 8
— +2 more Both
C4B63_18g71 ⚠
cyclosome subunit
— Both
C4B63_14g250 ⚠
Anaphase-promoting complex subunit 3
— +2 more Both
C4B63_18g72 ⚠
cyclosome subunit
— Both
C4B63_278g6 ⚠
endosomal trafficking protein RME-8
— Both
C4B63_1g57 ⚠
AAA ATPase
— Both
C4B63_186g7 ⚠
cleavage and polyadenylation specificity fact
— Both
C4B63_18g325 ⚠
endosomal trafficking protein RME-8
— Both
C4B63_127g30 ⚠
Flagellum attachment zone protein 14
— Both
C4B63_48g155 ⚠
conserved hypothetical protein
— OG6
C4B63_48g156 ⚠
conserved hypothetical protein
— OG6
C4B63_10g105 ⚠
kinesin protein
— OG6
C4B63_58g35 ⚠
E3 ubiquitin-protein ligase RBX1
— OG7
C4B63_6g418 ⚠
protein kinase
— Both
C4B63_4g103 ⚠
intraflagellar transport protein 140
— Both
C4B63_9g223 ⚠
Cilia- and flagella-associated protein 57
— Both
C4B63_9g224 ⚠
Cilia- and flagella-associated protein 57
— Both
C4B63_80g9 ⚠
conserved hypothetical protein
— Both
C4B63_19g137 ⚠
cleavage and polyadenylation specificity fact
— Both
C4B63_80g10 ⚠
E3 ubiquitin-protein ligase HECTD3
— Both
C4B63_48g153 ⚠
N-terminal region of Chorein, a TM vesicle-me
— OG6
C4B63_127g31 ⚠
Flagellum attachment zone protein 14
— OG7
C4B63_7g236 ⚠
regulatory subunit of protein kinase a-like p
— OG7
C4B63_80g15 ⚠
cAMP response protein 1
— OG7
C4B63_51g192 ⚠
protein kinase A regulatory subunit
— OG7
C4B63_22g288 ⚠
Midasin
— OG7
C4B63_7g306 ⚠
cleavage and polyadenylation specificity fact
— OG7
C4B63_351g1 ⚠
conserved hypothetical protein
— OG7
C4B63_55g168 ⚠
Cilia- and flagella-associated protein 57
— OG7
C4B63_22g166 ⚠
Regulatory-associated protein of mTOR
— OG7
C4B63_32g248 ⚠
conserved hypothetical protein
— OG7
C4B63_31g221 ⚠
RING-box protein 1A
— OG7
C4B63_42g198 ⚠
conserved hypothetical protein
— OG7
C4B63_42g199 ⚠
conserved hypothetical protein
— OG7
C4B63_10g125 ⚠
ankyrin
— OG7
C4B63_56g58 ⚠
ankyrin,
— OG7
C4B63_2g828 ⚠
ankyrin repeat protein
— OG7
C4B63_31g98 ⚠
Autophagy protein Apg6
— OG7
C4B63_31g1443c ⚠
RING-box protein 1
— OG7
C4B63_17g128 ⚠
cleavage and polyadenylation specificity fact
— Both
C4B63_35g117 ⚠
conserved hypothetical protein
— OG6
C4B63_4g525 ⚠
anaphase promoting complex, subunit 10-like p
— Both
C4B63_38g152 ⚠
tetratricopeptide repeat protein (TPR)
— Both
C4B63_38g151 ⚠
tetratricopeptide repeat protein (TPR)
— Both
C4B63_85g63 ⚠
Rab-GTPase-TBC domain containing protein
— Both
C4B63_30g176 ⚠
inorganic polyphosphate/ATP-NAD kinase
— Both
C4B63_143g33 ⚠
inorganic polyphosphate/ATP-NAD kinase
— Both
C4B63_35g116 ⚠
VPS13A C
— OG6
C4B63_35g118 ⚠
conserved hypothetical protein
— OG6
C4B63_128g60 ⚠
zinc-finger protein family member
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.